Treat Non-Severe PreE with BP Meds?
From Dr. Chapa's OBGYN No Spin Podcast by Hector Chapa
May 31, 2026 · 15 min
About this episode
The episode discusses the debate over treating non-severe preeclampsia with antihypertensive medications during expectant management.
Welcome back, everyone. Today we're diving into one of the most hotly debated topics in obstetrics- should we be treating preeclampsia without severe features with antihypertensive medications during expectant management? Now, if you've been following the literature- and our show, you know that the landmark CHAP trial changed the game for chronic hypertension in pregnancy. It showed us that targeting a blood pressure below 140 over 90 reduces serious maternal complications, without harming the baby. That was a big deal. But here's the thing, CHAP studied chronic hypertension. Then there was the CHIP trial- that also found that tight control of gestational hypertension and nonproteinuric chronic hypertension was also beneficial. These did not address preeclampsia without severe features, and yet, the ripple effects of that trial have sparked a global conversation about whether we should be extending those same treatment principles to women with preeclampsia who don't yet have severe features. And this is where it gets really interesting, because the guidelines don't agree. In the United States, ACOG and the Society for Maternal-Fetal Medicine still say: hold off on…
People in this episode
Host: Hector Chapa
Topics covered
- preeclampsia
- antihypertensive medications
- obstetrics
- maternal health
- guidelines
- blood pressure management
Keywords
- preeclampsia
- hypertension
- pregnancy
- maternal complications
- blood pressure
- guidelines
- CHAP trial
- CHIP trial
Mentioned in this episode
Organizations: ACOG, Society for Maternal-Fetal Medicine, World Health Organization, International Society for the Study of Hypertension in Pregnancy, FIGO, NICE, Hypertension Canada
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