The Science of Hangovers: Why Most “Cures” Fail

The Science of Hangovers: Why Most “Cures” Fail

From Fork U with Dr. Terry Simpson by Terry Simpson

May 21, 2026 · 15 min · Episode 128

About this episode

This episode explores the science behind hangovers and why common cures often fail.

The Science of Hangovers: Why Your “Cure” Probably Doesn’t Work You wake up thirsty. Then, almost immediately, you realize your head hurts. Your stomach feels unstable. The room is too bright. Your mouth tastes like regret and old wine corks. Furthermore, your intestines suddenly decided today is the day they become extremely efficient. In other words, you have a hangover. Now, hopefully, this is not a regular occurrence. Nevertheless, most adults eventually experience one. The evening starts innocently enough: good friends, great conversation, maybe a cocktail before dinner. Then, however, another bottle arrives. Someone orders dessert drinks. Suddenly, what seemed like sophisticated socializing turns into next-morning negotiations with your nervous system. And that raises the obvious question: What actually causes a hangover ? More importantly, why do so many supposed “cures” fail so spectacularly? First, Alcohol Is Not Just “Dehydration” Many people think a hangover is simply dehydration. Certainly, dehydration matters. Alcohol suppresses vasopressin, the hormone that helps your kidneys conserve water. As a result, you urinate more frequently. Consequently, you lose fluid and…

People in this episode

Host: Terry Simpson

Topics covered

  • hangovers
  • alcohol
  • dehydration
  • health
  • nutrition
  • science

Keywords

  • hangover
  • cure
  • alcohol
  • dehydration
  • stomach lining
  • blood sugar
  • inflammatory pathways

More episodes of Fork U with Dr. Terry Simpson

Explore listener stats, chart rankings, contacts and more on the Fork U with Dr. Terry Simpson podcast page.