Headshake

THE BRAIN IS HUNGRY FOR PEOPLE. Keeping in mind new experiences of isolation during the pandemic, recent research shows parallels between a socially-deprived brain craving people and a fasted brain craving food. Full notes at headshake.show/episodes/34

The letter A is always red to some people. To others, the sound of a car horn might always smell like pie. Libby and Ruka sensually explore the rare but real condition of synesthesia. Full notes at headshake.show/episodes/32

Returning to the land of electrophysiology, Lord Nathan and Lady Kristen focus this time on action potentials, which neurons use to send electrical signals long distances in the body. God save the Baked Bean! Full notes at headshake.show/episodes/30

It's Headshake's anniversary, and the finale of the Gap Junction Almanac. We hope you've had the "Time of Your Life," and we'll still be "Friends Forever." Let's cheer ourselves up with a discussion of seasonal affective disorder (SAD). Key Words bipolar ii, circadian rhythm, cognitive behavioral therapy (CBT), depression, heritable, light box, light therapy, lux, major depression, melatonin, norepinephrine-dopamine reuptake inhibitor (NDRI), psychotherapy, seasonal affective disorder (SAD), selective serotonin reuptake inhibitor (SSRI), serotonin, summer pattern, vitamin D, winter pattern Old West Word of the Day (Gap Junction Almanac) Anglomaniacs Lots of old west insults - Listen to the episode for a season finale's worth of insults References and Resources NIMH » Seasonal Affective Disorder (nih.gov), National Institute of Mental Health Seasonal affective disorder (SAD) - Symptoms and causes, Mayo Clinic Are You Affected By Seasonal Affective Disorder (SAD)?, Psychology Today ClimaTemps http://www.madison.climatemps.com/sunlight.php https://www.oahu.climatemps.com/sunlight.php Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Season 1 Spotify Playlist! HEADSHAKE: The Playlist Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Early Bird Science - Ruka's other science podcast earlybirdscience.com Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

There are two kilograms (4.4 pounds) of microbes in your gut. Are these little residents controlling your brain? If so, how? Poop Detectives Libby and Ruka are on the case. Key Words autism, bacteria, depression, enteroendocrine, fecal transplant, gamma aminobutyric acid (GABA), gastrointestinal (GI) system, gut flora, gut microbiome, immune cells, inflammation, irritable bowel syndrome (IBS), kynurenine, neuropod cells, Parkinson's disease, psychobiome, psychobiotics, schizophrenia, serotonin, tryptophan, Valsalva maneuver Old West Words of the Day (Gap Junction Almanac) Yack Yam References and Resources Meet the 'psychobiome': the gut bacteria that may alter how you think, feel, and act, Science Magazine, May 7, 2020 Season 1 Spotify Playlist! HEADSHAKE: The Playlist Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

This is part one of two episodes about the auditory system. You could say it's a "preliminary hearing." Key Words amplitude, audition, auditory system, aurical, cochlea, cochlear duct, deaf, decibel, eardrum, endolymph, eustachian tube, external auditory canal, frequency, hearing impaired, hearing, helicotrema, incus, inner ear, malleus, middle ear, organ of Corti, outer ear, oval window, perilymph, pinna, pitch, round window, scala tympani, scala vestibuli, stapes, tympanic membrane, volume, zone of compression, zone of rarefaction Old West Words of the Day (Gap Junction Almanac) Wearing the bustle wrong Wipe your chin BRAND NEW Season 1 Spotify Playlist! HEADSHAKE: The Playlist Reference Textbook: Vander's Human Physiology, 13th Edition Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

Who are you?! Oh, right. Hi, Jeff! Sorry about that. Our forgetting neurons were working particularly hard last night. Yes, you have neurons that make you forget. Turns out they're important in memory. This Episode's Spotify Playlist Neuralized Key Words action potential, amygdala, anxiety, appetite, CA1, calcium transients, chemogenetics, consolidation, contextual fear conditioning (CFC), cued fear, dreams, electroencephalogram (EEG), electromyography (EMG), electrophysiology, fiber photometry, forget, GABA, GABA-ergic, glutamate, hippocampus, hypothalamus, immunohistochemistry, inhibitory post-synaptic current (IPSC), limbic, melanin-concentrating hormone (MCH) neurons, memory, microendoscopy, novel object recognition (NOR), optogenetics, retention, retrobeads Old West Word of the Day (Gap Junction Almanac) Unsalted References and Resources Primary research paper: REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories, Science, 20 Sept 2019 "Kid's Menu:" Scientists Find The Neurons That Make Your Brain Forget Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

Headshake's personal chef (a.k.a. Ruka's spouse) is also an electrical and electronic engineer. Steven A. Gago helps Libby and Ruka tackle the mysteries of newly-developed microcircuit chips that could one day become implants to replace diseased neurons. Key Words Alzheimer's, analog, assimilate, bioimplant, Bötzinger region, brain stem, bursts, CA1, chip, circuit, current, digital, hardware, hippocampus, Hodgkin-Huxley model, medulla, model, pyramidal cells, respiratory neuron, solid state neuron, soma, transistor, very-large-scale integration (VLSI) Old West Words of the Day (Gap Junction Almanac) There you ain't Teapot Tin Toad strangler References and Resources Artificial neurons developed to fight disease, BBC, December 2019 Optimal solid state neurons, Abu-Hassan et al, Nature Communications, December 2019 Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

Does listening to Headshake activate your fight or flight response? Or maybe it leaves you comfortably in your rest and digest state. Ruka and Libby talk about the differences between these systems while planning Libby's self-eulogized Viking funeral. Key Words acetylcholine, adrenal medulla, adrenaline, afferent, autonomic motor, autonomic nervous system, blood pressure, central nervous system (CNS), cervical, collateral ganglia, efferent, enteric, epinephrine, fight or flight response, ganglion, gastrointestinal (GI) tract, glucose, heart rate, heart, homeostasis, innervate, liver, lumbar, norepinephrine, parasympathetic, peripheral nervous system (PNS), postganglionic, preganglionic, pupils, rest and digest state, sacral, somatic motor, somatic nervous system, somatic sensory, special sensory, spinal cord, stress, sympathetic trunk, sympathetic, thoracic, visceral sensory Old West Words of the Day (Gap Junction Almanac) Rumbumptious Rum hole References and Resources Textbook: Vander's Human Physiology, 13th Edition Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

Libby and Ruka learn about the strange but harmless experience of being awake and not being able to move. This episode is brought to you by the letter P and delicious chocolate frosted Kooky Monkey Brains: "They're mentally delicious." Key Words atonia, brain stem, general anxiety disorder, glycine, hallucinate, interneurons, jet lag, medulla, midbrain, narcolepsy, non-rem, panic disorder, pons, post traumatic stress disorder (PTSD), rapid eye movement (REM), REM-off, REM-on, shift work, sleep offset paralysis, sleep onset paralysis, sleep paralysis, sleep phase, spinal cord Old West Word of the Day (Gap Junction Almanac) Piece of pudding Pecker pole References and Resources Sleep Paralysis and the Monsters Inside Your Mind, Scientific American Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Sleep Paralysis, NHS Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

A discussion of the hypothalamus and posterior pituitary gets derailed when Libby uncovers Ruka's painfully comprehensive reserve of 2000's boy band knowledge. Key Words anterior pituitary, antidiuretic hormone (ADH), autonomic, Bader-Meinhof phenomenon, diencephalon, endocrine, epithalamus, frequency illusion, hypophysis, hypothalamo-hypophysial portal vessels, hypothalamus, infundibulum, lactation, magnocellular neuron, mammillary bodies, median eminence, nuclei, optic chiasm, osmolality, oxytocin, paraventricular nucleus, pituitary, portal vasculature, portal veins, posterior pituitary, recency illusion, sella turcica, somatic, sphenoid, supraoptic nucleus, thalamus, third ventricle, uterine contraction, vasopressin, viscerosensory transduction Old West Words of the Day (Gap Junction Almanac) Nanny Neck oil Nose paint Necessary References and Resources Textbooks Vander's Human Physiology, 13th Edition Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Fundamental Neuroscience for Basic and Clinical Applications, Haines, 3rd Edition Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

It's Headshake's first guest ever! Theanne Griffith, Ph.D. joins as a third host to discuss her neuroscience research on specialized ion channels in cold sensation, as well as her brand new STEM-themed children's book series The Magnificent Makers! Dr. Griffith's research starts at 00:23:47 The Magnificent Makers starts at 01:02:56 Key Words action potential, blocker, caliper, chemotherapy-induced peripheral neuropathy, cold-sensitive neurons, diversity, dorsal root ganglia (DRG) neurons, F & P text level Q, firing, ganglia, genetic approaches, implicit bias, ion channel, labeled line theory, model, peripheral nervous system, pharmacological approaches, representation, sensory neurons, somatic sensation, splanchnic, TRPM8, two-point discrimination Old West Word of the Day (Gap Junction Almanac) Like bricks Dr. Theanne Griffith's Research Dr. Griffith's latest publication in The Journal of Neuroscience: Tetrodotoxin-Sensitive Sodium Channels Mediate Action Potential Firing and Excitability in Menthol-Sensitive Vglut3-Lineage Sensory Neurons Publication that references Dr. Griffith's above paper: The Sensory Coding of Warm Perception The Magnificent Makers "BOOM! SNAP! WHIZ! ZAP! A modern-day Magic School Bus for chapter book readers!" Check out Dr. Griffith's brand new STEM-themed children's book series, a great gift for your favorite curious 7-10 year-old! https://www.theannegriffith.com/books Please consider purchasing from your local independent and/or Black-owned bookseller: https://www.indiebound.org/ List of Black-owned booksellers (also includes stores that may not be Black-owned but specialize in Black literature) If you cannot currently purchase The Magnificent Makers, be sure to request the series at your local library! Connect with Dr. Griffith! Facebook, Twitter, and Instagram: @doctheagrif Site theannegriffith.com Connect with The Magnificent Makers illustrator Reggie Brown! Facebook Instagram: @reggiebrownart Site: https://trendingcreativedesign.com/ Connect with Headshake! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. The hosts are not medical doctors, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

Your body isn't strung with copper wire. So how does the nervous system send electrical signals? Libby and Ruka discuss this question and attempt to do math. When you're done listening, remember to write that letter to your Nana Amps. She misses you. Key Words action potential, axon terminal, axon, cell membrane, current, electrical potential, excitatory, extracellular, gap junction, graded potential, inhibitory, intracellular, ions, leak channels, megaohms (mΩ), membrane potential, millivolts (mV), myelin, Na+/K+-ATPase, nanoamps (nA), negative charge, Ohm's law, pacemaker potential, permeability, positive charge, potential difference, potential, propagation, receptor potential, resistance, resting membrane potential, signal transduction, synaptic potential, threshold, transmembrane potential, V=IR, volts Old West Words of the Day John B. John Barleycorn Brother Jonathan Connect with us! FB @HeadshakeShow T @HeadshakeShow 'Sta @HeadshakeNinja Site headshake.show OR headshake.ninja References Textbooks Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Vander's Human Physiology, 13th Edition Music Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002 Artist: http://incompetech.com/ Modified from original with volume fading and cuts Disclaimer This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.