Season 1 Episode 8: Lipoprotein (a)

Season 1 Episode 8: Lipoprotein (a)

From LipidCurious by Vishnu Priya Pulipati, MD, FACE, DipABCL

October 31, 2025 · 14 min · Season 1 · Episode 8

About this episode

This episode discusses Lipoprotein(a) and its role as a significant genetic driver of cardiovascular disease.

LDL may get all the blame — but there’s a darker twin hiding in the shadows. Same cholesterol core. Same ApoB backbone. But with one sinister twist: a sticky tail called apolipoprotein(a). That extra piece transforms an ordinary LDL particle into something far more dangerous. Meet Lipoprotein(a) — or Lp(a) — one of the strongest, most under-recognized genetic drivers of premature cardiovascular disease. It’s pro-atherogenic, pro-thrombotic, and pro-inflammatory — a triple threat that ca...

People in this episode

Host: Vishnu Priya Pulipati, MD, FACE, DipABCL

Topics covered

  • Lipoprotein(a)
  • cardiovascular disease
  • cholesterol
  • genetic factors
  • atherosclerosis
  • inflammation

Keywords

  • Lipoprotein(a)
  • LDL
  • cardiovascular disease
  • cholesterol
  • apolipoprotein
  • atherogenic
  • thrombotic
  • inflammatory

Mentioned in this episode

Products: Lipoprotein(a), LDL, Apolipoprotein(a)

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