
Season 1 Episode 8: Lipoprotein (a)
From LipidCurious by Vishnu Priya Pulipati, MD, FACE, DipABCL
October 31, 2025 · 14 min · Season 1 · Episode 8
About this episode
This episode discusses Lipoprotein(a) and its role as a significant genetic driver of cardiovascular disease.
LDL may get all the blame — but there’s a darker twin hiding in the shadows. Same cholesterol core. Same ApoB backbone. But with one sinister twist: a sticky tail called apolipoprotein(a). That extra piece transforms an ordinary LDL particle into something far more dangerous. Meet Lipoprotein(a) — or Lp(a) — one of the strongest, most under-recognized genetic drivers of premature cardiovascular disease. It’s pro-atherogenic, pro-thrombotic, and pro-inflammatory — a triple threat that ca...
People in this episode
Host: Vishnu Priya Pulipati, MD, FACE, DipABCL
Topics covered
- Lipoprotein(a)
- cardiovascular disease
- cholesterol
- genetic factors
- atherosclerosis
- inflammation
Keywords
- Lipoprotein(a)
- LDL
- cardiovascular disease
- cholesterol
- apolipoprotein
- atherogenic
- thrombotic
- inflammatory
Mentioned in this episode
Products: Lipoprotein(a), LDL, Apolipoprotein(a)
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