The Real World vs The Trial Patient: Bridging the Gap

The Real World vs The Trial Patient: Bridging the Gap

From Oncology Data Advisor by i3 Health

May 11, 2026 · 20 min

About this episode

This episode discusses the gap between clinical trial populations and real-world oncology patients.

Check out the full article at: https://oncdata.com/oncology-unfiltered-the-real-world-vs-the-trial-patient Every oncologist knows the moment well: you're reviewing treatment options with a patient, guidelines in hand, when you realize the person sitting across from you wouldn't have qualified for the pivotal trial that established your recommended therapy. In this episode of Oncology Unfiltered, Melissa Cutrona, Co-Founder and General Manager of i3 Health and Oncology Data Advisor, speaks with Dr. Matthew Hadfield, Oncology Data Advisor Editor in Chief, about one of oncology's most persistent challenges—the widening gap between carefully curated trial populations and the complex, real-world patients who enter clinics daily.

People in this episode

Host: Melissa Cutrona

Guest: Dr. Matthew Hadfield

Topics covered

  • oncology
  • clinical trials
  • real-world evidence
  • patient care
  • treatment options

Keywords

  • oncology
  • clinical trials
  • real-world patients
  • treatment guidelines
  • patient care

Mentioned in this episode

Organizations: i3 Health, Oncology Data Advisor

More episodes of Oncology Data Advisor

Explore listener stats, chart rankings, contacts and more on the Oncology Data Advisor podcast page.