Open Source Startup Podcast

This Open Source Startup Podcast episode has our co-hosts Robby and Tim in conversation with Dr. Felipe Huici, CEO of Unikraft - the compute layer for sandboxes, AI agents, or any workload with VM-grade isolation. Their open source, also called unikraft, has 4K stars on GitHub and provides a next-generation cloud native kernel. This episode explores how Unikraft is building infrastructure for the next generation of AI agents, arguing that agents should run in virtual machines rather than containers. The conversation focuses on the unique requirements of agentic workloads: fast startup times, the ability to pause and resume state, strong isolation, and efficient resource utilization at massive scale. Unikraft’s technology enables lightweight virtual machines that can start in under 10 milliseconds, helping companies reduce latency, lower infrastructure costs, and run large numbers of ephemeral agents on minimal hardware. The discussion also covers emerging AI infrastructure needs such as checkpointing, branching, headless browser automation, and GPU access.The podcast also traces Unikraft’s origins from an academic research project to an open-source Linux Foundation initiative and, eventually, a startup founded in 2022. The conversation examines customer adoption, the role of Unikraft as foundational infrastructure for AI platforms, competition and collaboration within the agent ecosystem, the future of GPUs and virtualization, and lessons learned from building a company in the rapidly evolving cloud and AI infrastructure market.

In the episode, we sat down with ClickHouse Co-Founder Yury Izrailevsky to unpack how one of the fastest open-source databases in the world became the analytics engine of choice for 2,000 customers including Harvey, Canva, HP, and Supabase. From its Yandex origins to powering AI observability, Yury shares how ClickHouse balances open-source roots, cloud innovation, and a remote-first culture moving at breakneck speed.ClickHouse's Series C valued the company at $6.35B earlier this year, and just yesterday they announced an extension to that round, just months after it was raised. In this episode, we dig into:Origins & Founding StoryClickHouse began as an internal project at Yandex to power a Google Analytics–style platform, focused on performance and scale.Open-sourced in 2016 - rapid global adoption laid the foundation for ClickHouse the company. Yury first discovered ClickHouse while at Google; impressed by its speed, he later co-founded the company in 2021 alongside Aaron Katz (ex-Elastic) and the original creator Alexey Milovidov.Why ClickHouse Stands OutColumn-oriented, open source OLAP database designed for massive-scale analytical processing.Excels in performance, efficiency, and cost - ideal for large data volumes and real-time analytics (and now AI workloads). Architectural choices:Columnar storage = better compression and faster execution.Separation of compute and storage enables elasticity, scalability, and resilience in the cloud.Open Source vs. CloudOpen-source version offers freedom and flexibility.Cloud product delivers much lower total cost of ownership and fully managed experience.Architectural parity between the two ensuring no vendor lock-in for customers. Customers can run the same queries on both; most stay with cloud due to simplicity and cost efficiency.Use Cases & Ecosystem4 main use cases:Real-time analyticsData WarehousingObservability AI / ML WorkloadsCompany Building & CultureFully remote from day one.Prioritized experienced, self-sufficient engineers over early-career hires.Built and launched GA version in less than a year - insane pace of innovation.Innovation & CommunityMonthly release cadence.Hundreds of integrations and connectors.Strong open-source and commercial communityAdvice for FoundersFocus on what matters most Hire mature, independent thinkers.Move fast but maintain quality; ClickHouse Cloud achieved production-grade quality in record time.

Ryan Djurovich is the Founder & CEO of Nadrama, the open source infrastructure automation platform that deploys containers instantly. In this episode, we dig into:Kubernetes challenges that still exist today – setup and operations are notoriously hard and complex.What great developer experience means to him – focused on making deployments super simple by streamlining infrastructure and common tasks.Core value of Nadrama – developers just want to deploy apps; Nadrama abstracts away infrastructure pain.His view on what being truly open source means (including using the Apache 2.0 license) Ryan's user discovery process - talking directly with as many users as possible, mining his network / folks he's worked with in the past, community events & meetups.Navigating the earliest days of Nadrama Security philosophy – believes in baseline security for all accounts (not just enterprise), informed by a Cloudflare background.

Emma Burrows is Co-Founder & CTO of Portia AI, the platform to build AI agents in regulated environments. Their open source Python SDK provides a developer framework for predictable and stateful agentic workflows. Portia AI has raised around $5M from investors including General Catalyst and First Minute Capital.In this episode, we dig into:Why they built an end-to-end platform from agent planning to deployment The focus on accuracy as their true north star metric Their paid contribution program How their found their initial ICP in regulated industries Why 2026 will be the year of agents Her best fundraising advice (hint: never really stop fundraising)

Vasek Mlejnsky is Co-Founder & CEO of E2B, the open-source runtime for executing AI-generated code in secure cloud sandboxes. Essentially, they give AI agents cloud computers. Their open source repos, particularly e2b which has 9K GitHub stars, have been widely adopted to help securely run AI-generated code. E2B has raised $12M from investors including Decibel and Sunflower. In this episode, we dig into:Why agents need a sandboxBuilding a new category of infra tooling, much like LaunchDarkly Some of their viral content moments - including Greg Brockman sharing their videosFiguring out the right commercial offering Why they don't agree with pricing per token Why moving from Prague to the Bay Area felt essential for them as founders

Lukas Schulte is Co-Founder & CEO of SDF Labs, the developer platform that scales SQL understanding across organizations, which was recently acquired by data transformation unicorn dbt Labs. In this episode, he's joined by Anders Swanson, Senior Developer Experience Advocate at dbt, to discuss the acquisition and future of data engineering. In this episode, we dig into:How the acquisition happened, as well as the M&A process How dbt thinks about building capabilities internally vs. making acquisitions How the SDF platform will improve the lives of dbt users The most challenging parts about the integration What the future developer experience for data teams will be like A glimpse into the future of data engineering