Artificial intelligence (AI) and the discovery of novel antibiotics - with Jonathan Stokes

About this episode

Jonathan Stokes discusses the use of artificial intelligence in discovering novel antibiotics.

Jonathan Stokes and his colleagues are discovering novel antibiotics through artificial intelligence (AI) - among others Halicin and Abaucin. This AI-driven research was named one of the years top discoveries by The New York Times in 2023. Stay tuned for a very futuristic - and inspiring - interview with a very interesting researcher! References: Swanson, K., Liu, G., Catacutan, D.B.  et al.  Generative AI for designing and validating easily synthesizable and structurally novel antibiotics.  Nat Mach Intell   6 , 338–353 (2024). Lluka T, Stokes JM. Antibiotic discovery in the artificial intelligence era. Ann N Y Acad Sci. 2023 Jan;1519(1):74-93. doi: Liu G, Catacutan DB, Rathod K, Swanson K, Jin W, Mohammed JC, et al. Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii. Nature Chemical Biology. 2023;19(11):1342-50. Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, et al. A Deep Learning Approach to Antibiotic Discovery. Cell. 2020;180(4):688-702.e13. Awan RE, Zainab S, Yousuf FJ, Mughal S. AI-driven drug discovery: Exploring Abaucin as a promising treatment against multidrug-resistant Acinetobacter baumannii…

People in this episode

Host: Helse Bergen

Guest: Jonathan Stokes

Topics covered

• artificial intelligence
• antibiotic discovery
• novel antibiotics
• healthcare innovation
• research
• medicine

Keywords

• artificial intelligence
• antibiotics
• Halicin
• Abaucin
• drug discovery
• healthcare
• research

Mentioned in this episode

Organizations: The New York Times

Books & works: Generative AI for designing and validating easily synthesizable and structurally novel antibiotics, Antibiotic discovery in the artificial intelligence era, Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii, A Deep Learning Approach to Antibiotic Discovery, AI-driven drug discovery: Exploring Abaucin as a promising treatment against multidrug-resistant Acinetobacter baumannii, Halicin remains active against Staphylococcus aureus in biofilms grown on orthopaedically relevant substrates

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