RSI Trial Deep Dive

About this episode

The episode features a deep dive into the RSI trial, discussing its methodology, findings, and implications in critical care.

Special Guests: Matthew Semler, MD & Nicole Acquisto, PharmD, FASHP, FCCM, FCCP Join us as we do a deep dive into the RSI trial, published in NEJM in Dec 2025. Previous RCTs, study development timeline, guideline recommendations, study methodology and findings, answering listener questions, clearing up internet rumors, how to apply these findings, significant secondary outcome?, next steps, fun facts, and so much more. RSI Trial: https://pubmed.ncbi.nlm.nih.gov/41369227/ Episode Reference List: https://pharmacytodose.wordpress.com/wp-content/uploads/2026/01/rsi-trial-deep-dive-references.pdf @PharmacyToDose Pharmacytodose@gmail.com Pharmacytodose.com Learn more about your ad choices. Visit megaphone.fm/adchoices

People in this episode

Host: Nick Peters

Guests: Matthew Semler, MD, Nicole Acquisto, PharmD, FASHP, FCCM, FCCP

Topics covered

• RSI trial
• critical care
• study methodology
• guideline recommendations
• listener questions
• internet rumors
• secondary outcomes

Keywords

• RSI trial
• critical care
• NEJM
• study methodology
• guideline recommendations
• secondary outcomes
• listener questions

Mentioned in this episode

Organizations: NEJM, Pharmacytodose.com

Books & works: RSI trial, RSI Trial: https://pubmed.ncbi.nlm.nih.gov/41369227/, Episode Reference List

More episodes of Pharmacy to Dose: The Critical Care Podcast

• NSU Symposium Critical Care Clinical Pearls · February 17, 2026 · 1h 14m
• RSI Trial Bonus Episode · January 27, 2026 · 32 min
• 2025 ACCP Annual Meeting Recap · October 23, 2025 · 1h 32m
• 2025 ACCP Annual Meeting Highlights: FCCP Roundtable · October 21, 2025 · 39 min
• 2025 ACCP Annual Meeting Highlights: Elevating Clinical Pharmacy in the ICU · October 21, 2025 · 55 min
• 2025 ACCP Annual Meeting Highlights: NMBA & Ketamine · October 20, 2025 · 1h 5m