
Vagal Nerve Stimulation for Depression with Lucian Manu, MD
From Psychiatry Tomorrow by Osmind
November 5, 2025 · 46 min · Episode 28
About this episode
Dr. Lucian Manu discusses the benefits and processes of vagal nerve stimulation for treating treatment-resistant depression.
Vagal nerve stimulation (VNS) treats treatment-resistant depression with unique benefits: effects improve over 12-24 months, low relapse rates, and reduces ketamine frequency. Learn patient selection criteria, Medicare RECOVER trial access at 80+ sites, insurance appeals process, and how VNS creates a clinical "floor" preventing deepest episodes. Expert insights from Dr. Lucian Manu, Stony Brook University.
People in this episode
Guest: Lucian Manu, MD
Topics covered
- vagal nerve stimulation
- depression
- treatment-resistant depression
- Medicare RECOVER trial
- insurance appeals
- mental health
Keywords
- vagal nerve stimulation
- depression
- treatment-resistant
- Medicare
- insurance
- mental health
- ketamine
Mentioned in this episode
Organizations: Stony Brook University
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