10 Immutable Laws of Prescribing Estrogen

10 Immutable Laws of Prescribing Estrogen

From Purser Wellness by Purser Wellness by Dan Purser MD

April 14, 2026 · 21 min

About this episode

This episode explores the key benefits and guidelines for prescribing estrogen to women.

What are the MAIN benefits of Estrogen for Women? Let's take a deep dive into it! There are some do's and don'ts when it comes to estrogen benefits and prescription medications. 1. Estradiol (17B Estradiol) only. Why? Estriol isnot very breast friendly 2. Do not use Estriol or synthetics. Why? 3. BCP’s do NOT equal HRT 4. Oral Estradiol 1 mg or should be highly referredone. Topical – why? Top 3 killers in women – decreases MI, decreases strokes,decreased Type 2 Diabetes 5. There is no solid cause and effect or evidenceEstradiol causes breast cancer, HER2 ER increase. Having receptors does notincrease cause and effect – it is not the causation 6. Do not take orally if you have hypertension 7. Do not take orally if strong family history ofblood clots or pulmonary embolism 8. Do not take orally if you have Factor 5 Leiden 9. Do not take orally if you are outside the “Ten-YearWindow” – what is the “Ten-Year Window”? 10. Do not take if within 5 years of breastcancer, or if your oncologist says not too. Why? a. I don’t want my license being questioned b. I don’t want to get sued if some rare chance youget breast cancer. If you have any questions, visit my site at danpursermd.com or…

Topics covered

  • Estrogen
  • Women's Health
  • Hormone Replacement Therapy

Keywords

  • Estradiol
  • breast cancer
  • hypertension
  • blood clots
  • Ten-Year Window

Mentioned in this episode

Products: Estradiol

More episodes of Purser Wellness

Explore listener stats, chart rankings, contacts and more on the Purser Wellness podcast page.