MH | Neurobiology and Psycho Pharmacology
From STAT Stitch Deep Dive Podcast Beyond The Bedside by Regular Guy
June 11, 2026 · 58 min · Season 6 · Episode 7
About this episode
This episode discusses essential medications and safety red flags in neurobiology and psycho pharmacology.
The 20% That Matters Most: Must-Know Medications & Safety Red Flags Antipsychotics (for Schizophrenia/Psychosis) Extrapyramidal Symptoms (EPS): Include acute dystonia (severe muscle cramping/spasms), akathisia (intense internal restlessness), and pseudoparkinsonism. Priority action: Treat immediately with anticholinergics like benztropine (Cogentin) or diphenhydramine. Tardive Dyskinesia (TD): Irreversible involuntary movements (e.g., lip-smacking, tongue thrusting) caused by long-term use. Priority: Prevention and monitoring using the Abnormal Involuntary Movement Scale. Neuroleptic Malignant Syndrome (NMS): A rare, fatal idiosyncratic reaction. Red Flags: Extreme muscle rigidity, high fever, and autonomic instability (unstable blood pressure). Priority action: Stop the drug immediately and provide supportive medical care. Clozapine (Clozaril): An atypical antipsychotic that causes agranulocytosis (a life-threatening drop in white blood cells). Priority: Mandatory weekly WBC monitoring; immediately evaluate any signs of infection, such as a sore throat or fever. Metabolic Syndrome: Atypical antipsychotics frequently cause severe weight gain, diabetes, and hyperlipidemia…
People in this episode
Host: Regular Guy
Topics covered
- neurobiology
- psycho pharmacology
- antipsychotics
- medication safety
- mental health
Keywords
- antipsychotics
- Clozapine
- metabolic syndrome
- suicide risk
- treatment safety
Mentioned in this episode
Organizations: Abnormal Involuntary Movement Scale
Products: benztropine, diphenhydramine, Clozaril, SSRIs, SNRIs, TCAs, MAOIs
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