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Est. listeners per new episode within ~30 days
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Ep. 107: Sid Sijbrandij On Beating Cancer with First Principles, n = 1 Personalized Treatments and Special Access Regulatory Pathways
Apr 10, 2026
47m 22s
Ep. 106: Yaron Brook: Capitalism, Ayn Rand, and the Moral Case for Freedom
Mar 18, 2026
1h 12m 53s
Ep. 105: Andrew Hessel: Programming DNA and Engineering the Future of Life
Feb 20, 2026
1h 05m 42s
Ep. 104: Ruxandra Teslo: Clinical Trials, Drug Innovation, and the Bottleneck to Biotech Abundance
Feb 20, 2026
1h 02m 38s
Ep. 103: Ian Huyett on Right to Try, Christian Techno Optimism, and Biotech Federalism
Dec 17, 2025
1h 03m 20s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 4/10/26 | ![]() Ep. 107: Sid Sijbrandij On Beating Cancer with First Principles, n = 1 Personalized Treatments and Special Access Regulatory Pathways✨ | cancer treatmentpersonalized medicine+3 | Sid Sijbrandij | GitLabInfinita City | — | cancerpersonalized treatments+4 | — | 47m 22s | |
| 3/18/26 | ![]() Ep. 106: Yaron Brook: Capitalism, Ayn Rand, and the Moral Case for Freedom✨ | capitalismAyn Rand+5 | Yaron Brook | Ayn Rand InstituteYaron Brook Show | — | capitalismAyn Rand+5 | — | 1h 12m 53s | |
| 2/20/26 | ![]() Ep. 105: Andrew Hessel: Programming DNA and Engineering the Future of Life✨ | genome sequencingDNA synthesis+5 | Andrew Hessel | Infinita CityCRISPR | — | DNAgenome writing+5 | — | 1h 05m 42s | |
| 2/20/26 | ![]() Ep. 104: Ruxandra Teslo: Clinical Trials, Drug Innovation, and the Bottleneck to Biotech Abundance✨ | drug developmentclinical trials+4 | Ruxandra Teslo | FDA | AustraliaChina | drug innovationclinical trials+5 | — | 1h 02m 38s | |
| 12/17/25 | ![]() Ep. 103: Ian Huyett on Right to Try, Christian Techno Optimism, and Biotech Federalism✨ | Right to TryChristian Techno Optimism+4 | Ian Huyett | CornerstoneThe Christian War on Death | New HampshireMontana+1 | Right to Trybiotech+6 | — | 1h 03m 20s | |
| 11/28/25 | ![]() Ep. 102: Arjun Khemani: Zcash, Radical Privacy, and the New Renaissance✨ | cryptographyprivacy+5 | Arjun Khemani | ZcashBitcoin+2 | — | ZcashBitcoin+8 | — | 57m 46s | |
| 11/14/25 | ![]() Ep. 101: Bryan Caplan: Pro Market & Pro Business, the Real Ethics of Entrepreneurship✨ | free marketsentrepreneurship+4 | Bryan Caplan | George Mason UniversityMicrosoft+3 | — | entrepreneurshipfree markets+7 | — | 1h 05m 41s | |
| 10/31/25 | ![]() Ep. 100: A Conversation with Dr. Mary Ruwart: The Lost Innovation Cost of the FDA, and How Founders Can Reclaim the Right to Build✨ | FDA regulationspharmaceutical innovation+4 | Dr. Mary Ruwart | FDABig Pharma+1 | MontanaPróspera | FDAinnovation+7 | — | 1h 17m 21s | |
| 9/23/25 | ![]() Ep. 99: A Conversation with Cremieux - How to Tell Good Science from Junk, and What’s Next in US Biotech & Deregulation✨ | biotechscience+4 | Cremieux | FDAInfinita City+5 | — | p-hackingoutcome switching+6 | — | 1h 07m 52s | |
| 9/12/25 | ![]() Ep. 98: A Conversation with Adam Thierer: The War on Computation - Why AI Must Stay Permissionless✨ | AI regulationinnovation+4 | Adam Thierer | Infinita CityPermissionless Innovation+1 | — | AIregulation+5 | — | 55m 48s | |
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| 8/29/25 | ![]() Ep. 97: Dr. Michael Levin on Bioelectricity, Anthrobots, and the Software of Life | In this episode, Michael Levin, Director of the Allen Discovery Center at Tufts, breaks down how his lab is rethinking regeneration, cancer, and aging, not through genetics, but through bioelectricity as the software of life.From pioneering living robots made from frog skin cells to repairing birth defects and regenerating limbs, Levin’s work shows how tissues act as intelligent agents and how future medicine will be about communicating goals to cells, not micromanaging their chemistry.We cover:* Why Levin believes the “anatomical compiler” is the endgame: designing an organ or organism on a computer and compiling it into bioelectric instructions for cells.* How cancer emerges as a breakdown of collective memory and why reconnecting cells electrically can normalize tumors without killing them.* Proof-of-concept experiments that restore normal brains in tadpoles with birth defect mutations, regenerate frog legs, and even grow functioning eyes in new locations.* The creation of Anthrobots, synthetic multicellular organisms built from adult human cells that can repair neural damage.* Why development and regeneration show that genomes don’t dictate fixed outcomes bioelectric memories do.* The philosophical implications: recognizing agency and intelligence at every level of biology.If you’re building in biotech, longevity, or frontier medicine, this is a field guide to rewriting the software of life and a preview of the systems that could make aging, cancer, and trauma solvable problems.More about Michael Levin’s work:* Dr. Michael Levin's X* Dr. Michael Levin WebsiteExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 01m 18s | ||||||
| 8/14/25 | ![]() Ep. 96: Digital Nomads’ Individual Sovereignty and Regulatory Hacking in International Insurance Markets - A Conversation with SafetyWing CEO Sondre Rasch | In this episode, Sondre Rasch, founder & CEO of SafetyWing, breaks down how his team is building global health insurance and infrastructure for digital nomads, and what it takes to operate in one of the most regulated industries in the world.* From policy advisor in the Norwegian government to a $50M revenue insurance company* The legal and regulatory hacks that let SafetyWing serve nomads across 180+ countries* Why differentiated products can thrive where generic ones die, even under heavy regulation* The hidden traps of “innovation labs” and how to actually partner with insurers* How SafetyWing’s Nomad Citizen program is taking first steps toward an “internet country”* How SafetyWing is the “oddly mature company” within the network state communityIf you’re building in insurance, frontier tech, or the network state space, this is a field guide to turning regulatory complexity into a moat — and building systems that outlive any single jurisdiction.More about Sondre’s work:* Sondre’s X* Safety WingExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 03m 39s | ||||||
| 7/17/25 | ![]() Ep. 95: The Philosophical Implications of Radical Life Extension - A Conversation with John Martin Fischer | John Martin Fischer is Distinguished Professor of Philosophy at UC Riverside and a leading thinker on death, free will, and immortality. He joins Niklas to explore:* Why most philosophers argue against immortality and why he disagrees* The logic behind boredom, meaning, and the “human shape” of life* How AI and free will intersect and what it means for future minds* Ethical blind spots in Silicon Valley’s pursuit of radical life extensionStranded Technologies Podcast is the channel for the Infinita community, dedicated to accelerating longevity biotech and building the future of innovation-friendly cities.More about GUEST'S work:* John Martin Fischer WebsiteExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 01m 12s | ||||||
| 7/4/25 | ![]() Ep. 94: Jose Luis “Nintil” Ricón on Metascience, Longevity Biotech Pathways and Parallel Institutions | Jose Luis Ricón Fernández de la Puente is widely known for his influential blog “Nintil” and in his current role as Head of Theory at Retro Biosciences, a leading company in the longevity biotech space funded with $180m by Sam Altman. Niklas and Jose Luis dive into:* Why the current scientific institutions often fail to deliver on its promises* The most promising pathways and bottlenecks in longevity biotech* Lessons from libertarianism and economics for building better scientific institutions* The role of network cities, special jurisdictions, and parallel systemsStranded Technologies Podcast is the channel for the Infinita community, dedicated to accelerating longevity biotech and building the future of innovation-friendly cities.More about GUEST'S work:* Retro.bio* Nintil This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 12m 50s | ||||||
| 4/10/25 | ![]() Ep. 93: Cush on Latin American Dynamism, Crypto Adoption, and Building Subcultures of Relentless Ambition | Cush is the founder of Odisea Labs, an accelerator for Latin American frontier tech (crypto, AI). Cush is inspired by effective accelerationism (e/acc) and consequently coined the memes “latam/acc” and “Latin American Dynamism” in reference to their US-based counterpart.In this episode, we learn all about why Latam is awesome for tech. Financial innovation and crypto have a fertile ground here and are widely adopted due the lack of banking access for large populations, regulatory capture and government mismanagement.Odisea Labs has been a major partner to the past March Startup Residency Month, and is now announcing another partnership with Infinita City for the following:Crypto Cities Theme MonthThis is a one-month program for builders to deploy crypto-native projects, not just online, but in a functioning city with enabling legislation, crypto taxes, and a supportive community.🗓️ | June 1 - 30, 2025📍 | Próspera Zone, Roatan (Honduras)➡️ | Signup: infinita.city/crypto-cities This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 00m 33s | ||||||
| 3/28/25 | ![]() Ep. 92: Jack Scannell On Eroom’s Law In Drug Development | Jack Scannell is a consultant, researcher, and entrepreneur. Jack is one of the world’s leading authorities on pharmaceutical R&D productivity. He co-authored the influential 2012 paper in Nature Reviews Drug Discovery that introduced “Eroom’s Law,” a concept highlighting how drug discovery has become slower and more expensive over time—essentially the opposite of Moore’s Law. Scannell has advised major pharmaceutical firms and is a noted commentator on strategies to improve innovation efficiency in the life sciences. He is currently building Ethereos.Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 45m 55s | ||||||
| 3/19/25 | ![]() Ep. 91: JP Vergne on the Pirate Organization as the Innovators of Capitalism and Governance | Jean-Philippe (JP) Vergne is an Associate Professor of Strategy at Western University’s Ivey Business School, renowned for his research on organizations operating at the fringes of legality—particularly pirates. Along with Rodolphe Durand, he co-authored The Pirate Organization: Lessons from the Fringes of Capitalism, which explores how historical piracy and other unconventional ventures can shed light on modern forms of competition, regulation, and innovation. JP Vergne’s work extends to topics such as crypto governance, the historical development of organizations, and the evolution of capitalism.Book Reference: The Pirate Organization: Lessons from the Fringes of CapitalismExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 16m 50s | ||||||
| 2/19/25 | ![]() Ep. 90: Unlimited Bio’s Journey to Launch a Prospera Biotech Company - with Ivan Morgunov & Dr. Anna Vakhrusheva | Ivan Morgunov is an experienced entrepreneur driven by the goal of stopping aging. He founded Longaevus Technologies, a venture studio in the field of longevity, and Unlimited Bio—one of the two companies that administer genetic therapies in Prospera Dr. Anna Vakhrusheva has over a decade of experience in advancing vaccines and gene therapies. She led the development of Russia’s first recombinant SARS-CoV-2 vaccine (Betuvax JSC), driving it from R&D to clinical trials within two years. As a co-founder of Unlimited Bio, she spearheads genetic therapy research, translating cutting-edge science into real-world longevity solutions.In this episode, Anna & Ivan describe their journey to start a biotech company in Prospera, their novel thesis on why business model innovation matters to solve aging, the opportunity of “cocktail therapies”, regulatory fast-track options and challenges in a new jurisdiction.Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 04m 11s | ||||||
| 2/13/25 | ![]() Ep. 89: Nathan Cheng On His Journey To Radical Life Extension, The LBF Roadmap To Solve Aging, and The Role Of Ideology | Nathan Cheng is a community builder, educator, and investor in the longevity biotech field. He has been closely involved with key initiatives such as the Longevity Biotech Fellowship (LBF), Healthspan Capital, and Longevity List, working to solve the problem of aging and death.In this conversation, Nathan Cheng discusses his journey into the longevity biotech field, exploring the quest for an indefinite lifespan and the various strategies to combat aging. He shares insights on community building, the importance of understanding aging, and the potential of biotechnology in extending life. The conversation also delves into the technical roadmap for solving aging, replacement strategies, and the role of cryonics as a last resort. In this conversation, Nathan Chang and Niklas Anzinger discuss the importance of mission-driven research in the field of longevity, emphasizing the need for focused efforts to tackle aging and death. They explore the role of the Longevity Biotech Fellowship in mobilizing talent and fostering collaboration among diverse professionals. The discussion also touches on effective communication strategies for the longevity mission, the catalysts for progress in the field, and the opportunities for newcomers to enter the longevity space. Finally, they introduce the Vitalism Foundation, which aims to unify efforts in the longevity movement under a shared ideology.Get involved & More about Nathan's work:* Longevity Biotech Fellowship (10% off for Infinitians)* Vitalist Bay (10% off for Infinitians)* Vitalism FoundationExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 03m 07s | ||||||
| 1/29/25 | ![]() Ep. 88: Samo Burja on Great Founders, Institutional Change and the Fragility of Technological Progress | Samo Burja is a researcher, strategist, and founder of Bismarck Analysis and on the editorial board of Palladium Magazine. Samo is known for his work on how institutions shape civilization and his book “The Great Founder Theory.”Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 13m 31s | ||||||
| 1/22/25 | ![]() Ep. 87: Terence Kealey - Decentralized Science, Neo-Medieval Universities & Longevity Moonshots | Terence is a British biochemist who was Vice-Chancellor of the University of Buckingham, Adjunct Scholar at the Cato Institute, and the author of numerous books.Terence is well-known for his case against government funding of science, which made him an influence in the decentralized science movement. We’ll talk about his views on the economics of science and the myth of scientific objectivity. Importantly, we’ll talk about something that Terence has never talked about in public. A new project that aims to do it better.This new project will take place within the next Infinita Forever Pop-Up City—a new school and research center on the island of Roatan, with a neo-medieval form of governance.Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 07m 48s | ||||||
| 1/15/25 | ![]() Ep. 86: Anders Sandberg on Meta-Innovation, Governance Futurism and Approaches to Existential Risk | Our guest is Anders Sandberg. Anders is a Swedish researcher, futurist and transhumanist. He holds a PhD in computational neuroscience from Stockholm University, and is a former senior research fellow at the Future of Humanity Institute at the University of Oxford.This conversation is about the governance of innovation, and the innovation of governance. Explore Infinita City:* Website: www.infinita.city* X: @InfinitaCity* The Infinita City Times* Join Events This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 1h 14m 17s | ||||||
| 9/20/24 | ![]() Ep. 85: Brian Armstrong On Accelerating Civilizational Progress Through Crypto And Longevity | Brian is the Co-founder and CEO of Coinbase; he began his journey studying computer science and economics. Back early in his career, after a trip to Argentina and seeing hyperinflation, he was inspired by Bitcoin’s potential to update the financial system and increase economic freedom in the world.He started Coinbase in 2012, and by 2021, it had become a public company worth $50B by 2024.Post-IPO, he started thinking about longevity; he started organizing biotech dinners to explore innovative ideas. And this led him to found NewLimit, a company focused on epigenetic reprogramming to combat aging, utilizing machine learning to discover potential treatments.In this Fireside Chat, Brian discusses his vision for crypto and longevity with Niklas Anzinger, Vitalia's CEO, and Erick Brimen, Próspera's CEO. The conversation happened in the special economic zone of Próspera on the island of Roatán in Honduras. With a common law-based, pro-liberty legal system that is probably the most crypto-friendly in the world.In this special zone, Vitalia has started to build a community of longevity enthusiasts, crypto natives and biotech founders - taking advantage of expedited clinical trials and medical reciprocity laws that allow access to treatments approved in 30+ countries.Crypto Cities In The Real WorldBrian and the team of Coinbase Ventures visited Próspera and Vitalia to explore the possibilities for real-world crypto adoption, and how it can solve humanities’ biggest challenges. There are several existing uses and enormous opportunities for crypto to build real cities.That is why, we're excited to introduce –Crypto Cities Builders' Program (Oct 19 - Nov 19)We’re inviting crypto/web3 builders & founders to join us in Vitalia’s Roatán Hub, to build real solutions or accelerate your existing startups & projects.→ https://vitalia.city/cryptocitybuildersMore about Brian's work:* https://www.brianarmstrong.org/* https://www.coinbase.com/* https://www.newlimit.com/ This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 55m 34s | ||||||
| 8/16/24 | ![]() Ep. 84: Joe Lonsdale On How To Fix Broken Institutions | In this conversation, we're discussing with Joe Lonsdale the potential for building new cities and network states to improve governance in countries with broken institutions.Joe Lonsdale is a technology entrepreneur and investor. He is the managing partner at 8VC, a multi-billion dollar firm in the US. Previously he co-founded Palantir.Agencies and institutions are broken. The SEC on the fight with crypto, the FDA on the battle to bring needed drugs to market, and the FTC on not allowing companies to be acquired and merged to grow into something bigger. Joe encourages entrepreneurs to identify the biggest gaps in areas hindered by regulatory constraints, such as transportation, infrastructure, immigration, or biotech, and aggressively pursue solutions.Successful examples abroad can inspire change in the US. Like what's happening in Vitalia City within the Próspera special economic zone in Honduras, this approach can demonstrate effective solutions, encouraging the U.S. to adopt these innovations and improve its systems."Building a great city-state would help the US, just as Singapore helps China a lot. We can have another Hong Kong or Singapore of the Americas."More about Joe's work:* joelonsdale.com* Cicero Institute* 8VCIf you liked this episode, please consider supporting the “Stranded Technologies” publication (podcast + blog) to make it possible for us to make high-quality material. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 29m 37s | ||||||
| 5/7/24 | ![]() Ep. 83: Bradley Tusk – The Uber Story, Applying Political Leverage, and Practical Advice For Entrepreneurs On How To Overcome Regulatory Roadblocks | Bradley Tusk is a cofounder of Tusk Venture Partners, which invests in early-stage technology companies operating in highly regulated industries.Bradley was also Uber's first political advisor and instrumental in developing their strategy to disrupt the incumbent taxi monopolies.This is one of the most fascinating stories in the recent history of regulatory hacking.In this episode, we're demystifying political misconceptions and looking into practical advice for entrepreneurs on navigating regulatory roadblocks and changing them for their benefit.Key Takeaways:* Every policy output is the result of political input. Every politician makes every decision solely based on reelection and nothing else.* The vast majority of companies are regulated in some way. Rather than avoid dealing with regulations, run with the mindset that you'll figure it out. * To hack the regulatory system, you need to take into consideration that:* 1) The level of government really matters—focus on doing things on a local or state level rather than a federal level;* 2) Get your customers to advocate for you More about Bradley's work:* bradleytusk.com* Tusk Venture Partners* Podcast – Firewall* Book – The Fixer: My Adventures Saving Startups from Death by Politics This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com | 52m 42s | ||||||
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