Cholesterol Debate: What Would Falsify the Lipid Hypothesis? – TFP #019 | Josh Wageman PhD

About this episode

The episode explores the relationship between cholesterol and cardiovascular risk with guest Josh Wageman, emphasizing the importance of context and communication in understanding lipid health.

In this episode of The Feldman Protocol, a provocative question anchors the conversation: how much of cardiovascular risk is about cholesterol itself versus the context it operates in? Guest **Josh Wageman, DPT, PA-C, PhD**—a clinical lipid specialist and researcher—makes the case for using metaphor, metabolic health, and imaging to think differently about risk. The discussion spans coronary calcium scoring, lipid particles, insulin and inflammation, endurance training extremes, neurodegeneration, and why communicating science clearly actually matters. 🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/sp/19 Private blood testing services 🩸Over 300 blood tests 💰 Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:00 – Why metaphors matter in…

People in this episode

Host: Dave Feldman

Guest: Josh Wageman

Topics covered

• cholesterol
• cardiovascular risk
• metabolic health
• lipid particles
• neurodegeneration

Keywords

• cholesterol
• lipid hypothesis
• cardiovascular risk
• metabolic health
• coronary calcium scoring

Sponsors

Own Your Labs

More episodes of The Feldman Protocol

• Chris Masterjohn PhD – Seed Oils, LDL & Mitochondria | TFP #035 · June 11, 2026 · 3h 0m
• Animal Protein vs Plant Protein — The Amino Acid Truth – Peter Ballerstedt PhD | TFP #034 · June 8, 2026 · 3h 21m
• Tommy Wood MD PhD: Brain Health, CTE & Dementia Risk – TFP #033 · June 7, 2026 · 2h 59m
• Shawn Baker MD – Why Carnivore Fixed What Keto Alone Couldn't – TFP #032 · May 26, 2026 · 3h 16m
• How Robert Sikes Was Eating 70g of Fat Backstage to Win a Bodybuilding Competition – TFP #031 · May 22, 2026 · 2h 19m
• Nick Norwitz Has Total Cholesterol of 700 — So Why Zero Plaque? – TFP #030 | Nick Norwitz MD PhD · May 15, 2026 · 1h 39m