Aleksander Krag on the utility of PEth for subclassifying individuals at risk of steatotic liver disease

Aleksander Krag on the utility of PEth for subclassifying individuals at risk of steatotic liver disease

From The Lancet Gastroenterology & Hepatology in conversation with by The Lancet Group

February 23, 2026 · 20 min

About this episode

Aleksander Krag discusses the use of PEth as a biomarker for subclassifying individuals at risk of steatotic liver disease.

Steatotic liver disease labels hinge on alcohol intake, but self-report is often inaccurate. In this episode, Aleksander Krag (Odense University Hospital) discusses a large Danish study using phosphatidylethanol (PEth), a direct blood biomarker of recent drinking, showing substantial underestimation and potential reclassification from MASLD to MetALD/ALD. Click here to read the full article: https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00187-6/fulltext Medical imaging an...

People in this episode

Guest: Aleksander Krag

Topics covered

  • steatotic liver disease
  • alcohol intake
  • biomarkers
  • health research
  • medical imaging

Keywords

  • steatotic liver disease
  • PEth
  • alcohol consumption
  • biomarker
  • Danish study

Mentioned in this episode

Organizations: Odense University Hospital, The Lancet

Books & works: phosphatidylethanol (PEth)

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