Dr. Matt Ranks Longevity Supplements: The Winners and Total Scams
From The Optispan Podcast with Matt Kaeberlein by Optispan
February 15, 2026 · 36 min
About this episode
Matt Kaeberlein evaluates 13 popular longevity supplements, distinguishing between effective products and scams.
The longevity supplement industry is full of hype, marketing claims, and questionable science. In this episode, Matt breaks down 13 popular supplements through an evidence-based lens.Subscribe for more evidence-based longevity content. Timestamps:0:00 - Introduction: 13 Supplements Ranked, 1:41 - How the Tier List Works (Strong, Good, Promising, Overhyped, Avoid), 2:27 - Fucoidin, 8:04 - Fisetin, 8:54 - Lithium Orotate, 12:34 - Resveratrol, 13:24 - Creatine, 14:58 - CoQ10, 15:53 - SS Peptides (SS-31/Elamipretide), 24:09 - Proprietary "Anti-Aging" Blends, 24:55 - NAD+ Precursors, 27:17 - Omega-328:47 - Vitamin D, 29:24 - Fatty 15 (Pentadecanoic Acid), 31:01 - Urolithin A, 32:31 - Final Rankings: All 13 Supplements Ranked 1-13, 34:41 - Closing Thoughts
People in this episode
Host: Matt Kaeberlein
Topics covered
- longevity supplements
- evidence-based analysis
- health claims
- supplement ranking
- anti-aging
Keywords
- longevity
- supplements
- evidence-based
- health
- anti-aging
- ranking
- nutrition
Mentioned in this episode
Products: Fucoidin, Fisetin, Lithium Orotate, Resveratrol, Creatine, CoQ10, SS Peptides (SS-31/Elamipretide), NAD+ Precursors, Omega-3, Vitamin D
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