498 | Dr. Kyle Gillett | Optimizing Testosterone: Interpreting Labs and Choosing the Right Treatment

About this episode

Dr. Kyle Gillett joins Dr. Erin to discuss testosterone regulation and treatment options.

Dr. Kyle Gillett joins Dr. Erin to break down the physiology behind testosterone regulation, including how SHBG, free versus total testosterone, and androgen receptor sensitivity influence symptoms, metabolic health, and treatment decisions. They discuss why men with similar lab values can feel very different, how lifestyle and insulin resistance affect hormone metabolism, and when tools like TRT or aromatase inhibitors are actually warranted. This episode focuses on practical, evidence-based mechanisms that help patients and clinicians make informed choices about hormone optimization

People in this episode

Host: Dr. Erin

Guest: Dr. Kyle Gillett

Topics covered

• testosterone regulation
• hormone optimization
• metabolic health
• TRT
• androgen receptor sensitivity

Keywords

• testosterone
• SHBG
• free testosterone
• total testosterone
• insulin resistance
• hormone metabolism
• TRT
• aromatase inhibitors

Mentioned in this episode

Organizations: Wild Health

More episodes of Wild Health Podcast

• 502 | Dr. Sahil Chopra | How We Can Identify Health Risk Through Sleep Before Symptoms Appear · January 7, 2026 · 51 min
• 501 | Dr. James Min | How We Can Detect Heart Disease Before Symptoms Appear · December 17, 2025 · 51 min
• 500 | Steve Weatherholt | Raising Your VO2 Max for Longevity and Performance · December 10, 2025 · 53 min
• 499 | Dr. Michael Snyder | Using Glucose Phenotypes to Personalize Type 2 Diabetes Care · December 3, 2025 · 39 min
• 497 | Dr. Damon Forbes | Understanding Lipoprotein(a) and Cardiovascular Risk · November 19, 2025 · 52 min
• 496 | Ashleigh Di Lello | Rewiring the Nervous System for Healing and Resilience · November 12, 2025 · 57 min