The Science Behind MIEBOⓇ (perfluorohexyloctane ophthalmic solution)

About this episode

This episode explores the complexities of dry eye disease and the unique properties of MIEBO in managing tear evaporation.

Understanding the Complexity of Dry Eye Disease Historically, dry eye disease (DED) was oversimplified, often attributed solely to aqueous tear deficiency. However, research shows that approximately 86% of DED cases involve an evaporative component, where the tear film loses stability, leading to faster tear evaporation. This can be due to many factors, including meibomian gland dysfunction, prolonged screen time, and environmental influences. As professor and optometrist Dr. Chris Lievens explains, “Dry eye sounds so basic—if it’s dry, make it wet. But actually, the science is incredibly complex.” Today’s comprehensive approach to DED considers various aspects of the tear film, including the mucin, aqueous, and lipid layers. It’s the evaporative aspect that MIEBO targets, making it a unique and essential addition to dry eye management. The Science Behind MIEBO MIEBO is the only Rx eye drop for DED that directly targets tear evaporation. Its active and only ingredient, perfluorohexyloctane forms a protective layer on the eye’s surface. The dual properties of this molecule—aerophilic (high affinity for air) and lipophilic (high affinity for fats/oils)—allow it to form a…

Topics covered

• Dry Eye Disease
• Tear Film
• MIEBO
• Evaporative Component
• Meibomian Gland Dysfunction

Keywords

• dry eye disease
• MIEBO
• perfluorohexyloctane
• tear evaporation
• meibomian gland dysfunction

Mentioned in this episode

Products: MIEBO, perfluorohexyloctane

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