Discover CircRes

This month on Episode 85 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the May 22nd, June 5th and June 19th issues of Circulation Research. This Episode also features a discussion with Professor Katrin Schäfer, Dr Rajinikanth Gogiraju, and Dr Beichen Sun, about their study, Chronic Erythrocyte NO Production Accelerates Atherosclerosis by Increasing SMC De Novo Lipogenesis. Article highlights: Larcher, et al. Cardiac Fibroblast Heterogeneity and Disease Huang, et al. Vascular Endothelial NOX1 Drives Obesity Atici, et al. Role of Sirtuin-1 in Murine Vasculitis Compendium on Lipoproteins and Cardiovascular Disease

This month on Episode 73 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the May 23rd and June 6th issues of Circulation Research. This Episode also includes a discussion with Dr Jae Min Cho and Tzung Hsiai, about their study, Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness. Article highlights: Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases: A Compendium He, et al. NEP in Placental EVs Triggers Hypertension in PE Dennis, et al. FoxO1-zDHHC4-CD36 S-Acylation Axis in Diabetes

This month on Episode 71 of Discover CircRes, host Cindy St. Hilaire highlights three articles featured in the March 28th and April 11th issues of Circulation Research. This Episode also includes a discussion with Dr Magali Noval Rivas and Dr Prasant Jena from Cedars-Sinai Medical Center about their study, Intestinal Microbiota Contributes to the Development of Cardiovascular Inflammation and Vascular in Mice. Article highlights: Han, et al. PRL2 Dephosphorylates AMPKα2 in Heart Perelli, et al. TAX1BP3 and Arrhythmogenic Cardiomyopathy Lalaguna, et al. Overexpression of Wild Type TMEM43 Improves ARVC5 Liu, et al. NR4A1 Inhibits Platelet Function

This month on Episode 69 of Discover CircRes, host Cindy St. Hilaire highlights four articles featured in the January 31st and February 14th issues of Circulation Research. This Episode also includes a discussion with Dr Frank Conlon and graduate student Ike Emerson about their study, X Chromosome-Linked MicroRNAs Regulate Sex Differences in Cardiac Physiology. Article highlights: Huang, et al. Vps4a Safeguards Plasma Membrane Integrity Liu, et al. PPM1B Deubiquitination Promotes Arterial Stiffness Muralitharan, et al. GPR41/43 and Blood Pressure Park, et al. Ferroptosis and Its Consequences in Preeclampsia

This month on Episode 67 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the December 6th issues of Circulation Research. This Episode also includes a discussion with Drs Jesse Rowley and Shancy Jacob about their study, Mitofusin-2 Regulates Platelet Mitochondria and Function. Article highlights: Bardhan, et al. Sex Specific Roles of Microbiota in Hypertension Ma, et al. Kindlin-2 LLPS Controls Vascular Stability Wang, et al. CAR-Ms Alleviate Myocardial I/R Injury

This month on Episode 65 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the September 27th and October 11th issues of Circulation Research. This Episode also includes a discussion with Dr Ken Walsh and Dr Ariel Polizio about their study, Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism. Article highlights: Ju, et al. NAE1 Crotonylation Regulates Cardiac Hypertrophy Pirri, et al. EPAS1 Atheroprotection via Fatty Acid Metabolism Saleem, et al. Myeloid CD11c+ Cells and JAK2/STAT3/SMAD3 in SSBP Pietsch, et al. Chronic Activation of Tubulin Tyrosination

This month on Episode 63 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 2nd and August 16th issues of Circulation Research. This Episode also includes a discussion with Drs Chen Gao and Yibin Wang about their study, Glucagon Receptor Antagonist for Heart Failure with Preserved Ejection Fraction Article highlights: Douvdevany, et al. Imaging the Turnover of the Sarcomere Quelquejay, et al. Wnk1 Deletion in Smooth Muscle Cells Induces Aortitis Paulke, et al. The Role of Dysferlin in Cardiac Hypertrophy Morais, et al. Predictors of Outcome in SPAN

This month on Episode 61 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the June 7th and June 21st issues of Circulation Research. This Episode also includes a discussion with Dr Chris O'Callaghan and Jiahao Jiang from the University of Oxford about their study, A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease. Article highlights: Compendium on Interface Between Cardioimmunology, Myocardial Health, and Disease Zafeiropoulo, et al. Splenic Ultrasound Improves Pulmonary Hypertension Roman, et al. MICU3 Enhances Mitochondrial Ca2+ Uptake