Chasing Goals, Not Ghosts: Mireille Siné on Running 200 Miles with Lupus

About this episode

Mireille Siné shares her journey of overcoming lupus to achieve remarkable running milestones and discusses training strategies for autoimmune athletes.

Lupus put her in the ICU in college. She came back to run 14 marathons, 5 ultras, and 200 miles from Boston to NYC. Run coach Mireille Siné on training with autoimmune disease — flares , fatigue , and the mindset shift that changes everything . In this episode of Invisible Strength, Karin and Chris talk with Mireille Siné — certified run coach, AIP nutrition coach, and the first Black woman to run 200 miles from Boston to New York City. Mireille shares her full story: the college stress that preceded her lupus diagnosis, the blood clot that took three ER visits to catch, chemotherapy and medical leave, and the slow, deliberate comeback that started with a quarter-mile run. We get practical: how Mireille structures training around flares with her stoplight protocol, why sleep is her non-negotiable recovery anchor, how she approaches nutrition and meal prep for inflammation, and how to tell normal training fatigue from the start of a flare. Plus the mental game — why "you're not gonna get anywhere chasing a ghost," and what invisible strength means to her. ✨ FREE QUIZ: Not sure where to start on your own health journey? Take our free quiz →…

People in this episode

Hosts: Karin Wagner, Chris Burton

Guest: Mireille Siné

Topics covered

• running
• autoimmune disease
• marathon training
• nutrition
• mental health
• coaching

Keywords

• lupus
• marathons
• ultras
• training
• nutrition
• recovery
• mental game
• autoimmune

Mentioned in this episode

Organizations: AIP

Places: Boston, New York City

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