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Recent episodes
Is Ezetimibe the Secret to Preventing Dementia? Surgeon Reacts to Nick Norwitz MDPhD
May 11, 2026
42m 40s
Is Lower LDL Actually Better? New Research Has an Answer
May 4, 2026
23m 59s
The Truth About Aspirin and Heart Attack Prevention
Apr 27, 2026
24m 15s
Ask Me (Almost) Anything With Dr Johnston | Live Q&A
Apr 20, 2026
1h 42m 55s
Can You Unclog Arteries? A Vascular Surgeon Reacts to Dr Kevin Ham
Apr 13, 2026
20m 42s
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| Date | Episode | Description | Length | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 5/11/26 | Is Ezetimibe the Secret to Preventing Dementia? Surgeon Reacts to Nick Norwitz MDPhD | A common cholesterol drug might protect your brain from Alzheimer's — but I read the actual study, and there's a red flag nobody is talking about. Nick Norwitz covered this story. I went further — I pulled the original paper published in Aging Biology and read every line. Here's what I found.Researchers ran a hypothesis-free screen of FDA-approved drugs to find compounds that could disrupt the 14-3-3/hexokinase protein interaction — a mechanism implicated in the protein aggregation that driv... | 42m 40s | ||||||
| 5/4/26 | Is Lower LDL Actually Better? New Research Has an Answer | Is lower LDL cholesterol actually better for your heart? In this video, I break down the brand-new results from the EZ-Pave study to answer the question that keeps my patients up at night: How low should your cholesterol really go? As a vascular surgeon, I see the end-stage results of heart disease every day. We’ve heard the "lower is better" mantra for decades, but new research is finally providing the hard evidence we need to settle the debate. Study link: https://www.n... | 23m 59s | ||||||
| 4/27/26 | The Truth About Aspirin and Heart Attack Prevention | I've seen daily aspirin save lives from heart attack — and cause fatal bleeds. As a vascular surgeon, here's my honest take on heart health. The answer isn't yes or no — it depends entirely on who you are. In this video I break down the three groups you need to know: ✅ Who SHOULD take daily aspirin — if you've already had a heart attack, stroke, or stent, aspirin for secondary prevention of heart disease is still one of the most evidence-backed interventions we have. ❌ Who SHOULD NOT — th... | 24m 15s | ||||||
| 4/20/26 | Ask Me (Almost) Anything With Dr Johnston | Live Q&A | We hit all the high points today! Nutrition, exercise, lipids, dental health, hormones, and more. We had amazing participation and it was wonderful to have a chance to interact with everyone in real time. Thanks SO much for taking some of your precious weekend to talk cardiovascular health, heart scans, CAC scores, and all the other nerdy prevention things with me. Hope you enjoyed it! If you want me to do more of these in the future, please say so in the comments! Water filters that remove ... | 1h 42m 55s | ||||||
| 4/13/26 | Can You Unclog Arteries? A Vascular Surgeon Reacts to Dr Kevin Ham | Plaque reversal is one of the most debated topics in preventive cardiology, so in this video I react to Dr. Kevin Ham’s CAST protocol for plaque reversal: Causes, Adding Cures, Strengthening the Body, and Training the Mind and Body. Overall, I think this is a thoughtful framework and I agree with much of it. But as a vascular surgeon who treats advanced atherosclerosis, I also add some nuance around what “plaque reversal” really means, what may be missing from this conversation, and where I’... | 20m 42s | ||||||
| 4/13/26 | I'm a Vascular Surgeon — Stop Getting Repeat CAC Scans. Here's Why | If you’ve had a positive calcium score (CAC score), you’ve probably asked the obvious next question: when should I repeat it? In this video, I explain why I generally do not order another calcium score if the first one is positive—and what I prefer to use instead to follow atherosclerosis over time. We walk through what a coronary artery calcium score actually measures, why it’s really just the tip of the iceberg, and why a higher repeat score does not necessarily mean your treatment failed... | 10m 21s | ||||||
| 4/13/26 | Is Your Candle Slowly Poisoning You? Vascular Surgeon Reacts to Joe Rogan | Joe Rogan got half a million people talking about what's happening inside their blood vessels. As a vascular surgeon, I've spent my career trying to do exactly that. So when a celebrity does it for me, I pay attention (and thank my lucky stars ;). In the clip, Dr. Shauna Swan joins Joe Rogan to discuss the surprising hazards linked to everyday household products. In my reaction, I go through the actual studies behind the microplastics- and forever chemicals-cardiovascular disease conversatio... | 9m 12s | ||||||
| 3/30/26 | GLP-1 Drugs Cut Heart Attack Risk — And It Has Nothing to Do With Weight | SELECT trial explained: does semaglutide reduce cardiovascular risk because of weight loss, or is something else going on? In this video, I break down the SELECT trial and the follow-up analysis examining whether the cardiovascular benefit of semaglutide was directly mediated by weight loss. The answer matters, because the data suggest the reduction in major adverse cardiovascular events was not simply a function of people losing more weight. I’m a board-certified vascular surgeon focused on... | 26m 55s | ||||||
| 3/23/26 | What We Get Wrong About Poor Circulation (with Vascular Surgeon Dr. Jackie Majors) | When people hear “poor circulation,” they often assume the answer is a procedure. Not so fast. In this episode of Knife Down, Dr. Jacqueline Majors and I talk about when opening a blocked artery helps, when it backfires, and why the real work of saving legs often starts long before the operating room. We get into what patients with poor circulation, blocked leg arteries, leg pain with walking, smoking-related vascular disease, and diabetes actually need to know. We talk about when a procedur... | 1h 20m 53s | ||||||
| 3/8/26 | They Don’t Want You Well. They Want You Worried. | Are supplements safe? Not automatically. In this video, I explain why supplements are really drugs, why the industry has so little oversight, which products worry me most, and how I think about using supplements more safely in real life. I’m a board-certified vascular surgeon specializing in cardiometabolic prevention, and I do use supplements in practice — but in a targeted, evidence-informed way. Here I walk through the biggest myths about supplements, the real risks people ignore, the cat... | 23m 17s | ||||||
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| 3/2/26 | When "Healthy" Is a Lie: @DrFordBrewer on Insulin Resistance, Hidden Plaque & His Prevention Pivot | • Feeling “healthy” is not a screening test. In this episode, Dr. Ford Brewer ( @DrFordBrewer ) tells the origin story: an ER doc who believed he was doing the right things—until he actually checked and found plaque. That discovery didn’t just change his health plan. It changed his entire job. He walked away from the adrenaline economy of emergency medicine and moved into cardiovascular prevention and teaching, because patching crises is not the same as stopping them. We talk a... | 1h 04m 13s | ||||||
| 3/2/26 | The Blood Pressure Myth That Won't Die: A Vascular Surgeon Reacts to @DrAlexWibberley | Hypertension isn’t a mystery. It’s physics. And it’s quietly remodeling your arteries while you’re out here arguing with your salt shaker. In this reaction to @DrAlexWibberly, I’m mostly nodding along—because he nails the big idea: blood pressure is a mechanical force + a hormonal system problem, not just “too much sodium.” We talk through the three levers that create blood pressure (cardiac output, blood volume, vascular resistance) and why the “salt is the villain” storyline is incomplete ... | 28m 31s | ||||||
| 3/2/26 | HIIT vs Heart Plaque: Randomized Trial Deep Dive | In this research report deep dive, I walk through a randomized trial that asked a very specific, very modern question: can high-intensity interval training (HIIT) measurably change coronary atherosclerotic plaque—not just your VO₂ max? We go line-by-line through the paper: who they enrolled, what the HIIT protocol actually was, how they measured plaque (and plaque type), what outcomes moved, what didn’t, and the limitations that matter before you turn “exercise is medicine” into a personalit... | 42m 27s | ||||||
| 3/2/26 | My CIMT Walkthrough: How I Spot Plaque in 30 Minutes or Less | Sign up for more information on my own practice here: https://corsighthealth.com/ Wondering what a CIMT (carotid intima-media thickness) exam is actually like? In this quick “what to expect” walkthrough, I show you how the test works, what it feels like, how long it takes, and what the images can tell us about early plaque and cardiovascular risk. Other tools for optimal health (note these are affiliate links): Home BP Cuff: https://amzn.to/49Cq7rh Sonicare Toothbrush: https://amzn.to/3Kllf... | 6m 41s | ||||||
| 3/2/26 | ChatGPT’s Medical Reply - Vascular Surgeon Fact Check! | A subscriber asked about statins—so I made ChatGPT answer first… and then I fact-checked it as a vascular surgeon. We’re talking cholesterol, LDL, ApoB, plaque growth and plaque rupture, and what “prevention” actually means when the goal is avoiding the first heart attack (or the next one). We’ll cover when statins make sense, when they’re oversold, and why “my numbers are fine” doesn’t always mean your arteries are fine. This is AI in healthcare with a reality check. For my more complete ph... | 18m 28s | ||||||
| 3/2/26 | New Drugs Cut Lp(a) Over 90%...Will They Prevent Heart Attacks? | In this video, we explore the exciting pipeline of drugs targeting lipoprotein a and its implications for cardiovascular disease prevention. We'll examine how these cholesterol drugs are designed to work, including those utilizing sirna technology, and discuss the reasons for both enthusiasm and caution regarding this medical breakthrough. This discussion aims to clarify the current landscape of new treatments and what questions still need answers. Here’s what I cover: - The strategy for lo... | 24m 50s | ||||||
| 3/2/26 | The Cholesterol Myth That Won’t Die – A Vascular Surgeon Reacts to @Physionic | Original video: https://www.youtube.com/watch?v=mJLKTyKy-14&list=WL&index=31 We’ve been obsessed with this cholesterol number for decades — but what if we’ve been chasing the wrong thing this whole time? In this video, I’m reacting to Physionic’s powerful “We Were Wrong” episode on cholesterol, where he argues that one widely celebrated marker has never actually been shown to be a therapeutic target in major trials. We break down: • Why we’ve overvalued this marker, despite nev... | 15m 41s | ||||||
| 3/2/26 | High Lp(a)? Here's What Works (And What Doesn't) | High Lp(a) cholesterol is common—and frustrating—because there’s no single drug that fixes it (yet). In this video, I walk through how I manage elevated lipoprotein(a) today, using the tools we actually have: metabolic health optimization, LDL/ApoB lowering, statins, PCSK9 inhibitors, aspirin (in select patients), and menopausal hormone therapy where appropriate. If you’ve been told your Lp(a) is high and then… nothing else, this video is about what does matter right now—and what doesn’t. T... | 16m 56s | ||||||
| 3/2/26 | A Meal to Unclog Arteries? Watch This First (Dr. J Reacts to @LeonidKimMD ) | In this video, I react to a recent post from Dr @LeonidKimMD a physician who shares evidence-based nutrition and lifestyle medicine content here on YouTube. His channel focuses on strategies for health, and this video discusses a meal pattern proposed to support cardiovascular health. In this reaction, I walk through: • What claims like “unclogging arteries” usually mean in physiologic terms • Where diet and lifestyle can meaningfully improve vascular health • Where expectati... | 29m 25s | ||||||
| 3/2/26 | 1 in 5 People Have This — And Most Never Get Tested | Lp(a) Explained: The Genetic Cholesterol Most Doctors Don’t Check (And Why It Matters) You can be fit, lift heavy, eat “clean,” and still have a hidden cardiovascular risk most standard cholesterol tests miss. In this video, I break down lipoprotein(a), or Lp(a) — a genetically determined cholesterol particle that quietly raises the risk of heart attack, stroke, peripheral artery disease, and calcific aortic valve stenosis, even in people who look metabolically healthy. You’ll learn:  ... | 10m 13s | ||||||
| 3/2/26 | My First No Incision Bypass | Advanced Treatment for Arterial Blockages | Is it possible to fix a blocked artery without major open surgery? In this video, I explain the Detour procedure (Percutaneous Transmural Arterial Bypass)—a new, minimally invasive technique that routes blood flow around blockages to restore circulation. For patients with advanced peripheral artery disease (PAD), this innovation offers a powerful alternative to traditional leg bypass surgery. DETOUR2 trial results: https://www.jvascsurg.org/article/S0741-5214(24)00307-0/fulltext Sign up for... | 6m 47s | ||||||
| 3/2/26 | 5 Things I've Learned On Call as a Surgeon | What Is It Really Like Being On Call as a Surgeon? | Life, Death, Burnout & Decisions at 2AM What does being on call as a surgeon actually mean—beyond the pager, the scrubs, and the stereotypes? In this video, a board-certified vascular surgeon pulls back the curtain on life on call: the anxiety, the ethical decisions made at 2 a.m., the mistakes you never forget, and the rules that keep patients safe when you’re exhausted and human. This isn’t a highlight reel. It’s an honest look at ... | 25m 14s | ||||||
| 3/2/26 | Are We Treating Cholesterol Completely Wrong? | Vascular Surgeon Explains | Cholesterol isn’t the villain you were taught to fear — it’s the fuel. And in this video, I’m breaking down why fuel isn’t the same thing as fire, and why most people are fighting the wrong battle when it comes to heart disease. If you’ve ever stared at your LDL number and wondered, “Is this actually going to kill me?” — this one’s for you. Most people obsess over cutting down a few trees… while ignoring the raging sparks flying everywhere. In this episode, we cover: ✔️ Why LDL/ApoB matter... | 20m 39s | ||||||
| 3/2/26 | Hormones, Hot Flashes, & Heart Disease: Your Doctor Didn't Tell You THIS | Dr. Lily Johnston is back to discuss why women are often underdiagnosed and undertreated for heart disease, highlighting often-overlooked risks in standard assessments. She addresses common menopause myths surrounding menopausal hormone therapy (HRT) and its impact on cardiovascular health. This discussion seeks to inform and reassure viewers about the latest research and recommendations for women's health and heart health, including a thorough cardiovascular risk assessment. ⸻ Find a menop... | 19m 58s | ||||||
| 3/1/26 | 3 Myths About Menopause & Heart Health — A Surgeon Explains | Most women have been taught to fear menopausal hormone therapy. Blood clots. Heart attacks. Strokes. A generation of headlines convinced millions that estrogen was dangerous—even when the science didn’t actually say that. As a vascular surgeon and metabolic health specialist, I spend my days treating the consequences of cardiovascular disease. And I can tell you this: women deserve far better information than they’ve been given. I break down the three biggest myths about menopausal hormone ... | 19m 58s | ||||||
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