#32 “Medical malpractice”: Matt Kaeberlein on biological age tests

#32 “Medical malpractice”: Matt Kaeberlein on biological age tests

From LEVITY by Peter Ottsjö

September 23, 2025 · 1h 50m · Episode 32

About this episode

Matt Kaeberlein discusses biological age tests and the implications of their misuse in the context of aging science.

One idea I’ve had lately is to put together a list of people to trust in geroscience and the longevity field more broadly. (And I might do it - keep an eye on reachlevity.com - and subscribe while you’re at it!) Matt Kaeberlein would not only make that list - he’d likely be right at the top. He’s rigorous, precise in his wording, and always puts integrity ahead of hype. But, and this is important, I wouldn’t characterize him as a skeptic. He’s a realist who insists on evidence, yet at the same time he’s visionary and deeply optimistic about what aging science can deliver. Matt is probably best known for his pioneering work on rapamycin and for co-founding the Dog Aging Project. In this episode, though, we also talk about Optispan - his proactive healthcare company - and Ora Biomedical, where the WormBot platform is screening thousands of interventions for effects on lifespan. We get into therapeutic plasma exchange (TPE), how artificial intelligence might accelerate discovery, and even his favorite science fiction books. And true to form, Matt doesn’t hold back. He calls out irresponsible use of biological age tests - going so far as to label it “medical malpractice” - and…

People in this episode

Host: Peter Ottsjö

Guest: Matt Kaeberlein

Topics covered

  • geroscience
  • longevity
  • biological age tests
  • healthcare
  • artificial intelligence
  • medical malpractice

Keywords

  • geroscience
  • longevity
  • biological age tests
  • medical malpractice
  • artificial intelligence
  • healthcare

Mentioned in this episode

Organizations: Dog Aging Project, Optispan, Ora Biomedical, NIH

Products: WormBot, therapeutic plasma exchange (TPE)

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