
Insights from recent episode analysis
Audience Interest
Podcast Focus
Publishing Consistency
Platform Reach
Insights are generated by CastFox AI using publicly available data, episode content, and proprietary models.
Total monthly reach
Estimated from 3 chart positions in 3 markets.
By chart position
- 🇨🇦CA · Technology#1355K to 30K
- 🇺🇸US · Technology#1815K to 30K
- 🇬🇧GB · Technology#1985K to 30K
- Per-Episode Audience
Est. listeners per new episode within ~30 days
4.5K to 27K🎙 Daily cadence·57 episodes·Last published yesterday - Monthly Reach
Unique listeners across all episodes (30 days)
15K to 90K🇨🇦33%🇺🇸33%🇬🇧33% - Active Followers
Loyal subscribers who consistently listen
6K to 36K
Market Insights
Platform Distribution
Reach across major podcast platforms, updated hourly
Total Followers
—
Total Plays
—
Total Reviews
—
* Data sourced directly from platform APIs and aggregated hourly across all major podcast directories.
On the show
Recent episodes
Joanna Strober, Midi Health CEO, on the menopause Tupperware parties that built a unicorn
Jun 23, 2026
46m 54s
Ric Sinclair, CEO of Cotiviti on why payer-provider friction is finally fixable
Jun 16, 2026
1h 02m 19s
Dr. David Carmouche, Lumeris: Why AI is primary care's best chance at survival
Jun 9, 2026
48m 49s
How SaaS is evolving from software to AI solutions | Artera's Guillaume de Zwirek & Dan Goldsmith
Jun 2, 2026
53m 16s
Chris Altchek, Cadence CEO, on earning the right to deploy clinical AI
May 26, 2026
49m 42s
Social Links & Contact
Official channels & resources
Official Website
Login
RSS Feed
Login
| Date | Episode | Description | Length | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 6/23/26 | ![]() Joanna Strober, Midi Health CEO, on the menopause Tupperware parties that built a unicorn | Joanna Strober, CEO of Midi Health, joins Chrissy Farr to talk about building one of the first scaled companies in women's midlife health, and why the category didn't produce a unicorn until this year despite an obvious market need. They cover Midi's "B2B for show, B2C for dough" strategy, how a 150-patient pilot turned a hormone-access company into a full primary care business, and what changed when Joanna posted a public apology to patients on LinkedIn after a patch shortage overwhelmed the company's support team.—SPONSOR: Baker Health🩺 This episode is brought to you by Baker Health. Evidence-based medicine and real holistic care, under one roof, with labs, results, and 24/7 live doctor chat all in one app.Download the Baker Health App: https://linktr.ee/baker_health Learn More: https://www.bakerhealth.com/ The only practice in NY & NJ where you can text your doctor directly and get same-day reservations.Make a Reservation: https://reservations.bakerhealth.com/medical?utm_source=lifers —LINKS: Midi Health: https://www.joinmidi.com/Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Joanna:https://www.linkedin.com/in/joannastrober https://x.com/joannastrober Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:38) Intro(02:14) Joanna's founder journey(04:27) Lessons from Kurbo(06:23) Why women's health is hard(08:12) Midi's D2C brand bet(12:30) What Midi actually treats(14:36) Labs and diagnostics(15:51) Sponsor: Baker Health(17:06) GLP-1s and midlife weight(20:55) Funding and timing tailwinds(24:10) Founder advice: think bigger(26:43) AI to scale empathy(31:29) LinkedIn and trust building(35:42) Destigmatizing menopause(40:12) Organic marketing playbook(42:41) Expansion, AI, and research(45:22) Wrap | 46m 54s | ||||||
| 6/16/26 | ![]() Ric Sinclair, CEO of Cotiviti on why payer-provider friction is finally fixable | In this episode of Lifers, Christina Farr sits down with Ric Sinclair, CEO of Cotiviti, to tackle one of healthcare's most stubborn paradoxes: why does a $5 trillion system keep expanding its own problem set? Ric makes the case that healthcare doesn't have a data problem or a technology problem, it has a coordination problem, and that Cotiviti is building the end-to-end infrastructure layer the industry has never had. They discuss why payers and providers aren't really villains, how AI is poised to make things worse before it makes them better, and what it would take to finally make healthcare fairer and more transparent for everyone.—Thanks to our sponsor Cotiviti. Cotiviti’s infrastructure platform enables healthcare organizations to deliver better care at lower cost through advanced technology and data analytics that improve the quality and sustainability of healthcare in the United States. Cotiviti’s solutions increase transparency and collaboration between payers and providers while empowering them to reduce medical and administrative costs, enable better health, improve claims payment efficiency, streamline operations, drive interoperability, and advance value-based care. Its customers serve the majority of U.S. healthcare consumers, providing coverage and care for over 300 million members and patients. For more information, visit https://www.cotiviti.com/ —LINKS:Cotiviti: https://www.cotiviti.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Ric:https://www.linkedin.com/in/ricsinclair Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:32) Intro(01:17) Drumming to leadership(04:18) From music to health tech(06:23) Why healthcare feels broken(08:52) Waystar product lessons(11:18) Coordination not data(12:47) AI could raise costs(16:06) Building Cotiviti vision(18:22) The dark side debate(26:48) Trust gaps and mediation(27:59) Execution over ideas(30:34) Teasing the next idea(30:51) Gold carding debate(32:12) Coordination over programs(34:00) Planting the orchard(35:15) AI business models(37:39) Humans in the loop(40:56) Reskilling and job shifts(43:14) AI literacy mindset(46:20) Polite to the bots(47:51) Teams and productivity(51:09) Creativity still human(55:34) Company values framework(57:37) Legacy and waste reduction(01:01:16) Wrap | 1h 02m 19s | ||||||
| 6/9/26 | ![]() Dr. David Carmouche, Lumeris: Why AI is primary care's best chance at survival | In this episode of Lifers, Christina Farr sits down with Dr. David Carmouche, Chief Medical and Chief Commercial Officer at Lumeris and newly appointed advisor to HHS and CMS, to explore one of healthcare's most urgent questions: can primary care be saved, and is AI the thing that finally does it? They discuss how decades of administrative burden, misaligned payment models, and the erosion of the longitudinal doctor-patient relationship turned primary care into an impossible job, and why AI represents the first real opportunity to reimagine it. They also explore the audacious vision of a single PCP managing 5,000 to 10,000 patients through autonomous AI, why the office visit needs to become the exception rather than the starting point, and what it will take to rebuild a system that actually works for patients and clinicians alike. —Lumeris is a physician-first healthcare transformation company advancing the future of primary care through Tom, its AI-powered Primary Care as a Service platform designed to function as a proactive member of the care team embedded directly in clinical workflows. Tom autonomously supports best next actions that help providers expand capacity, improve patient access, and reduce administrative burden while enabling more personalized, scalable care delivery. —LINKS:Lumeris: https://www.lumeris.com/ Bob Wachter episode: https://www.youtube.com/watch?v=p6U1fX1JgVk Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:David:https://x.com/carmouchemd Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:45) Intro (01:27) Is primary care back?(03:13) Why primary care declined(07:03) Consumer convenience wins(08:20) Payment model problem(11:24) New payment experiments(15:25) AI sandboxes and scope(17:14) Physicians friend or foe(22:07) Limits safety and rigor(24:11) Privacy vs insight tradeoff(28:16) AI finds longitudinal patterns(30:05) Scaling panels to 5000(35:29) Wearables data control panel(40:18) Bridging consumer and EHR(43:34) Why you need a PCP(46:44) Longevity as primary care 2.0(47:46) Wrap | 48m 49s | ||||||
| 6/2/26 | ![]() How SaaS is evolving from software to AI solutions | Artera's Guillaume de Zwirek & Dan Goldsmith | In this special episode of Lifers, Christina Farr sits down with Guillaume de Zwirek, CEO of Artera, and Dan Goldsmith, Co-founder & Partner at Proofpoint Capital, and Board Member at Artera, with 30 years of C-Level and Founder operating experience. They tackle one of the most fundamental questions in healthcare tech right now: what actually is AI, and how should companies operationalize it? They discuss why AI is neither traditional SaaS nor consulting services but something entirely new: bespoke solutions delivered at the speed and cost of software, and why the companies that fail to grasp this distinction are already quietly dying. —Artera is the leading agentic healthcare company offering AI solutions for patient communications, strengthening how providers connect with and care for their patients.—LINKS:Artera: https://artera.io/ Proofpoint Capital: https://www.proofpointcapital.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Gui:https://www.linkedin.com/in/guidezwirek Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead in(00:42) Intro(01:43) What is AI today(03:55) Valuing AI businesses(07:46) Durability and moats(10:02) AI-first operating model(12:25) Builders and reorg(14:43) Investor and customer diligence(17:24) Healthcare stakes trust(20:17) From implementation to instant(24:49) Who thrives in AI era(26:29) AI-native work habits(26:52) Org memory at scale(27:55) Personal bots from data(29:19) Solutions not software(31:06) Healthcare barriers to AI(33:06) Making workflow personal(34:24) Agentic customization fast(36:55) Self-improving agent harness(39:42) EHR future and data(44:42) Human connection wins(47:02) Winners and losers(50:22) Leadership and conviction(52:00) Wrap | 53m 16s | ||||||
| 5/26/26 | ![]() Chris Altchek, Cadence CEO, on earning the right to deploy clinical AI | This week on Lifers, Christina Farr sits down with Chris Altchek, who went from investment banking to building Mic, a digital media company that reached 100 million readers, before co-founding Cadence, a health tech company now managing nearly 100,000 chronic disease patients per day. They dig into the hard lessons from media's platform-dependency collapse, what it really takes to build a sustainable business inside the US health system, and why Chris believes AI could make elite-level care accessible to far more Americans within a decade. Dive into the Granola notes from this episode: https://notes.granola.ai/t/02b3e52a-40ef-45e7-bc18-ac35b335e044-009c2hma —Join Christina for an upcoming webinar:* 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com—LINKS:Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Chris:https://www.linkedin.com/in/chrisaltchek https://x.com/caltchek Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:58) Intro(02:57) Early life and trading(05:22) Investor mindset lessons(09:22) Perseverance as founder(14:35) Mic Media lessons(18:53) Sponsor break(19:46) Cadence origin story(23:33) Business model and reimbursement(28:30) Data and remote monitoring(30:46) Winning health systems trust(35:16) CMS Access model strategy(39:25) Cutting inefficiency in care(42:31) Clinical AI that matters(45:27) Future of US healthcare(48:35) Wrap | 49m 42s | ||||||
| 5/19/26 | ![]() Why price transparency took a decade to crack | Heather Fernandez, Solv | In this episode of Lifers, Christina Farr sits down with Heather Fernandez, CEO of Solv and former Trulia executive, to dig into the question that has stumped healthcare for decades: why don't patients know what their doctor visit will cost? They discuss how Solv evolved from a marketplace for urgent care appointments into an AI-first operating system for on-demand healthcare,built on over 100 million real patient visits, and why AI is finally cracking the price transparency problem after more than a decade of trying. They also explore what it really means to "skip the landline" and rebuild workflows from scratch, how Solv's voice agent Maya is handling millions of after-hours calls no front desk team could staff, and more.—Thanks to Solv who facilitated this conversation. Solv is the AI-first operating system for on-demand healthcare, helping providers automate everything from patient access to insurance verification and payments.—LINKS: Solv: https://www.solvhealth.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Heather:https://www.linkedin.com/in/heatherfernandez https://x.com/heathermirj Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:58) Intro(02:24) Leveraging walking meetings to foster authentic collaboration (04:47) Heather's career from Capitol Hill to venture-backed PR(07:29) Deciding to join a room of misfits at Trulia (09:27) Managing family milestones alongside major tech exits (11:33) From real estate to a complex healthcare market (16:05) Projecting an Uber-like paradigm shift for medical pricing (19:23) Bottoms-up data ingestion to solve localized plan complexity (22:15) Transitioning Solv from consumer marketplace to AI-first OS (23:47) Mapping structural forces driving a sudden consumer health pull (25:21) Deploying automated voice agents to eliminate front-desk administrative drag (27:13) Forcing organizational transformation amidst high-profile tech layoffs (33:31) Applying a "skip the landline" mantra to legacy workflows (37:27) Navigating the three operational phases of AI adaptation (39:43) Reshaping the healthcare front door through tech investments(42:58) Challenging industry insiders who dismiss medical cost urgency (43:48) Calling for passionate tech outsiders to disrupt entrenched structures(45:37) Wrap | 46m 37s | ||||||
| 5/12/26 | ![]() Behind Kalshi’s $22B rise: Betting on addiction with Dr. Rian Kabir | In this special episode of Lifers, Christina Farr sits down with Dr. Rian Kabir, a psychiatrist and medical AI expert, to discuss the mental health implications of Kalshi's $22 billion valuation. They explore whether prediction markets constitute gambling, the addictive risks of frictionless betting apps, and what Rian is seeing in his own clinical practice. A timely conversation on the societal costs of a rapidly growing industry.—Join Christina for an upcoming webinar:* 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com—LINKS: Chrissy’s Tweet: https://x.com/chrissyfarr/status/2053457349075976665?s=20 Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Rian:https://x.com/RianKMD Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Intro(00:24) Kalshi valuation sparks debate(02:04) Why app gambling hits hard(04:55) Addiction risk factors explained(06:26) Kalshi vs sports betting apps(08:18) Clinical fallout and suicide risk(10:05) Sponsor: Granola(10:44) Age limits and young brains(13:02) Juul parallels and VC ethics(15:17) Regulation incentives and society(17:17) Wrap | 19m 10s | ||||||
| 5/5/26 | ![]() Building Maven Clinic when no one believed with CEO Kate Ryder | In this episode of Lifers, Maven Clinic founder and CEO Kate Ryder joins host Christina Farr to discuss her journey building the first unicorn in the women's health category. Kate reflects on the "wartime" mentality of the early years, the challenges of scaling to a $500 million company, and the resilience needed to face investors who initially dismissed the space as a "niche" market. They explore the industry’s evolution, from overcoming Silicon Valley “trolls” to leading the transition of digital health from niche point solutions into massive, integrated platforms. Dive into the Granola notes from this episode: https://notes.granola.ai/t/d2c2adc9-b014-415e-91ab-75716d5784fd-008umkv4 —Join Christina for an upcoming webinar:* 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3—SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com —LINKS: Maven Clinic: https://www.mavenclinic.com/ Sachin Jain on Lifers: https://www.youtube.com/watch?v=Tvtakm7NMnI Sean Duffy and Stephanie Davis on Lifers: https://www.youtube.com/watch?v=sLRmtmcQjP4 Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Kate:https://www.linkedin.com/in/kate-ryder-87474933/ https://x.com/_KateRyder Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Lead In(00:58) Intro(02:09) Founder energy and motivation(02:41) Which growth stage hurts(06:42) Hiring for the stage(10:19) Storytelling as a superpower(17:12) Sponsor: Granola(18:05) Selling change without fear(21:16) ROI and aligned incentives(23:57) What carve outs mean(26:33) Point solutions to platforms(29:23) Women VCs and fundraising bias(36:17) How personal to get(38:47) Consumer health comes back(42:09) Gen Z parenthood and misinformation(47:12) Wrap | 49m 53s | ||||||
| 4/28/26 | ![]() Dr. Oliver Kharraz on the decades-long journey to make scheduling a doctor's appointment easier | This week on Lifers, Christina Farr interviews Dr. Oliver Kharraz, the CEO of Zocdoc. They discuss the complexities of navigating the healthcare industry and the "culture shock" of modernizing medical scheduling. They explore Zocdoc’s evolution from a startup to a major platform, highlighting strategic shifts in their business model and the challenge of balancing growth with regulatory demands. They also discuss the future, examining how Voice AI and LLMs are poised to transform the "front office" and improve patient access to care. Dive into the Granola notes from this episode: https://notes.granola.ai/t/a4284c84-160f-4a64-8761-dfd8d8680064-008umkv4 —Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3—SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com—LINKS: Zocdoc: https://www.zocdoc.com/ The 2028 Global Intelligence Crisis - Citrini Research: https://www.citriniresearch.com/p/2028gicChrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books—FOLLOW:Oliver: https://www.linkedin.com/in/kharraz/ https://x.com/oliver_kharraz Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(00:57) Intro(03:08) Healthcare culture shock(05:32) Zocdoc origin story(06:04) Hidden inventory insight(07:13) Early tech reality check(07:33) The Post-it note problem(09:03) New York first strategy(10:51) Why healthcare is harder(12:32) Startup mindset and IPO(15:22) Sponsor: Granola(16:01) Business model overhaul(19:06) Backlash and whale dinners(22:04) Regulatory green light(23:27) Lessons on transparency(25:09) Fair share friction(26:21) Transition pays off(27:43) Growth versus profit(29:18) Shopify for access(30:47) Voice AI front desk(34:27) Competing with startups(37:02) LLMs need transactions(42:16) Reserve capacity reality(44:41) Autonomous care limits(46:24) Optimism on AI jobs(50:22) Wrap | 51m 51s | ||||||
| 4/21/26 | ![]() Dr. Farzad Mostashari, Aledade CEO, on why more doctors are going independent | This week on Lifers, Christina Farr is joined by Farzad Mostashari, CEO of Aledade and former National Coordinator for Health IT, alongside co-host Mike Desjadon, CEO of Anomaly Health. Farzad traces his journey from CDC to spearheading the nationwide rollout of electronic health records. They discuss why value-based care is the only viable path forward, how AI is finally making it possible to deliver population health insights at scale, and what the current administration is getting right (and wrong) on payment reform. Dive into the Granola notes from this episode: https://notes.granola.ai/t/5a6d9ee2-8592-4471-adec-2d66797d86fd-008umkv4— Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERS Interested in sponsoring the show? lifers@a16zstudios.com—LINKS: Syndromic surveillance piece: https://www.cnbc.com/2020/04/04/syndromic-surveillance-useful-to-track-pandemics-like-covid-19.html On the ACCESS MODEL: https://secondopinion.media/p/cms-unveils-major-new-outcomes-based-model-for-tech-enabled-care-what-digital-health-leaders-need-to Aledade: https://aledade.com/ Anomaly: https://www.findanomaly.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Farzad:https://www.linkedin.com/in/farzad-mostashari-933210 Mike:https://www.linkedin.com/in/mike-desjadon-4a0a21a/ https://x.com/Mike_Desjadon Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Intro(03:01) Disease hunter origins(04:50) Saving lives at scale(06:54) EHRs and incentives(09:22) Advice for AI builders(10:46) Payment reform bright spots(14:26) Sponsor: Granola(15:20) Deflation and CPT shakeup(17:47) Paying for outcomes(20:26) Aledade and ACCESS model(24:23) AI needs value models(25:58) Electronic health records copilot breakthrough(28:15) Rural care opportunity(30:26) Accountability drives adoption(32:58) Concierge care tradeoffs(34:43) Scaling primary care capacity(35:53) Doctors as entrepreneurs(38:13) Mission and policy moves(41:02) Rapid fire predictions(43:51) Bipartisan VBC | 45m 38s | ||||||
Want analysis for the episodes below?Free for Pro Submit a request, we'll have your selected episodes analyzed within an hour. Free, at no cost to you, for Pro users. | |||||||||
| 4/18/26 | ![]() [Emergency Pod] Peptides - Part 2 with Dr. Jonathan Slotkin of Scrub Capital | In this special episode of Lifers, Christina Farr sits down with Dr. Jonathan Slotkin (neurosurgeon, CMO, and co-founder of Scrub Capital) for a timely conversation on peptides and what the latest HHS announcements mean for patients and the longevity industry. Jon breaks down his own protocol, makes the case that the longevity conversation has too often left women out, and closes with a watch-out for investors: the potential descheduling of testosterone. —SPONSOR: Granola Granola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERS Interested in sponsoring the show? lifers@a16zstudios.com —LINKS: Scrub Capital: https://scrubcapital.com/ Ashley Winter on Twitter: https://x.com/AshleyGWinter Peptide Reclassification: https://peptide-db.com/guides/fda-peptide-reclassification-2026 Testosterone/TRT expansion: https://www.fda.gov/news-events/press-announcements/fda-takes-step-forward-testosterone-therapy-men Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Jon:https://www.linkedin.com/in/slotkinjr https://x.com/slotkinjr Christina Farr:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Intro(01:08) What are peptides(02:25) Safety and FDA nuance(04:53) Clinician survey tribes(07:15) Jon’s personal protocol(10:03) Women and hormone gaps(14:08) Sponsor: Granola(14:47) Why peptides are everywhere(17:11) Finding the right provider(20:47) Follow John and final nugget(21:49) Testosterone descheduling watch(22:31) Wrap | 23m 31s | ||||||
| 4/17/26 | ![]() [Emergency Pod] Peptides - Part 1 with Sunita Mohanty of Ultralight | Christina Farr sits down with Sunita Mohanty, CEO and Co-founder of Ultralight, an AI-native operating system powering over 75 functional and longevity medicine clinics across the U.S. Sunita breaks down the regulatory whiplash driving a peptide black market, why the evidence base still hasn't caught up with patient demand, and why individual response varies so dramatically. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: Granola Granola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/liferswith code: LIFERS Interested in sponsoring the show? lifers@a16zstudios.com —LINKS: Ultralight: https://www.ultralighthealth.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Sunita: https://www.linkedin.com/in/sunita-mohanty/ https://x.com/sunitasmohanty Christina Farr:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Welcome to Lifers(00:22) Peptides everywhere(01:00) Meet Sunita Mohanty(01:58) Astrology to stacks(02:54) Gray areas and risks(05:16) Clinicians and compounding(06:36) Sponsor break Granola(07:15) Doctors self experimenting(08:35) Why peptides skew male(10:11) Prevention and policy(11:35) Wrap up and next steps | 12m 46s | ||||||
| 4/13/26 | ![]() The case for a virtual-first healthcare system with Dr. Chris Gallagher, Founder and Chief Strategy Officer and Dr. Blake Porter, Chief of Maternal-Fetal Medicine at Access TeleCare | In this episode of Lifers, Christina Farr sits down with Dr. Chris Gallagher (founder and Chief Strategy Officer of Access TeleCare) and Dr. Blake Porter (Chief of Maternal Fetal Medicine at Access TeleCare) to explore the state and future of virtual subspecialty care. The conversation centers on a second wave of telehealth growth, moving beyond the pandemic-era boom into harder-to-reach territory like high-risk pregnancy care, rural ICUs, and other subspecialties where trained clinicians are hard to find and can't simply be manufactured at scale. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —Thanks to our sponsor Access TeleCare, the largest provider of acute specialty telemedicine, serving hospitals and health systems across the U.S.—LINKS: Access TeleCare: https://accesstelecare.com/ Second Opinion’s interview with Chris Clomp: https://secondopinion.media/p/the-big-interview-we-sit-down-with-rfk-jr-s-no-2-chris-klomp Charted: Where Inflation Has Hit the Hardest (2000–2025): https://www.visualcapitalist.com/chart-inflation-hit-the-hardest-by-category-2000-2025/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Chris:https://www.linkedin.com/in/chrisgallaghermd/ Blake: https://www.linkedin.com/in/blake-porter-62b51367 Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS: (00:00) Preview(01:02) Intro(03:18) Telehealth growth and market reset(06:08) Virtual specialty care in women's health(08:41) Solving the subspecialist shortage(12:01) What virtual care really means(14:51) Care at home and remote monitoring(17:55) Rural Health Fund and Medicaid cuts(21:39) Reducing hospital transfers with telemedicine(23:49) Change management in healthcare(25:08) Trusting clinical change(26:32) Doctors in business roles(27:36) No margin no mission(31:02) Defining quality and sustainability(32:55) Making healthcare deflationary(38:39) Rural innovation ground zero(42:10) Picking the right vendors(44:25) Founding a virtual ICU(48:15) Selling into health systems(50:50) Wrap | 52m 04s | ||||||
| 4/3/26 | ![]() Anyone can build a clinic now. Should they? | Josh Tauber and Keaton Bedell | On this special mini episode of Lifers, Christina Farr speaks with Josh Tauber, multi-time COO and founder, and Keaton Bedell, co-founder and CEO of Bridge, about a recent New York Times article on Medvi, a cash-pay GLP-1 company valued at $1.8 billion. The conversation covers the infrastructure shifts enabling virtual care companies to launch faster than ever, the legal and regulatory questions still unresolved, and what separates sustainable virtual care businesses from those chasing a short-term opportunity.— Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com—LINKS: NY Times article: https://www.nytimes.com/2026/04/02/technology/ai-billion-dollar-company-medvi.html Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW: Keaton:https://www.linkedin.com/in/keatonbedell/ https://x.com/keatonbedell Josh:https://www.linkedin.com/in/joshuatauber/ Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Intro(01:51) Leveraging turnkey infrastructure to spin up virtual clinics(02:52) Evaluating the lack of traditional software moats in health tech(04:58) Analyzing the legality and ethics of cash-pay medical groups(06:37) Sponsor: Granola(07:16) Analyzing the legality and ethics of cash-pay medical groups(08:02) Improving patient access and agency through direct-to-consumer models(09:50) Building competitive advantages through patient trust and retention(11:40) Bootstrapping virtual care companies without traditional venture capital(13:08) Wrap | 14m 18s | ||||||
| 3/30/26 | ![]() How revenue cycle is evolving from "battle of the bots" to the smash hit application for AI with Terri Meier | For this week's episode of Lifers, Chrissy recorded live with Terri Meier, Assistant Vice Chancellor for Revenue Cycle at UAMS, at the HFMA Revenue Cycle Conference in Dallas. Together they pull back the curtain on the $300 billion part of healthcare nobody wants to talk about. Dive into the Granola notes from this episode: https://notes.granola.ai/t/b25d9642-3266-4bd0-bfb8-d119f7c7f8c0-008umkv4 — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —Thanks to our sponsor Smarter Technologies, a leading AI-powered revenue management platform that combines proprietary clinical agents, human-in-the-loop AI agents, clinical ontology, and global financial and administrative services. The company enables healthcare organizations to automate the entirety of their administrative and financial workflows—helping optimize operational outcomes, reduce costs, and improve patient experiences. For more information, visit www.smartertech.com—LINKS: HFMA: https://www.hfma.org/ HFMA Revenue Cycle Conference 2026: https://www.hfma.org/revenue-cycle/hfma-revenue-cycle-conference-tackles-issues-big-and-small/ Second Opinion Rev Cycle piece: https://secondopinion.media/p/why-revenue-cycle-is-the-first-smash-hit-application-for-ai Smarter Technologies: https://www.smartertech.com/ Chrissy Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr Chrissy Farr on Instagram: https://www.instagram.com/cfarr/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books —FOLLOW:Terri:https://www.linkedin.com/in/terri-meier-chfp-crcr-lssgb-07a7a8a/ Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(01:03) Intro(02:17) Terri Meier and her 43-year career(04:13) Shifting focus back to the patient financial experience(07:15) Integrating revenue cycle into C-suite strategic dialogues(08:27) Navigating the battle of the bots in claims denials(12:28) Moving from manual tasks to AI orchestration and strategy(14:57) Creating new job descriptions for the innovative biller(16:59) Evaluating vendor signals and performance-based business models(19:03) Addressing financial headwinds in rural and safety net hospitals(21:59) Transforming the registration team into proactive pre-billers(23:57) The transparency gap in payer adjudication and revenue leakage(25:27) Navigating the rise of healthcare consumerism and patient liability(28:55) Closing the collection gap and verifying actual vendor ROI(32:15) Wrap | 33m 43s | ||||||
| 3/24/26 | ![]() Is healthcare safe from the SaaS bloodbath? with Omada CEO Sean Duffy and Stephanie Davis | In this episode of Lifers, Christina Farr joins Omada Health CEO Sean Duffy and healthcare industry analyst Stephanie Davis to discuss whether digital health is a resilient "safe haven" or a casualty in the current public market software "blood bath". They explore how healthcare differs from traditional SaaS because it relies on "between-visit" provider care, physical touch, and rigorous regulatory compliance rather than just "vibe-coded" software, analyze recent M&A activity, such as UHS acquiring Talkspace, and discuss how AI might shift the industry toward a "creator" model while maintaining the essential "human-in-the-loop" for patient accountability. Dive into the Granola notes from this episode: https://notes.granola.ai/t/ed07ad4e-18c1-4f8c-a8c9-9e3a17cc68c3-008umkv4 — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com —LINKS:The 2028 Global Intelligence Crisis - Citrini Research: https://www.citriniresearch.com/p/2028gicChamath Article: https://x.com/chamath/status/2033385903520129161Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Sean:https://www.linkedin.com/in/seanpduffy/https://x.com/seanduffyStephanie:https://www.linkedin.com/in/stephjdavis/Chrissy:https://www.linkedin.com/in/christinafarr/https://x.com/chrissyfarr—TIMESTAMPS:(00:00) Preview(00:24) Intro(00:47) Analyzing the SaaS market bloodbath and healthcare's unique position(02:09) Omada Health's evolution from vendor to regulated care provider(04:21) Challenging the pandemic-era trend of valuing services like software(06:09) Evaluating end-market resilience for doctors versus white-collar workers(08:17) Shifting revenue models from seat licenses to value-based outcomes(11:12) Navigating the psychological shift from growth multiples to cash flow(13:51) Perception versus reality in a nascent and misunderstood industry(15:52) Bridging the gap between technology and healthcare venture capital(18:07) Sponsor: Granola(18:46) The Talkspace acquisition as a bellwether for incumbent interest(21:42) Managing clinical and regulatory governance in the age of AI(25:02) Using LLMs to navigate complex employer benefit ecosystems(28:35) Balancing the science of models with the art of medicine(29:44) Future-proofing careers by leveraging AI tools for creative creation(34:45) Wrap | 36m 23s | ||||||
| 3/17/26 | ![]() Why Graham Walker is ‘sounding the alarm’ for physicians | This week on Lifers, Christina Farr sits down with emergency physician and entrepreneur Graham Walker to discuss why the medical profession is reaching a breaking point. Graham "sounds the alarm" on the moral injury and administrative blockades that have stripped doctors of their authority and turned patient care into a "factory". They explore the "raw deal" of declining reimbursements, the absurdity of "Big Fax," and Graham’s mission to use transparency to keep physicians from abandoning the bedside. Dive into the Granola notes from this episode: https://notes.granola.ai/t/6b1bd0b8-79df-457e-bf9a-ba6b403d50f4-008umkv4 — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERSInterested in sponsoring the show? lifers@a16zstudios.com —LINKS: Offcall: https://www.offcall.com/MDCalc: https://www.mdcalc.com/Acquired Podcast Episode on EPIC: https://www.acquired.fm/episodes/epic-systems-mychart Chrissy Farr’s Website: https://www.chrissyfarr.com/Subscribe to the Second Opinion Newsletter: https://secondopinion.media/Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Graham:https://www.linkedin.com/in/graham-walker-md/ Chrissy:https://www.linkedin.com/in/christinafarr/https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview (00:46) Intro(02:03) Graham’s background(02:55) Driving physician leverage through salary and workload transparency(03:45) Why emergency physicians are naturally suited for entrepreneurship(06:11) Extracting a nine-year-old bullet from a patient's chest(09:45) Loss of physician authority as the root of burnout(13:53) Patient frustration with opaque pricing and high-deductible plans(15:38) Sponsor: Granola(16:30) Physician perspectives on trading pay cuts for system reform(19:00) The car insurance analogy for catastrophic healthcare coverage(22:31) Viewing healthcare as a public good versus a business(24:49) Redesigning systems to restore meaning and professional fulfillment(27:55) How Epic moved medicine from paper to factory billing(30:25) The brilliant business strategy and secret sauce of Epic(32:30) Addressing the hair-on-fire problem of geriatric patient complexity(35:54) Critiquing the technology industry's bias toward young healthy users(37:04) Empathy exercises and the mission to solve system inefficiency(38:46) Wrap | 40m 29s | ||||||
| 3/10/26 | ![]() President of Microsoft Science saw ChatGPT coming (and now he predicts how it will change healthcare) | Peter Lee | In this episode of Lifers, Christina Farr and Peter Lee, President of Microsoft Science explore the evolution of AI from its early "neural net" origins to the groundbreaking scale of GPT-4. Peter shares insider insights on Microsoft’s strategic partnership with OpenAI and how AI is transforming specialized fields into "full stack" generalist roles. They dive deep into the future of healthcare, highlighting how AI could eliminate administrative "coordination" layers while significantly increasing clinical patient flow. Dive into the Granola notes from this episode: https://notes.granola.ai/t/58d5e88a-5b17-46fa-85be-c3fde5d3e8f3-009c2hma— Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: https://granola.ai/lifers with code: LIFERS Interested in sponsoring the show? lifers@a16zstudios.com —LINKS: Lake Nona Impact Forum: https://lakenonaimpactforum.org/ Microsoft Research Podcast with Chrissy and Dave deBronkart: https://www.microsoft.com/en-us/research/podcast/the-ai-revolution-in-medicine-revisited-empowering-patients-and-healthcare-consumers-in-the-age-of-generative-ai/ Attention is All You Need (Google Research): https://arxiv.org/pdf/1706.03762 The Pause Letter: https://futureoflife.org/open-letter/pause-giant-ai-experiments/ The 2028 Global Intelligence Crisis: https://www.citriniresearch.com/p/2028gic?source=queue Lifers episode with Dr. Bob Wachter: https://www.youtube.com/watch?v=p6U1fX1JgVk Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Peter:https://www.linkedin.com/in/peterlee4/ https://x.com/peteratmsr Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(01:23) Intro(03:12) Evolution from deep neural nets to modern AI(04:47) Demystifying model weights and the shift to training(07:04) Breakthroughs in speech recognition and computer vision(09:25) The arrival of transformers and the attention mechanism(11:28) Why Microsoft invested when the research community ridiculed(13:54) Addressing the Pause Letter and the need for caution(16:44) AI as the moral equivalent of the transistor(19:27) Sponsor: Granola(20:06) How AI native teams restructure software development(22:29) Empowering everyone from junior devs to the CEO(28:01) Integrating AI into frontline clinical encounters and avatars(32:41) The hidden costs and upcoding risks of ambient scribes(35:48) Eliminating the coordination drag to improve patient throughput(47:45) Displacing administrative and payer-side adjudication roles(49:53) Predicting the decline of medical subspecialties(53:05) Distinguishing between mathematical proof and human creativity(56:50) Wrap | 58m 18s | ||||||
| 3/3/26 | ![]() Othman Laraki, Color CEO, on surviving three major pivots | In this episode, Christina Farr sits down with Othman Laraki, co-founder and CEO of Color. They discuss the "tortuous" yet rewarding journey of building a generational healthcare company. Othman shares how Color successfully navigated three major pivots—evolving from a cancer genetics startup into a national COVID-19 infrastructure provider, and finally into a comprehensive virtual cancer clinic. They explore the critical differences between tech and healthcare, the evolution of risk in venture capital, and why long-term success in the industry requires a deep commitment to solving complex clinical problems. Check out the Granola Notes from this episode here: https://notes.granola.ai/t/d1e8a189-ddb1-4c4f-b92d-3d4d509e4937-008umkv4. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR: GranolaGranola AI, The AI notepad for people in back-to-back meetings: granola.ai/lifers with code LIFERS Interested in sponsoring the show? lifers@a16zstudios.com —LINKS: Color: https://www.color.com/Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Othman:https://www.linkedin.com/in/othmanlaraki/ https://x.com/othman Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(00:58) Intro(01:21) Lessons from Figma and betting on the tortoise over the hair(02:45) Othman's transition from Google and Twitter to healthcare founder(05:07) Why simple features often become massively scalable business engines(06:52) Analyzing the shift from venture risk-taking to asset management(10:49) Playing the hard mode of healthcare for long-term impact(13:10) Why market structure dictates clock speed more than regulation(15:33) Navigating the conflicting financial incentives of health system CFOs(15:54) Sponsor: Granola(16:33) Navigating the conflicting financial incentives of health system CFOs (cont’d)(17:38) Surviving three pivots by aligning boards and team talent(20:37) Building infrastructure for the world's largest research study(23:51) Leaving money on the table to avoid ephemeral COVID traps(28:00) Launching a national virtual cancer clinic with the ACS(32:25) Focusing on the five high-spend pillars of patient identity(34:58) Closing the gap between clinical guidelines and early-stage screening(36:16) Removing friction to increase cancer screening rates by seventy percent(40:25) Mastering the diverse unit economics of different payer books(42:29) Preserving the nimbleness of private companies over going public(43:40) Wrap | 45m 50s | ||||||
| 2/24/26 | ![]() Dr. Ari Hoffman on escaping the era of pagers and eFaxes | In this episode of Lifers, Christina Farr examines the intricate intersection of clinical oversight and product strategy with Dr. Ari Hoffman, who oversees both domains at Collective Health. They discuss the only “because healthcare" realities that define the sector—from the friction of reconciling HIPAA regulations with modern mobile standards to the structural persistence of legacy technologies like the fax machine. They offer deep dives into the strategic role of Third Party Administrators (TPAs) and the "relentless optimism" required to navigate a market where complexity often serves as a regrettable moat for incumbents. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3—SPONSOR:This episode is brought to you by Arbiter. As Michelle says: "We don't need another instrument for the orchestra—we need to conduct the orchestra." Backed by one of the largest early funding rounds in health tech, Arbiter creates one real-time source of truth from fragmented healthcare systems, then routes referrals and handles prior auths so patients actually get to care. Learn more at https://www.arbiter.ai/.—LINKS: Collective Health: https://collectivehealth.com/ Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Ari:https://www.linkedin.com/in/ari-hoffman-2b32b87/ Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(01:02) Intro(01:56) Examining the shift from digital health into policy roles (02:42) Assessing political headwinds for the healthcare industry (03:27) How Medicaid cuts squeeze the commercial employer market (05:04) Reactions to the make health tech great again movement (06:33) The lack of clear standards for true interoperability (07:47) Direct primary care and the limits of shoppable health (10:32) Building Collective Health (12:23) Why healthcare innovation lags behind other tech sectors (14:25) Solving product friction caused by HIPAA and Apple standards (16:52) Leveraging complexity and the pipes of healthcare as a moat (18:15) Sponsor: Arbiter(18:46) Separating AI hype from foundational data quality use cases (22:18) Merging clinical risk tolerance with product design (23:08) Breaking down the role of third party administrators (26:04) The venture capital thesis on investing in a TPA (31:31) Advice for founders tackling the underbelly of healthcare (32:42) Using patient APIs to unblind the fragmented system(37:44) Wrap | 39m 12s | ||||||
| 2/18/26 | ![]() Why longevity author Dr. Zeke Emanuel thinks you can eat the ice cream | In this episode of Lifers, Christina Farr speaks with Dr. Zeke Emanuel about his new book, Eat Your Ice Cream, which offers a sustainable alternative to the aggressive trend of health optimization. Zeke breaks down six simple, long-term habits for longevity, emphasizing that consistency and enjoyment are more vital than perfection or expensive supplements. They discuss the future of healthcare, including the impact of miracle drugs like GLP-1s and the need for better wellness education within the medical community. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR:This episode is brought to you by Arbiter. As Michelle says: "We don't need another instrument for the orchestra—we need to conduct the orchestra." Backed by one of the largest early funding rounds in health tech, Arbiter creates one real-time source of truth from fragmented healthcare systems, then routes referrals and handles prior auths so patients actually get to care. Learn more at https://www.arbiter.ai/ —LINKS: Eat Your Ice Cream: Six Simple Rules for a Long and Healthy Life: https://wwnorton.com/books/9781324117537 Zeke’s website: https://www.ezekielemanuel.com/ Zeke’s Tiktok: https://www.tiktok.com/@drezekielemanuel CMS Elevate: https://www.cms.gov/priorities/innovation/innovation-models/maha-elevate Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Zeke:https://www.linkedin.com/in/zeke-emanuel-6ab78a1b0/ https://x.com/ZekeEmanuel Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(00:54) Intro(02:43) The inspiration behind the book (04:38) The importance of socialization and shared meals (07:51) Sustainability versus the short-term hustle (08:48) The truth about supplements and regulation (12:22) Sponsor: Arbiter(12:58) Research on psychedelics and mental health (14:52) Social determinants of health and environment (17:20) Diet essentials and the problem with ultra-processed foods (20:53) The science and practice of intermittent fasting (23:21) GLP-1 drugs as a breakthrough in healthcare (27:39) Building healthy food habits in children (30:21) Political policy and chronic illness (34:12) Four ways to prevent cognitive decline (37:52) Addressing the gap in medical education (42:05) Where to get the book(42:21) Wrap | 43m 38s | ||||||
| 2/10/26 | ![]() Dr. Robert Wachter on why healthcare is finally ready for its "giant leap" because of AI | In this episode of Lifers, Christina Farr sits down with Dr. Bob Wachter, Chair of the Department of Medicine at UCSF and author of the seminal book The Digital Doctor. After years of observing the "hope, hype, and harm" of health technology, Dr. Wachter discusses his new book, A Giant Leap, and why he has moved from a skeptic to a staunch optimist regarding AI's role in medicine. They dive into the high-stakes reality of autonomous AI, the "incumbency advantage" of companies like Epic, and why the primary care crisis makes AI integration an absolute necessity. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR:This episode is brought to you by Arbiter. As Michelle says: "We don't need another instrument for the orchestra—we need to conduct the orchestra." Backed by one of the largest early funding rounds in health tech, Arbiter creates one real-time source of truth from fragmented healthcare systems, then routes referrals and handles prior auths so patients actually get to care. Learn more at https://www.arbiter.ai/. —LINKS: Robert Wachter, MD’s website: https://www.robertwachtermd.com/ The Digital Doctor (book): https://www.amazon.com/Digital-Doctor-Hope-Medicines-Computer/dp/1260019608/ A Giant Leap (book): https://www.amazon.com/gp/product/B0F7G3216X Utah & Doctronic Partnership: https://commerce.utah.gov/2026/01/06/news-release-utah-and-doctronic-announce-groundbreaking-partnership-for-ai-prescription-medication-renewals/ (Study) 27h/day is needed to provide adult primary care: https://mhcc.maryland.gov/mhcc/pages/home/workgroups/documents/pcw/Revisit_Time_Needed_Provide_Adult_Prim_Care_032723.pdf Lifers episode with Niyum Gandhi: https://a16zstudios.slack.com/archives/C06U4ASHPR8/p1770108617302019 Bob’s Substack: https://substack.com/@robertwachter Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Bob:https://www.linkedin.com/in/robert-wachter-3102b963/ https://x.com/Bob_Wachter Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(00:42) Intro(01:04) Is AI truly different from previous healthcare technologies(02:43) Addressing the perception of AI as a crutch in medicine(04:46) The risks and realities of physician de-skilling(05:11) Moving from skepticism to optimism in digital health(05:51) Navigating AI implementation within fee-for-service payment models (07:01) How AI could potentially lower the cost of care(10:15) Advice for the next generation of doctors in the AI era(14:14) Sponsor: Arbiter(14:45) Comparing the safety of self-driving cars to AI in medicine(15:34) Analyzing Utah's pilot for autonomous medication renewals (26:04) Value-based care as an accelerator for AI adoption(28:18) The creative process and challenges of writing about AI(31:15) The growing threat of deep fakes in medical communication(31:57) Predicting the winners between startups and tech giants like Epic(34:58) Thoughts on the launch of OpenAI’s ChatGPT Health(38:40) Wrap | 42m 18s | ||||||
| 2/3/26 | ![]() Niyum Gandhi, CFO of Mass General Brigham & Mike Desjadon, CEO of Anomaly: Why hospitals are increasingly falling into the red | This week on Lifers, Niyum Gandhi, CFO of Mass General Brigham, and Mike Desjadon, CEO of Anomaly, discuss the financial pressures facing health systems today. They cover why hospital expenses are rising faster than revenue, what health systems actually look for when evaluating startups, and why collaboration matters more than finger-pointing. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3—SPONSOR:This episode is brought to you by Arbiter. As Michelle says: "We don't need another instrument for the orchestra—we need to conduct the orchestra." Backed by one of the largest early funding rounds in health tech, Arbiter creates one real-time source of truth from fragmented healthcare systems, then routes referrals and handles prior auths so patients actually get to care. Learn more at https://www.arbiter.ai/. —LINKS: Mass General Bringham: https://www.massgeneralbrigham.org/en Anomaly: https://www.findanomaly.com/ Lifers: How money really flows in healthcare with Claimable CEO Warris Bokhari & Anomaly CEO Mike Desjadon: https://www.youtube.com/watch?v=mxuZ889ww-I Sachin Jain Episode: https://www.youtube.com/watch?v=Tvtakm7NMnI Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Niyum:https://www.linkedin.com/in/niyum-gandhi/ https://x.com/niyumgandhi Mike:https://www.linkedin.com/in/mike-desjadon-4a0a21a/ https://x.com/Mike_Desjadon Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Preview(01:24) Intro(02:28) How Niyum and Mike first met at Mount Sinai(05:55) Career path and the move to CFO of Mass General Brigham(11:53) Why choose a career in healthcare(15:19) Sponsor: Arbiter(15:50) Current financial state of American health systems(19:28) Addressing the revenue and expense trend gap(21:26) The role of AI and technology in productivity(26:07) Ambient documentation and physician burnout(29:58) Strategic partnerships versus point solution vendors(31:40) The evolution of healthcare startups and health systems(36:31) Advice for founders building in the industry(40:34) Wrap | 45m 37s | ||||||
| 1/13/26 | ![]() Dr. Kameron Matthews & Inlightened President Shelli Pavone on saving primary care from collapse | Dr. Kameron Matthews (Chief Health Officer, Impact Care) and Shelli Pavone (President & Co-Founder, Inlightened) join Chrissy Farr to tackle healthcare's biggest challenges: the Medicaid crisis, state licensing chaos, the death of primary care, and why Silicon Valley keeps getting it wrong. — Join Christina for an upcoming webinar: * 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE * 5/21 - The case for building an AI native electronic health record system - https://streamyard.com/watch/RCVSNheSPePs * 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS * 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR:This episode is brought to you by Inlightened.Healthcare innovation doesn’t fail for lack of ideas; it fails when real clinical expertise is missing. Inlightened connects innovators with vetted, diverse healthcare professionals for paid research, advisory, and consulting work, helping companies build solutions grounded in reality. Healthcare professionals can sign up to share their expertise and get paid, and companies can directly access expert insights at getinlightened.com. —LINKS: Inlightened:https://www.linkedin.com/company/getinlightened/ https://www.facebook.com/getinlightened/ https://twitter.com/GetInlightened Doctors getting multiple licenses: https://www.cnbc.com/2019/10/13/telemedicine-doctors-are-getting-licenses-in-all-50-states.html Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Kameron: https://www.linkedin.com/in/kameronmatthews/ Shelli:https://www.linkedin.com/in/shelli-pavone-a729b2/ https://x.com/shellipavone Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS:(00:00) Intro(01:24) Health equity and policy landscape(03:15) Challenges in healthcare delivery(05:21) Medicaid and community health(08:49) Entrepreneurship and innovation in healthcare(12:35) Licensing and regulatory hurdles(19:28) Encouraging the next generation(23:46) The role of social media in healthcare(32:32) AI and the future of primary care(36:17) Rapid fire round(43:48) Wrap | 45m 22s | ||||||
| 1/6/26 | ![]() Sachin Jain, CEO of SCAN on why healthcare doesn’t need more toxic positivity | This week on Lifers, Christina Farr sat down with Sachin Jain, CEO of SCAN Health Plan. Sachin makes a compelling case for "radical common sense" in healthcare—the idea that we've normalized dysfunction for so long that simple, patient-centered solutions now feel revolutionary. He challenges the industry's toxic positivity and truth-telling problem, arguing that real change requires leaders to acknowledge what's broken in their own backyards, including calling out his own insurance industry publicly. — Join Christina for an upcoming webinar: • 5/19 - What will AI do for employer healthcare and benefits with Garner Health - https://streamyard.com/watch/sQfWpwRzMqWE • 6/3 - Privacy, AI & the future of HIPAA with the former founding director of ONC - https://streamyard.com/watch/bzW4sh8WAPyS • 6/23 - Not everyone can access the top 1% of physicians. Will AI change that? - https://streamyard.com/watch/qY9td6fhiXK3 —SPONSOR:This episode is brought to you by Arbiter. As Michelle says: "We don't need another instrument for the orchestra—we need to conduct the orchestra." Backed by one of the largest early funding rounds in health tech, Arbiter creates one real-time source of truth from fragmented healthcare systems, then routes referrals and handles prior auths so patients actually get to care. Learn more at https://www.arbiter.ai/. —LINKS: SCAN Health Plan: https://www.thescangroup.org/ LinkedIn post: https://www.linkedin.com/posts/sachinhjain1_the-revolution-healthcare-actually-needs-activity-7402346091767398400-CVnF?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAWcjXgBb3Jw6dX16PD9lRJSsxfgqVAqZLw The Revolution Healthcare Actually Needs: Radical Common Sense (Forbes): https://www.forbes.com/sites/sachinjain/2025/12/03/radical-common-sense-a-leadership-philosophy-for-healthcare-system/ Health Insurance is Broken ad: https://www.youtube.com/watch?v=q7bty0M9ySA Chrissy Farr’s Website: https://www.chrissyfarr.com/ Subscribe to the Second Opinion Newsletter: https://secondopinion.media/ Chrissy’s Book: The Storyteller's Advantage: https://www.chrissyfarr.com/books Lifers with Christina Farr on YouTube: https://www.youtube.com/@LiferswithChristinaFarr —FOLLOW:Sachin:https://www.linkedin.com/in/sachinhjain1/ Chrissy:https://www.linkedin.com/in/christinafarr/ https://x.com/chrissyfarr —TIMESTAMPS: (00:00) Intro(02:27) Innovative solutions in healthcare(04:28) Challenges in healthcare communication(06:06) The broken culture of healthcare leadership(14:10) Mentorship and career advice(18:02) Sponsor: Arbiter(18:33) Concierge medicine and longevity(23:05) The system's shortcomings and individual choices(24:38) Medical anxiety and consumerism in healthcare(25:35) The role of primary care physicians(26:07) AI in healthcare: opportunities and limitations(29:48) Employer-sponsored health insurance issues(35:20) The cost crisis and technological challenges(40:13) The role of social media in healthcare leadership(44:49) Wrap | 46m 13s | ||||||
Showing 25 of 67
Sponsor Intelligence
Sign in to see which brands sponsor this podcast, their ad offers, and promo codes.
Chart Positions
3 placements across 3 markets.
Chart Positions
3 placements across 3 markets.











![[Emergency Pod] Peptides - Part 2 with Dr. Jonathan Slotkin of Scrub Capital episode artwork](https://megaphone.imgix.net/podcasts/44639724-3a88-11f1-9c0d-abef4b43d9e8/image/4c028527c5cedaa3c7be6f91f31d12db.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress)
![[Emergency Pod] Peptides - Part 1 with Sunita Mohanty of Ultralight episode artwork](https://megaphone.imgix.net/podcasts/2e894238-3a23-11f1-8604-a3b3634ad3b1/image/d530aaba2d069cc996de2cbebbccae27.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress)












