Marathon Performance: Does high-carb fueling work?

Marathon Performance: Does high-carb fueling work?

From Normal Curves: Sexy Science, Serious Statistics by Regina Nuzzo and Kristin Sainani

February 23, 2026 · 1h 7m · Episode 25

About this episode

This episode explores the science behind carbohydrate fueling for marathon performance and uncovers inconsistencies in statistical reporting.

How many carbs do you need to run your best marathon? Recent headlines suggest that 120 grams per hour is the magic number. But what’s the science behind that claim? To find out, we dug into the study fueling the hype — and were surprised by what we found. In this episode, we uncover numbers that mysteriously shift after peer review, figures that don’t match the text, and p-values that refuse to line up with their confidence intervals. Along the way, we swap bonking stories, revisit repeated-measures ANOVA, renew our antipathy for spreadsheets, and follow a trail of statistical termites to a surprisingly happy scientific ending. Statistical topics Article in press vs final publication Data management and workflow Multiple testing P-values and confidence intervals Repeated Measures ANOVA Statistical sleuthing Version control in research Within-person study design Methodological morals “Everyone makes statistical mistakes, not everyone fixes them.” “If the numbers aren't consistent, Excel is often part of the story.” “If a p-value doesn't survive the trip from text to figure, there's a problem.” Statistical Sleuthing Extended Notes References Ravikanti S, Silang KG, Martyn HJ, et…

People in this episode

Hosts: Regina Nuzzo, Kristin Sainani

Topics covered

  • marathon performance
  • carbohydrate fueling
  • statistical analysis
  • peer review
  • data management
  • repeated measures ANOVA

Keywords

  • carbohydrates
  • marathon
  • p-values
  • confidence intervals
  • statistical mistakes
  • data analysis

Mentioned in this episode

Books & works: J Appl Physiol, 13C-labelled glucose–fructose

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