2. GLP-1s & Metabolic Health in Perimenopause & Menopause with Ann Konkoly, WHNP-BC

About this episode

Dr. Rachel Pope discusses GLP-1 medications and metabolic health in perimenopause with expert Ann Konkoly.

Weight frustration in perimenopause isn't just about vanity—it's about a physiological shift that changes how our bodies handle fuel. In this episode, Dr. Rachel Pope sits down with midlife health expert Ann Konkoly [https://www.kultivatewomenshealth.com/] to demystify GLP-1 medications (like Ozempic and Zepbound), the hidden dangers of visceral fat, and why the scale is often a "shitty measurement" for your actual health. In this episode, we discuss: * The "Middle" Mystery: Why the "eat less, move more" mantra fails women in perimenopause and how this transition impacts weight maintenance. * GLP-1s Beyond Weight Loss: Ann explains the metabolic benefits of these medications, including reducing neuroinflammation and protecting the heart and kidneys. * The Hidden Danger of Visceral Fat: Why a "normal BMI" can be misleading and how internal fat affects your risk for chronic disease. * Synergy with MHT: How optimizing cardiovascular health can create a safer "on-ramp" for starting hormone replacement therapy. * Preserving Lean Muscle: Strategies for "muscle-centric medicine" to ensure weight loss doesn't come at the expense of your strength and bone density. * The HOMA-IR Hack: A…

People in this episode

Host: Dr. Rachel Pope

Guest: Ann Konkoly

Topics covered

• GLP-1 medications
• metabolic health
• perimenopause
• visceral fat
• hormone replacement therapy
• muscle preservation
• insulin resistance

Keywords

• perimenopause
• metabolic health
• GLP-1
• visceral fat
• hormone therapy
• insulin resistance
• weight management
• chronic disease

Mentioned in this episode

Organizations: Kultivate Women's Health

Products: Ozempic, Zepbound

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• 6. Testosterone in Perimenopause & Menopause with Dr. Tami Rowen · March 16, 2026 · 23 min
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