Anna Krook - exercise timing. Performance Around the Clock episode 37.

About this episode

This episode features Professor Anna Krook discussing her research on exercise timing and its effects on insulin and glucose regulation in Type 2 diabetes.

Episode 37 of the Performance Around the Clock comes from the XVIII Congress of the European Biological Rhythms Society in Lubeck, Germany. We welcome Professor Anna Krook, a Professor of Integrative Physiology at the Department of Physiology and Pharmacology and chair of the Strategic Research Programme in Diabetes at Karolinska Institutet. Professor Krook is an internationally recognized leader in metabolism, skeletal muscle and insulin biology. In this episode, we discuss Professor Krook’s research journey, which began with her Ph.D. work on insulin and the insulin receptor gene, identifying rare mutations that cause severe inherited insulin resistance. She then focused on the dysregulation of insulin action seen in Type 2 diabetes, noting that muscle is the main site where insulin action goes wrong. The conversation dives into the fascinating role of the circadian clock in regulating insulin, glucose, and muscle. Dr. Krook explains that while healthy muscle mitochondria show a functional rhythm that peaks in the afternoon, this crucial rhythm is absent in muscle cells from people with Type 2 diabetes. We cover her landmark study showing that for type 2 diabetic men doing…

People in this episode

Host: Dr. Satchin Panda

Guest: Anna Krook

Topics covered

• exercise timing
• insulin biology
• Type 2 diabetes
• circadian rhythms
• metabolism
• high-intensity interval training

Keywords

• exercise timing
• insulin resistance
• Type 2 diabetes
• circadian clock
• high-intensity interval training
• blood glucose control
• muscle mitochondria

Mentioned in this episode

Organizations: Karolinska Institutet

Places: Lubeck, Germany

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