S1, E32 - Matt Truppo, PhD: AI-Driven Drug Discovery at Sanofi

About this episode

Matt Truppo discusses the advancements and challenges of AI in drug discovery at Sanofi.

AI in drug discovery has been long on promise and short on delivery. Matt Truppo, Global Head of Research Platforms and Computational R&D at Sanofi, presents a different picture. His team used AI to identify 10+ novel drug targets in 12 months, screen 30 million target combinations in days, and produce AI-designed compounds with 75% synthesizability. But Truppo is equally candid about the gaps: data integration, explainability, and change management remain real barriers. In Part 1 of this two-part conversation, hosts Steve Labkoff and Leon Rozenblit explore what happens when AI moves past pilot projects into core pharmaceutical science.

People in this episode

Hosts: Steven Labkoff, Leon Rozenblit

Guest: Matt Truppo

Topics covered

• AI in drug discovery
• pharmaceutical science
• data integration
• explainability
• change management

Keywords

• AI
• drug discovery
• Sanofi
• novel drug targets
• computational R&D
• pharmaceutical science
• data integration

Mentioned in this episode

Organizations: Sanofi

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