Practically Healthy by Dr. Melina

In this episode of Practically Healthy, Dr. Melina Jampolis sits down with cognition dietitian Barbie Boules, RDN, to talk about how women can protect their brain health in midlife and beyond. They break down the real science behind menopause, hormones, cardiometabolic health, sleep, exercise, and nutrition for dementia prevention — without the biohacking hype. You’ll learn why midlife is a critical window for brain health, how everyday habits like strength training, fiber intake, and quality sleep make a difference, and what the evidence actually says about supplements, hormone therapy, and GLP-1 medications. Practical, realistic, and evidence-based — this episode is all about doable steps for a healthier brain and body. For more great brain (and body) info, follow Barbie on IG @the_cognition_dietician

In the latest episode of Practically Healthy, Dr. Melina is joined by preventive cardiologist Dr. Danielle Belardo. Dr. Belardo, founder of the Precision Preventive Cardiology Group, discusses women's heart disease, emphasizing its significance as the number one cause of death for both men and women. She highlights the historical lack of representation of women in clinical trials, risk factors/modifiers like pregnancy and menopause that are unique to women, and the robust data guiding risk reduction for women. Dr. Belardo stresses the importance of lifestyle interventions, including dietary fiber and reduced saturated fat, and the role of statins in preventing heart disease and dementia, which is more common in women than men. She also advises all women to know their numbers (blood pressure, blood sugar, and cholesterol) and monitor them closely, especially during menopause. For more information and advice from Dr. Belardo, follow her on IG @daniellebelardomd or visit her website www.precisionpreventivecardiology.com

Dr. Janese Laster, a quadruple board-certified gastroenterologist, obesity medicine and nutrition specialist discusses the impact of processed foods and emulsifiers on gut health. She explains that emulsifiers, such as polysorbate 80 and carrageenan, make foods shelf-stable but can disrupt the gut's mucosal layer, leading to inflammation and symptoms like bloating and constipation. Laster emphasizes the importance of fiber and natural sweeteners over artificial ones. She also highlights the role of GLP-1 in appetite regulation and weight management, noting that a balanced diet rich in fiber, protein, and healthy fats can naturally boost GLP-1 levels. Laster advises against artificial sweeteners and stresses the importance of whole foods for gut health.

In this episode, Dr. Melina is joined by physician, chef, author and founder of Brain Health Kitchen Annie Fenn MD. Dr. Fenn discusses the shocking statistics about Alzheimer's dementia prevalence, but then she presents very encouraging statistics on how lifestyle and especially diet can dramatically decrease risk of Alzheimer's disease and dementia, especially if dietary changes are started early. The doctors discuss touch on the role of genetics and dementia and then jump into the top 10 brain health foods and nutrients, including choline, flavanoids and omega 3 fatty acids as well as cooking methods that can reduce your risk of Alzheimer's disease. If you have a family history of dementia, or are just interested in protecting your brain health, this episode is a must listen! Follow Dr Fenn at brainhealthkitchen.substack.com or on IG @brainhealthkitchen

There is no one size fits all for weight loss, and not everyone will respond the same to specific diets, lifestyle changes, and medications, including Ozempic. In this episode of Practically Healthy, Dr Melina welcomes world renowned gastroenterologist and obesity expert Andres J. Acosta, M.D., Ph.D. Dr. Acosta is the head of the Precision Medicine for Obesity Laboratory at Mayo Clinic and co-founder of Phenomix Sciences, a precision medicine company that uses your DNA to predict your response to weight loss interventions. The doctors discuss the four obesity phenotypes that Dr Acosta and colleagues have identified: Hungry Brain, Hungry Gut, Emotional Hunger, and Slow Burn and how using these phenotypes to create personalized treatment plans including diet, exercise and medication, can double weight loss. To learn more about this exciting new testing, visit myphenometest.com

Described as the world’s first “triple threat” in the food and medicine space, Nutritional Psychiatrist, trained chef and international best seller, Dr. Uma Naidoo joins Dr. Melina for a very special 50th episode of the Practically Healthy podcast. Dr. Naidoo shares her expert perspective on mental health through the lense of nutritional psychiatry- more simply, “your mind on food”. Dr. Naidoo reframes food as a “tool” and empowers listeners to use nutrition to help mitigate conditions from depression, anxiety and libido to bipolar disorder. She discussed foods “you should embrace” and foods "you should step back from” as prescriptive tools to match each specific condition. Dr. Naidoo shares wisdom from her groundbreaking new book, Calm Your Mind With Food which provides actionable strategies to help empower and guide the reader to mitigate anxiety through food. Tune in to learn Dr. Naidoo’s nemonic, CALMS, which lists her top recommended foods to help calm the mind. The episode closes with a Practically Healthy potato chip “swap" from Dr. Naidoo- you won’t want to miss this tip! To learn more about Dr. Naidoo, visit her website umanaidoomd.com or follow her @drumanaidoo. Purchase her new book, “Calm Your Mind With Food” on her website or everywhere books are sold.

Dr. David Katz, specialist in Internal Medicine, Preventive Medicine/Public Health, and Lifestyle Medicine joins on episode 48 of the Practically Healthy podcast to share his vast knowledge about HOW TO EAT for healthy vital people on a healthy, vital planet. The doctors discuss their perspectives on health- how “living healthfully” can be perceived as a full time job, their shared objective of adding not only years to life, but life to years, and shift the perspective of “health” as being much more than “the absence of disease”. Dr. Katz reminds listeners of the diminished state of the planet including soil deterioration, poor air quality, aquifer degradation and more. He highlights the three lenses through which he determines how we should eat: impact on human health, potential cruelty/abuse to animals and planetary impact/ environmental footprint. Tune in to learn the number one food he recommends we cut back on. The doctors share the 6 Pilars of lifestyle medicine: feed, forks, fingers, sleep, stress and love- and discuss how bundling Pilars creates opportunities for further healthy lifestyle behaviors. The doctors share their best practical tips for healthy living- tune in to hear these life changing hacks! To learn more about Dr. Katz or his company Diet ID, visit davidkatz.com or dietID.com. Dr. Katz’s wife’s nutritious and delicious recipes for busy families can be found at Cuisinity.com

Nearly HALF of all Americans don’t get enough MAGNESIUM from food- the essential nutrient involved in over 600 enzymatic reactions throughout the body. Dr. Melina welcomes America’s Favorite Food Scientist, Dr. Taylor Wallace to episode 46 of the Practically Healthy podcast to talk about the important nutrient needed by every cell in your body. Dr. Wallace shares the many benefits of magnesium including supporting brain health, bone health, helping lower blood pressure, and regularity. Studies suggests magnesium additionally supports sleep, mitochondrial function, mood and PMS, though more research is needed. Dr. Melina shares that magnesium is one of the essential nutrients her new company, Ahara is focusing on, and the doctors concur on a “food first” and supplementing if needed approach to getting the nutrients your body needs. The doctors list top food sources of magnesium, in addition to the potential benefits of specific types of magnesium supplements. Dr. Wallace shares the practical tips he employs to get more magnesium in his diet- tune in to hear his favorite oven fried chicken and spinach salad recipe! To learn more about Dr. Wallace, follow him @drtaylorwallace.

Live longer and live better through science- Dr. Kara Fitzgerald joins on episode 44 of the Practically Healthy podcast to share that “our genes are not our destiny” and the implications of her groundbreaking scientific trial showing biological age reversal in humans. The doctors explain the difference between chronological age (your age in years) and biologic age- the age of your cells that determines why people may have a more youthful appearance, feel younger and most importantly, a lower risk of every major disease, since aging is the biggest contributing factor for each. Dr. Fitzgerald explains that DNA methylation is one of the main ways we influence which genes get "turned on” and “turned off”, which is influenced by lifestyle factors. By favorably influencing DNA methylation, we can not only reduce biological age, but increase our health span and lifespan. You’ll learn the top methylation accelerators including drinking alcohol, lack of sleep, stress along with methylation decelerators- exercise, quality sleep, decreasing sedentary activity and nutrition which is one of the most powerful ways to influence methylation. The doctors highlight a food first approach and share foods (including herbs and spices!) that help slow aging and maximize your genetic potential- tune in to hear their top recommends! Learn more about Dr. Fitzgerald and her body of work at drkarafitzgerald.com or follow @drkarafitzgerald. Dr. Fitzgerald also hosts a podcast called “New Frontiers in Functional Medicine, Longevity, Epigenetics” where she discussed the science and research behind medicine, longevity, epigenetics and more.

Sex, relationships, intimacy, connection and more! Dr. Melina welcomes Dr. Ish Major, board certified psychiatrist and host of WE tv's Marriage Bootcamp for a New Year’s relationship reboot on episode 42 of the Practically Healthy podcast!The doctors dive in and outline the healthy aspects of relationships and touch on our need for love and connection as human beings. Dr. Ish explains how to assess if/ where the problems may be in your relationship by debunking your ABMs- Assumptions, Biases and Mindset- and what you should do when you don’t like what you hear.He explains one of the biggest misconceptions of married people- thinking that they shouldn’t have any problems- and instead urges them to have the courage to have hard conversations. He reveals the surprising reason why men cheat, when to consider divorce and shares practical ways that someone can be more in tune with their true self.Dr. Melina shares listener questions and the relationship guru addresses concerns ranging from reframing your mid-life baggage, having sex on the third date, and why going silent for 18 seconds with a partner might just amaze you- tune in for the fascinating answers!To learn more about Dr. Ish Major, follow him @dr_ish_major.

Dr. David Friedman, syndicated TV and radio host, best selling author and part time comedian doesn’t perform surgery as a chiropractic neurologist, but he still manages to leave his patients in stitches- HA! He joins Dr. Melina on episode 40 of the Practically Healthy podcast to invoke a good belly laugh or two and share how laughter is indeed, the best medicine.Dr. Friedman reminds the listener that humans laugh before they speak and asserts that laughter is in all of us. The doctors discuss the incredible, science-backed benefits of laughter including: decreasing inflammation, increasing infection-fighting antibodies, helping prevent heart disease and cancer and improving cognitive function. Dr. Friedman explains that laughter decreases cortisol levels which can lead to weight loss through a decrease in stressful eating and belly fat. Dr. Friedman shares that laughter can burn calories and that 20 seconds of a good belly laugh is equivalent to 100 sit ups- incredible! Dr. Friedman shares how he uses humor to bring humanity back to medicine and bond with his patients. His prescription for laughter- don’t let your stressors define you and “fake it till you partake it”. He shares that the brain doesn’t know the difference between a fake or real smile, so get grinning!The doctors show their silly sides and giggle through Keto jokes, saber tooth tiger recipes and fart anecdotes. The episode closes with practical tips to help the listener bring laughter back into their life. A lighthearted, feel-good episode that will surely bring a smile to your face. All proceeds from Dr. Friedman’s new book, “Funny Bones” go to Laughter Saves Lives Foundation, visit funnybonesbook.com for your copy. Listen to Dr. Friedman’s podcast at ToYourGoodHealthRadio.com or follow him @drdfriedman.

Ever feel like you look or feel much younger (or older) than you actually are? You might be right! Founder and Director of Operations at TruDiagnostic joins episode 38 of the Practically Healthy podcast to chat all things epigenetics- how your behaviors and environment affect the way your genes work- and how relatively new scientific breakthroughs allow us to measure and influence factors that impact our biologic age (how old we are on a cellular level compared to how old we actually are.) Hannah opens the podcast by providing the listener with an understanding of epigenetics and assures us that “your DNA is not your destiny”. Dr. Melina and Hannah discuss DNA methylation and how it can “turn on” or “turn off” certain genes from working. Unlike chronological age, biological age more accurately reflects classic signs of aging, from wrinkles and energy levels to diabetes and disease. Hannah shares the backstory behind developing TruDiagnostic and explains how to use their test to measure your TruAge (biologic age) as well as your TruAge PACE (pace of aging per chronologic year). Dr. Melina and Hannah discuss the lifestyle factors that can influence your biologic age including: dietary choices, caloric restriction, exercise, and stress management, as well as practically healthy hacks for those of us who are short on time. Hannah share her number one supplement recommendation for turning back the biologic clock and also reveals Dr. Melina’s TruAge and TruAge PACE- tune in to hear the fascinating results! An empowering and important episode for anyone looking to extend their health span and lifespan based on the latest scientific developments! To learn more about TruDiagnostics or discover your TruAge, visit TruDiagnostics.com or follow Hannah @everythingepigenetics.

Nutrition Science PhD and Professor of Medicine at Stanford, Dr. Christopher Gardner joins to share his expertise as a 20+ year academic leading headline making studies investigating the potential health benefits of various dietary components and food patterns. Dr. Gardner acknowledges the complexities of nutrition studies and urges the listener to seek “instead of” and “with what” vs “nutrition answers”. The doctors discuss topical dietary choices including red meat vs alternative meat products- how do they compare with regard to cardiovascular risk factors, TMAO levels, blood pressure and more. Low fat vs low carb diets- which is more effective for weight loss? And keto vs Mediterranean- which is better for blood sugar control and which is better for lowering LDL cholesterol? Dr. Gardner shares the results of the largest and longest-ever study comparing Atkins, Zone, LEARN and Ornish diets with regard to changes in cardiometabolic risk factors and weight loss- tune in to hear the fascinating findings! And though certain diets are better for certain people, genetics is likely NOT to blame for your weight loss struggles! A rare opportunity to hear science-based nutrition guidance from one of Dr. Melina’s most respected nutrition colleagues! To learn more about Dr. Gardner, visit https://profiles.stanford.edu/christopher-gardner