
Quest For Longevity - Improve Your Health, Slow Aging and Live a Long Life
by Tim Quin
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Recent episodes
End of Season 1
Apr 21, 2026
Unknown duration
Activate Your Longevity Genes: Fight Disease, Slow Aging & Live Longer
Apr 6, 2026
Unknown duration
GLP-1 Weight Loss Drugs Explained: Ozempic, Wegovy & Mounjaro - Results, Side Effects and Long-Term Risks
Mar 13, 2026
Unknown duration
Is Your Coffee Toxic? - The Truth About Mycotoxins & Coffee
Mar 6, 2026
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The 90 Minute Coffee Rule: Why You Shouldn't Drink Coffee First Thing In The Morning
Feb 22, 2026
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| Date | Episode | Description | Length | ||||||
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| 4/21/26 | ![]() End of Season 1 | Just me Tim Quin, saying a huge thank you for listening to the podcast throughout this first season of Quest For Longevity. I hope it has helped you discover new ways to stay healthy, stay active and live longer. Some big changes to the format of the podcast coming in season 2 and I hope you'll join me to experience them. Listen to this episode and I'll tell you all about what's coming. Social Channels Threads: https://www.threads.com/@timquin0 WhatsApp: https://whatsapp.com/channel/0029Vb7jPjNCRs1kXPBMz341 Facebook: https://www.facebook.com/QuestLongevity X: https://x.com/timquin0 Instagram: https://instagram.com/timquin0 TikTok: https://tiktok.com/timquin1 | — | ||||||
| 4/6/26 | ![]() Activate Your Longevity Genes: Fight Disease, Slow Aging & Live Longer | Can you slow the aging process by activating your longevity genes? In this episode we break down the science behind six key longevity genes — including FOXO3, sirtuins, TERT, APOE, IGF-1, and CETP — and explain what they do inside your body. We then cover the evidence-backed lifestyle habits that activate them: zone 2 cardio, resistance training, intermittent fasting, sleep optimisation, stress reduction, and targeted supplementation including NMN, omega-3, and vitamin D. Whether you're new to longevity science or already invested in your healthspan, this episode gives you practical tools to start slowing biological aging today. Build your longevity knowledge: your next listen Chronic Inflammation: What it is, why it's bad, and what you can do to avoid it Autophagy: Your Disease Fighting, Life-Extending Super Power Intermittent Fasting: What Is It, How Does It Work and Is It Right For You? The Mediterranean Diet Explained: How To Lose Weight & Get Healthy Longevity Genes Research Sources FOXO3 and Longevity FOXO3A Genotype Is Strongly Associated with Human Longevity FOXO3 – A Major Gene for Human Longevity (PMC) Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies Sirtuins and NAD+ It Takes Two to Tango: NAD+ and Sirtuins in Aging/Longevity Control NAD+ and Sirtuins in Aging and Disease (NIH/PMC) Sirtuins and Their Biological Relevance in Aging and Age-Related Diseases Telomeres, TERT and Exercise Exercise Delays Aging: Evidence from Telomeres and Telomerase Physical Activity and Telomere Length: Impact of Aging and Potential Mechanisms Telomeres, Lifestyle, Cancer, and Aging (NIH/PMC) Stress, Mindfulness and Telomere Length Can Meditation Slow Rate of Cellular Aging? Cognitive Stress, Mindfulness, and Telomeres (PMC) Wandering Minds and Aging Cells – Epel, Blackburn et al. IGF-1, Fasting and Protein Protein Quantity and Source, Fasting-Mimicking Diets, and Longevity (NIH/PMC) Fasting-Mimicking Diet and Markers/Risk Factors for Aging, Diabetes, Cancer, and Cardiovascular Disease Mediterranean Diet The Mediterranean Diet and Cardiovascular Health – Circulation Research Long-Term Impact of Mediterranean Diet on Cardiovascular Disease Prevention – PubMed Inflammaging Chronic Inflammation and the Hallmarks of Aging (NIH/PMC) Inflammageing: Chronic Inflammation in Ageing, Cardiovascular Disease, and Frailty Inflammation and Aging: Signaling Pathways and Intervention Therapies – Nature Sleep and the Glymphatic System The Glymphatic System Clears Amyloid Beta and Tau from Brain to Plasma in Humans – Nature Communications The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices (PMC) Social Channels Threads: https://www.threads.com/@timquin0 WhatsApp: https://whatsapp.com/channel/0029VbBpYR2Chq6NOqlcGT0T Facebook: https://www.facebook.com/TimothyQuin X: https://x.com/timquin0 Instagram: https://instagram.com/timquin0 TikTok: https://tiktok.com/timquin1 | — | ||||||
| 3/13/26 | ![]() GLP-1 Weight Loss Drugs Explained: Ozempic, Wegovy & Mounjaro - Results, Side Effects and Long-Term Risks | GLP-1 weight loss drugs like Ozempic, Wegovy and Mounjaro are transforming obesity treatment. But how do GLP-1 injections actually work? How much weight can you lose, what are the side effects, how much do they cost, and what happens when you stop taking semaglutide? In this episode we examine the evidence behind GLP-1 medications, their risks, benefits and long-term impact on health. Common GLP-1 Weight Loss Drug Questions Answered in This Episode What are GLP-1 and GIP drugs and what are they doing inside my body? How much weight could I lose on GLP-1 drugs? What are the benefits of taking GLP-1 drugs? What are the risks of taking GLP-1 medication? Will GLP-1 injections cause my muscles to waste? How much do GLP-1 drugs cost? Should I take GLP-1 weight loss drugs? Weight Loss Drugs – Timestamps 00:00 – Do you struggle to lose weight? 03:55 – Common questions about weight loss drugs 05:31 – What are GLP-1 drugs and how do they work? 08:25 – How much weight could I lose on weight loss jabs? 11:47 – What are the risks of taking GLP-1 weight loss drugs? 13:53 – Can GLP-1 weight loss injections cause muscle wastage? 17:29 – Should I take GLP-1 weight loss drugs? 19:08 – What happens when I stop taking GLP-1 weight loss medication? 20:33 – How much do GLP-1 weight loss jabs cost? 22:24 – The future of weight loss medication 24:25 – GLP-1 weight loss drugs summary GLP-1 Weight Loss Drugs Research Sources How GLP-1 Drugs Work & Clinical Effectiveness Once-Weekly Semaglutide in Adults with Overweight or Obesity — New England Journal of Medicine Semaglutide for the Treatment of Overweight and Obesity: A Review — PMC Cardiovascular & Kidney Benefits Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT Trial) — New England Journal of Medicine Clinical Outcomes of Tirzepatide or GLP-1 Receptor Agonists in Individuals With Type 2 Diabetes — PMC/JAMA Network Open Tirzepatide Slowed Progression of Chronic Kidney Disease in Patients with Type 2 Diabetes — American Diabetes Association Side Effects & Safety Considerations and Interactions with GLP-1 Receptor Agonists — NHS Specialist Pharmacy Service GLP-1 Agonists — Diabetes UK Weight-Loss Injections Explained — British Heart Foundation Muscle Loss & Sarcopenia Muscle Mass and GLP-1 Receptor Agonists: Adaptive or Maladaptive Response to Weight Loss? — Circulation (AHA) Changes in Lean Body Mass with GLP-1-Based Therapies and Mitigation Strategies — PubMed Impact of GLP-1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia — PubMed Weight Regain After Stopping Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension — PMC New Study Finds Stopping Weight-Loss Drugs Is Linked to Faster Regain Than Ending Diet Programmes — University of Oxford Fake & Counterfeit Drugs Warning About Sharp Rise in Illegal Medicines Sold in the EU — European Medicines Agency Fake Ozempic: WHO Warns of Falsified Semaglutide Sold Online — Medical News Today WHO Recognition of Obesity as a Chronic Disease & GLP-1 Guidance WHO Issues Global Guideline on the Use of GLP-1 Medicines in Treating Obesity Social Channels WhatsApp: https://whatsapp.com/channel/0029VbBpYR2Chq6NOqlcGT0T Facebook: https://www.facebook.com/TimothyQuin X: https://x.com/timquin0 Instagram: https://instagram.com/timquin0 YouTube: https://youtube.com/timquin0 TikTok: https://tiktok.com/timquin1 | — | ||||||
| 3/6/26 | ![]() Is Your Coffee Toxic? - The Truth About Mycotoxins & Coffee | Is Your Coffee Making You Sick? - The Truth About Mycotoxins in Coffee You've probably seen the hype — "mouldy coffee," "toxic beans," "your morning cup is slowly poisoning you." But is there any truth to it, or is it just clever marketing designed to sell you expensive "clean" coffee? In this episode, we cut through the noise and take an evidence-based look at mycotoxins in coffee. We cover what mycotoxins actually are, why ochratoxin A (OTA) and aflatoxins keep coming up, and what independent studies really show about contamination levels in green, roasted, and instant coffee. We also look at what happens during roasting and brewing — and why the mould found on raw coffee beans tells a very different story to what ends up in your cup. Plus, how EU food safety regulations and maximum limits for ochratoxin A apply to the coffee you buy every day, and whether low-mycotoxin or mould-free coffee is worth the premium. If you're a health-conscious coffee drinker wondering whether to switch brands, ditch instant, or invest in specialty coffee, this episode gives you the practical, no-hype breakdown you need. You'll learn the following about mycotoxins and coffee What mycotoxins are and how they form on coffee beans Whether roasting destroys mycotoxins How your total dietary mycotoxin load matters more than coffee alone Simple storage tips to keep your coffee as clean as possible Mycotoxin-Free Coffee Suppliers The truth about mycotoxins in coffee. Do we really need to avoid them? Organic Coffee Beans (Lab-tested, Mould & Chemical Free) Focus | Organic Coffee Beans | Mycotoxin Free - Lab Tested | Freshly Roasted Mycotoxin Free Coffee: How the Mule keeps your beans clean Organic Coffee, Mycotoxin Free Clean & Pure | Lean caffeine Bulletproof Coffee & Mycotoxins | Big Island Coffee Roasters Research Sources: Mycotoxins & Coffee Prevalence of toxigenic fungi and mycotoxins in Arabic coffee (Coffea arabica): Protective role of traditional coffee roasting, brewing and bacterial volatiles - PMC Mycotoxins in green coffee: Occurrence and risk assessment - ScienceDirect Mycotoxins | EFSA Prevalence of toxigenic fungi and mycotoxins in Arabic coffee (Coffea arabica): Protective role of traditional coffee roasting, brewing and bacterial volatiles | PLOS One Social Channels WhatsApp: https://whatsapp.com/channel/0029VbBpYR2Chq6NOqlcGT0T Facebook: https://www.facebook.com/TimothyQuin X: https://x.com/timquin0 Instagram: https://instagram.com/timquin0 TikTok: https://tiktok.com/timquin1 | — | ||||||
| 2/22/26 | ![]() The 90 Minute Coffee Rule: Why You Shouldn't Drink Coffee First Thing In The Morning | Why You Should Wait 90 Minutes Before Drinking Coffee In The Morning Are you struggling with that mid-afternoon energy crash? In this episodeI look into the science of caffeine timing and why reaching for your morning coffee the moment you wake up might be sabotaging your focus and energy levels. We dive into the "90-minute rule" to explain how delaying your first cup helps align with your body's natural cortisol levels and circadian rhythm. You'll learn how adenosine build-up causes that dreaded afternoon slump and I share some simple morning hacks to boost your natural energy without caffeine first thing. Key Caffeine Takeaways: The link between cortisol spikes and caffeine tolerance. How to clear adenosine naturally to prevent a midday slump. Practical tips for staying alert before your first brew. Stop the cycle of caffeine crashes and optimize your energy. This one hack might transform your energy levels! 90 Minute Coffee Delay Research Sources Source articles I referenced to help produce this episode about delaying your morning coffee: Huberman Lab: Caffeine Science and Timing Strategies Houston Methodist: Is There a Best Time to Drink Your Coffee? PMC: Caffeine Stimulation of Cortisol Secretion ScienceDaily: Drink Coffee After Breakfast, Not Before Oura Ring: Should You Delay Your Morning Caffeine? News-Medical: Caffeine Timing Guide Social Channels WhatsApp: https://whatsapp.com/channel/0029VbBpYR2Chq6NOqlcGT0T Facebook: https://www.facebook.com/TimothyQuin X: https://x.com/timquin0 Instagram: https://instagram.com/timquin0 YouTube: https://youtube.com/timquin0 TikTok: https://tiktok.com/timquin1 | — | ||||||
| 2/16/26 | ![]() The Paleo Diet Explained: How To Lose Weight & Get Healthy: Weight Loss Diets Mini-Series - Part 4 | The Paleo Diet Explained: Can Eating Like Our Ancestors Help You Lose Weight? Curious about the Paleo diet and whether it's right for you? In this episode, I look into one of the world's most popular eating plans that promises weight loss and better health by eating like our prehistoric ancestors. Here's What You'll Learn About The Paleo Diet: What is the Paleo diet and how does it work? The evolutionary mismatch hypothesis behind Paleo nutrition Complete Paleo diet food list: what you can and can't eat Scientific evidence on Paleo for weight loss, blood sugar control, and heart health Practical tips for following a Paleo lifestyle (or modified Paleo approach) How Paleo compares to other popular diets Whether you're looking for a structured diet plan to lose weight, reduce inflammation, improve blood sugar, or to simply eat more whole foods and fewer processed foods, this episode gives you the facts you need to decide if Paleo could be the diet for you. Perfect for: Anyone interested in weight loss diets, ancestral eating, low-carb nutrition, gluten-free living, or understanding how evolutionary biology may influence modern health and chronic disease prevention. Paleo Diet Timestamps 02:00 What is The Paleo Diet? 02:35 Who Started The Paleo Diet? 03:20 Paleo Diet Theory 05:23 What Can You Eat on The Paleo Diet? 06:33 What Can't You Eat On The Paleo Diet? 07:36 Is The Paleo Diet Good For Weight Loss & Health? 09:55 How Easy Is It To Do The Paleo Diet? 11:10 Does The Paleo Diet Work? 12:29 Paleo Diet Key Takeaways Paleo Guides and Diet Plans Some useful resources if you want to learn more about the paleo diet and are thinking about giving it a try. A Beginner's Guide - How to Start a Paleo Lifestyle Plan – Kevin's Natural Foods The Paleo Diet — A Beginner's Guide + Meal Plan Paleo recipes | Good Food Paleo Diet Research Sources A list of resources I used to compile this episode on the paleo diet. Paleolithic Diet - StatPearls - NCBI Bookshelf The Paleolithic Diet - PMC Paleo diet: What is it and why is it so popular? - Mayo Clinic Paleo diet still lacks evidence - PMC Is the Paleo diet safe for health and the environment? - ScienceDirect History of The Paleo Diet Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me X: https://x.com/TimQuin0 | — | ||||||
| 2/3/26 | ![]() The Keto Diet Explained: How To Lose Weight & Get Healthy: Weight Loss Diets Mini-Series - Part 3 | Keto Diet Explained: How It Works, What to Eat & Is It Right for You? The keto diet has become an increasingly popular way to lose weight. In this bite-sized episode I explore how the keto diet works, what foods you can and can't eat, and whether this popular low-carb, high-fat diet is right for your weight loss goals. In this episode, we break down: What the keto diet is and how ketosis works Foods to avoid on keto (sugars, grains, most fruits, starchy vegetables) What you can eat on the ketogenic diet (meat, fish, eggs, low-carb vegetables, healthy fats) Keto diet pros and cons for weight loss and health Practical tips for starting keto, including meal planning and avoiding "keto flu" Why food quality matters as much as carb counting Whether you're considering keto for weight loss, better appetite control, or metabolic health, this episode provides science-backed information and practical advice to help you decide if the ketogenic diet fits your lifestyle. Perfect for anyone interested in low-carb diets, sustainable weight loss, and evidence-based nutrition strategies. Topics covered: ketogenic diet, keto for beginners, low-carb diet, weight loss diets, ketosis, keto meal planning, keto food list, healthy eating, nutrition tips Keto Diet - Episode Timestamps 02:04 - What Is the Keto Diet? 03:46 - What Foods Can You Not Eat on The Keto Diet? 05:54 - What Foods Can You Eat on The Keto Diet? 07:23 - Keto Diet Pros And Cons 08:49 - Keto Diet Practical Advice 11:05 - Keto Diet Key Takeaways Keto Diet Beginner Guides Great intro to the keto diet: A Keto Diet for Beginners: The #1 Ketogenic Guide Go a little deeper into keto and learn about the potential wider benefits of following a keto diet: The Ketogenic Diet: A Detailed Beginner's Guide to Keto Nice easy video intro to keto: A Beginner's Guide to the Keto Diet A comprehensive guide to Keto: https://www.ruled.me/guide-keto-diet/ Keto Diet Meal Plans A good 14-day keto meal plan to get you started on the right foot: 14-Day Keto Meal Plan with Recipes & Shopping Lists - Diet Doctor Mouth watering keto recipes 🤤: 47 Easy Keto Dinner Recipes Everyone In The Family Will Love A comprehensive list of foods you can eat on the keto diet: The Complete Keto Food List (Printable PDF!) - Wholesome Yum Useful shopping list, showing how many grams of carbs are in common foods: The Complete Keto Grocery List (With Free PDF) Keto Diet Research Sources If you want to do deeper research into the ketogenic diet, including some of the potential mental and physical benefits, here are some good papers to read: The ketogenic diet has the potential to decrease all-cause mortality without a concomitant increase in cardiovascular-related mortality | Scientific Reports The Ketogenic Diet: Clinical Applications, Evidence-based Indications, and Implementation - StatPearls - NCBI Bookshelf Pilot study shows ketogenic diet improves severe mental illness The impact of ketogenic diet on some metabolic and non‐metabolic diseases: Evidence from human and animal model experiments - PMC | — | ||||||
| 1/29/26 | ![]() The Mediterranean Diet Explained: How To Lose Weight & Get Healthy: Weight Loss Diets Mini-Series - Part 2 | The Mediterranean Diet Explained The Mediterranean diet is widely recognised as one of the healthiest ways to eat and it is followed by some of the healthiest and longest-lived people in the world. Following the Mediterranean diet could provide some incredible health benefits for you too, while also helping you lose weight in a controlled and sustainable way. I explore how the Mediterranean diet could help you lose weight and why it is renowned for its health benefits. I also offer some practical guidance for anyone wanting to try the Mediterranean diet. Part 2 of my diet mini series, exploring different approaches to healthy eating and sustainable weight loss. If you want to dive deeper, here is a practical Mediterranean Diet Guide. If you are a vegetarian, here are some amazing diet recipes that you can follow on a Vegetarian Mediterranean Diet. Mediterranean Diet - Show Quicklinks 01:15 Introduction to The Mediterranean Diet 02:43 How Does The Mediterranean Diet Work? 03:58 Can the Mediterranean Diet Help You Lose Weight? 05:43 How to Follow The Mediterranean Diet? 08:21 Is The Mediterranean Diet Good For Vegitarians? 08:47 My Thoughts On the Mediterranean Diet Mediterranean Diet Research Sources The Mediterranean Diet and Cardiovascular Health - PubMed The Mediterranean diet: health, science and society - PubMed Mediterranean diet linked to longevity, say Harvard researchers Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study - PubMed Mediterranean diet in the management and prevention of obesity - PubMed Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me X: https://x.com/TimQuin0 | — | ||||||
| 1/20/26 | ![]() The 5:2 Diet Explained - How To Lose Weight & Get Healthy: Weight Loss Diets Mini-Series - Part 1 | Learn about the 5:2 diet in this bite-sized guide. If you want to lose weight and improve your heath this popular intermittent fasting approach might be what you are looking for. I touch on the science behind intermittent calorie restriction, practical tips for following the diet, potential health benefits, including improved blood sugar control and heart health, and who should avoid this eating plan. Perfect for anyone wondering if the 5:2 diet is right for their weight loss journey. This episode is part of my weight loss diet mini series, exploring different approaches to healthy eating and sustainable weight loss. Take a look at this article if you want to dive deeper into the 5:2 diet. Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me Facebook: https://www.facebook.com/TimothyQuin/ X: https://x.com/TimQuin0 Research Sources The Fast Diet Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial | Lifestyle Behaviors | JAMA Internal Medicine What is the 5:2 diet? | Good Food | — | ||||||
| 1/16/26 | ![]() US Dietary Guidelines VS UK Dietary Guidelines | The US has just released new dietary guidelines, and there have been some welcome updates since the last edition. More emphasis on protein, a friendlier stance on full-fat dairy, and explicit warnings about ultraprocessed foods reflect advances in research and our understanding of nutrition. But how does this compare with the somewhat outdated UK government dietary guidelines, issued way back in 2016? In this episode, we compare the new US guidelines with the UK's Eatwell Guide. We look at where they agree, where they differ, and what these differences actually mean for how you eat. From protein targets to the processing debate, we break down the practical takeaways you can use, whether you're trying to maintain muscle as you age, feed your family well, or just understand what "eating healthy" actually looks like in 2026. Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me X: https://x.com/TimQuin0 Research Sources Dietary Guidelines For Americans The Eatwell Guide - Public Health England Food-based dietary guidelines - United Kingdom New US dietary guidelines call for more protein, less processed food - BBC News | — | ||||||
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| 1/7/26 | ![]() 5 Very Simple Steps to Better Health in 2026 | Show Description The start of a new year often comes with big health goals, bold promises, and plenty of noise. In this episode of Quest for Longevity, Tim cuts through the hype and shares five simple, evidence-based ways to improve your health in 2026. You'll learn practical strategies to support weight loss, fitness, energy, and healthy aging — including how to move more and build strength, eat more protein and fibre for better metabolic and gut health, improve sleep quality, reduce stress, and create habits that actually stick. Rather than extreme diets, supplements, or quick fixes, this episode focuses on realistic lifestyle changes backed by science that support long-term health and longevity. If you're looking for a clear, trustworthy guide to starting the year in a healthier, more sustainable way, this episode is a great place to start. Probiotic and Prebiotic Food Cheat Sheet X: https://x.com/TimQuin0/status/2009002017356951844?s=20 Facebook: https://www.facebook.com/TimothyQuin Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me X: https://x.com/TimQuin0 Facebook: https://www.facebook.com/TimothyQuin/ Instagram: https://www.instagram.com/timquin0/ Research Sources Here is a list of sources I consulted to help me produce this episode of Quest For Longevity: Breathing Practices for Stress and Anxiety Reduction (PMC) — a peer-reviewed article summarizing how controlled breathing influences autonomic nervous system activity and supports stress and anxiety reduction. https://pmc.ncbi.nlm.nih.gov/articles/PMC10741869/ Effect of breathwork on stress and mental health: A meta-analysis (Nature) — evidence that structured breathwork interventions can improve stress and mental-health outcomes, though research design matters. https://www.nature.com/articles/s41598-022-27247-y The Role of Protein Intake and its Timing on Body Composition and Muscle Function in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials — a comprehensive review showing that increased protein intake improves lean body mass and muscle function, which are key to healthy ageing. https://pubmed.ncbi.nlm.nih.gov/32232404/ Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults — meta-analytic evidence that higher daily protein intake contributes to gains in lean body mass and muscle performance. https://pubmed.ncbi.nlm.nih.gov/35187864/ Higher dietary fibre intake is associated with increased skeletal muscle mass and strength in adults aged 40 years and older — research linking greater fibre intake with higher lean mass, better body composition, and muscle strength, which supports functional health as we age. https://pubmed.ncbi.nlm.nih.gov/34585852/ What Happens to Your Body When You Eat 30 Grams of Fiber Every Day — a recent overview explaining how higher fibre intakes improve digestion, satiety, cholesterol, and blood sugar control. https://www.eatingwell.com/benefits-of-eating-30-grams-of-fiber-every-day-11872775 Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis — this meta-analysis shows that around 7,000 steps per day is linked with significantly lower risk of mortality and major diseases compared with very low step counts, making daily movement both evidence-based and achievable. https://www.sciencedirect.com/science/article/pii/S2468266725001641 Sleep regularity is a stronger predictor of mortality risk than sleep duration — research demonstrating that both sleep consistency and adequate duration are linked with lower premature mortality risk and improved cardiometabolic outcomes. https://academic.oup.com/sleep/article/47/1/zsad253/7280269 Sleep and healthy aging: A systematic review and path forward — a broad review showing associations between positive sleep indicators (e.g., adequate, consistent sleep) and healthy aging outcomes. https://pmc.ncbi.nlm.nih.gov/articles/PMC9585152/ Breathing Practices for Stress and Anxiety Reduction (PMC) — a peer-reviewed article summarizing how controlled breathing influences autonomic nervous system activity and supports stress and anxiety reduction. https://pmc.ncbi.nlm.nih.gov/articles/PMC10741869/ Effect of breathwork on stress and mental health: A meta-analysis (Nature) — evidence that structured breathwork interventions can improve stress and mental-health outcomes, though research design matters. https://www.nature.com/articles/s41598-022-27247-y | — | ||||||
| 1/3/26 | ![]() Gut Health Explained & How to Fix Your Gut in 2026 | Show Description There is an increasing amount of buzz around gut health right now, so I decided to dive in and find out why. In this episode, I explore what the gut is, what gut health means and why it matters far more than you might think. And most importantly, what we can do, starting today, to improve our gut health through simple dietary and lifestyle changes. Quality Health Supplements If you're looking for quality health supplements I can highly recommend WeightWorld. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Connect With Me Facebook: https://www.facebook.com/TimothyQuin/ Instagram: https://www.instagram.com/timquin0/ X: https://x.com/TimQuin0 Research Sources The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health - PMC A comprehensive review of the gut-brain axis and how gut microbiota influences neurotransmitter production, including serotonin, and its connection to mood disorders like anxiety and depression. Gut microbiota's effect on mental health: The gut-brain axis - PMC Explores the bidirectional communication between the gut microbiota and the central nervous system, and the role of dysbiosis in mental illnesses. The microbiome in autoimmune diseases - PMC Discusses how gut microbiome dysbiosis plays a role in autoimmune diseases including rheumatoid arthritis, Crohn's disease, and multiple sclerosis, and how the microbiome regulates immune system development and function. Emerging role of gut microbiota in autoimmune diseases - Frontiers in Immunology Examines how gut microbiota influences autoimmune disease onset and progression through immune cell regulation and intestinal barrier function. Fermented-food diet increases microbiome diversity, decreases inflammatory proteins, study finds - Stanford Medicine Groundbreaking Stanford research showing how a diet rich in fermented foods enhances microbiome diversity and reduces inflammation markers. Dietary Fiber Intake and Gut Microbiota in Human Health - PMC Reviews how dietary fiber is fermented by gut microbiota to produce beneficial short-chain fatty acids and how fiber intake modulates microbiome structure and diversity. Harvard gut discovery could change how we treat obesity and diabetes - ScienceDaily Recent 2025 research from Harvard identifying gut-produced metabolites that influence liver function and insulin sensitivity, with implications for obesity and diabetes treatment. Exploring the Gut Microbiota: Key Insights Into Its Role in Obesity, Metabolic Syndrome, and Type 2 Diabetes - The Journal of Clinical Endocrinology & Metabolism Comprehensive 2024 review examining how gut microbiota composition differs in people with obesity and diabetes, and the role of bacterial diversity in metabolic health. | — | ||||||
| 11/26/25 | ![]() Collagen: What Does It Do & Are Supplements Worth The Money? | Do collagen supplements live up to the hype? This evidence-based episode cuts through the marketing claims to reveal what science really says about collagen supplements. We explore what collagen is, how it works in your body, and examine the latest clinical trials and meta-analyses on skin health, joint pain, bone density, and muscle function. Perfect for anyone considering collagen or wanting to understand the science behind this billion-dollar industry. Quality Health Supplements I use WeightWorld supplements. They produce great value, quality products and I've been very pleased with the results. (I am affiliated with WeightWorld and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you any extra and anything I earn helps me to devote more time to researching and producing this podcast.) Research Sources Collagen: What It Is, Types, Function & Benefits Biochemistry, Collagen Synthesis - StatPearls The Collagen Family Collagens—structure, function, and biosynthesis Collagen Collagen Type I Collagen - an overview A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver in situ Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals Collagen Powder Absorption And Bioavailability Does Collagen Powder Survive Digestion? Absorption Explained How Collagen Works Inside Your Body: The Science Behind Absorption Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12‐Week Oral Intake of a Supplement Containing Hydrolysed Collagen Clinical studies and meta-analysis on the effects of collagen, vitamin, and nutrient supplementation for the rejuvenation of collagenic fibers: a systematic review Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials Are Collagen Supplements Helpful for Arthritis? Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge Can collagen supplements help improve skin and soothe joint pain? The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review Efficacy of collagen peptide supplementation on bone and muscle health: a meta-analysis Efficacy of collagen peptide supplementation on bone and muscle health: a meta-analysis Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study Expert consensus on specific collagen peptides in osteoporosis management Collagen Peptide Supplementation and Musculoskeletal Performance: A Systematic Review and Meta-Analysis Collagen Science Update – March 2024 Edition Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers Collagen Type II (native): Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study Collagen Types: The Important Differences Between I, II & III Differences and benefits between hydrolyzed collagen and collagen Dr. Brad Stanfield: Collagen has No benefits for skin aging? | — | ||||||
| 11/9/25 | ![]() Autophagy: Your Disease Fighting, Life-Extending Super Power | Autophagy is the body's natural recycling system that cleans out damaged cells and renews them from within. We'll look at how this built-in process helps slow aging, boosts energy, and protects against disease, and how simple habits like fasting, exercise, and quality sleep can help switch it on. No extreme diets or complicated science — just practical ways to support your body's own repair system and live a longer, healthier life. Connect With Me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Research Sources A Comprehensive Review of Autophagy and Its Various Roles in Health and Disease — https://pmc.ncbi.nlm.nih.gov/articles/PMC6678135/ PMC Autophagy: cellular and molecular mechanisms — https://pmc.ncbi.nlm.nih.gov/articles/PMC2990190/ PMC An Overview of Autophagy: Morphology, Mechanism, and Regulation — https://pmc.ncbi.nlm.nih.gov/articles/PMC3894687/ PMC Autophagy-Dependent Beneficial Effects of Exercise — https://pmc.ncbi.nlm.nih.gov/articles/PMC5538402/ PMC Autophagy genes in biology and disease | Nature Reviews Genetics — https://www.nature.com/articles/s41576-022-00562-w Nature Autophagy and Aging: Maintaining the Proteome through Exercise, Nutrients & mTORC1 — https://pmc.ncbi.nlm.nih.gov/articles/PMC6351830/ PMC Autophagy in health and disease: A comprehensive review — https://www.sciencedirect.com/science/article/pii/S0753332218309053 ScienceDirect Beneficial effects of intermittent fasting: a narrative review — https://e-jyms.org/journal/view.php?doi=10.12701%2Fjyms.2022.00010 e-jyms.org Autophagy: Definition, Process, Fasting & Signs – Cleveland Clinic — https://my.clevelandclinic.org/health/articles/24058-autophagy Cleveland Clinic The effect of fasting or calorie restriction on autophagy induction — https://www.sciencedirect.com/science/article/pii/S1568163718301478 ScienceDirect Physical Exercise and Selective Autophagy: Benefit and Risk — https://www.mdpi.com/2073-4409/8/11/1436 | — | ||||||
| 11/5/25 | ![]() Health & Longevity Insight: Metabolic Disease & Dementia, Eat 5-A-Day For Better Sleep, AI Prostate Cancer Diagnosis | Join me as I unpack the latest science and developments shaping the future of health and longevity. This week on the Quest Health & Longevity Insight: Discover how getting your 5-a-day could improve your sleep, how the power of AI is poised to revolutionise prostate cancer diagnoses, and why managing metabolic health in mid-life could protect your brain from dementia in your later years. Connect With Me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Research Sources Scientists say this simple diet change can improve sleep fast | ScienceDaily Higher daytime intake of fruits and vegetables predicts less disrupted nighttime sleep in younger adults NHS to offer same-day prostate cancer diagnosis - BBC News Role of age and exposure duration in the association between metabolic syndrome and risk of incident dementia: a prospective cohort study - The Lancet Healthy Longevity | — | ||||||
| 11/1/25 | ![]() Rosehip Supplements: What Are They & What Are The Health Benefits? | In this episode, I dive into the research on rosehips. This ancient remedy has shown impressive results in osteoarthritis trials, and even emerging studies on metabolism nerve damage. Are the claims about it's benefits overhyped or is this humble supplement worth adding to your stack? Connect With Me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Research Sources Therapeutic Applications of Rose Hips from Different Rosa Species Effects of Daily Intake of Rosehip Extract on Low-Density Lipoprotein Cholesterol and Blood Glucose Levels: A Systematic Review Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trial Unveiling the effects of Rosa canina oligosaccharide liposome on neuropathic pain and motor dysfunction following spinal cord injury in rats: relevance to its antioxidative effects Dietary rose hip exerts antiatherosclerotic effects and increases nitric oxide-mediated dilation in ApoE-null mice Rose Hip | — | ||||||
| 10/17/25 | ![]() Chronic Inflammation: What it is, why it's bad, and what you can do to avoid it | Chronic Inflammation: The Silent Epidemic Quietly Killing 60% of Adults Learn how to reduce chronic inflammation naturally and discover the difference between acute and chronic inflammation in this comprehensive guide to the hidden health crisis affecting nearly half of all adults. Chronic Inflammation Symptoms and Treatment Explained Uncover what causes chronic inflammation in the body and the shocking connection between this "silent epidemic" and modern killers, including heart disease, Type 2 diabetes, cancer, Alzheimer's disease, and stroke—responsible for up to 60% of global deaths. What You'll Learn Signs of chronic inflammation and how to reverse it through evidence-based lifestyle interventions How to test for chronic inflammation at home using C-reactive protein (CRP) biomarker testing The chronic inflammation and weight loss connection: why excess fat actively produces inflammatory molecules Best anti-inflammatory foods to eat: omega-3 fatty fish, berries, turmeric, leafy greens, and whole grains A chronic inflammation action plan and foods to avoid including refined sugars, trans fats, and AGEs (advanced glycation end products) The chronic inflammation and autoimmune disease link, affecting conditions like rheumatoid arthritis and inflammatory bowel disease Lifestyle changes to reduce chronic inflammation: exercise protocols, sleep optimization, and stress management techniques Whether you're seeking chronic inflammation symptoms and treatment options or want to prevent inflammatory diseases before they develop, this episode delivers actionable strategies backed by scientific research. Chronic Inflammation Topics Covered Anti-inflammatory diet, inflammation biomarkers, immune system health, disease prevention, longevity, metabolic health, cardiovascular disease prevention, cancer risk reduction To find out if you might be suffering from chronic inflammation, a C-reactive protein (CRP) test is a good place to start. You can get a quality home test kit from OneDayTests.com using the link below and a 10% discount using the exclusive code "Quest10". OneDayTests.com: https://onedaytests.com/products/c-reactive-protein-crp-blood-test Use this code for a 10% discount on eligible test kits: Quest10 Quality Health Supplements I use WeightWorld supplements. They produce great value, quality products and I've been very pleased with the results. (I may be affiliated with brands mentioned here and receive a small commission if you buy via my link or use my checkout code. This doesn't cost you extra and anything I earn helps me to devote more time to researching and producing this podcast.) Meditation & Mindfulness Apps Calm: https://www.calm.com/ Headspace: https://www.headspace.com/ Chronic Inflammation Action Plan (Google Doc) Connect With Me X: https://x.com/TimQuin0 Research Sources Chronic Inflammation - StatPearls - NCBI Bookshelf UK Inflammation Crisis 2 in 5 Britons Affected 2025 Chronic Inflammation is now the silent epidemic causing 60% global adult deaths: Cause, symptoms, and treatment - The Economic Times Chronic inflammation messes with your mind. Here's how to calm it | New Scientist Advanced Glycation End Products and Risks for Chronic Diseases: Intervening Through Lifestyle Modification Discovering Inflammation in Atherosclerosis: Insights from Pathogenic Pathways to Clinical Practice The Role of Inflammation in Cancer: Mechanisms of Tumor Initiation, Progression, and Metastasis Inflammatory Trajectory of Type 2 Diabetes: Novel Opportunities for Early and Late Treatment The Relationship Between Chronic Inflammation and Diabetes-Related Heart Complications - CVRTI Adipose Tissue as an Endocrine Organ | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic Obesity and inflammation: the linking mechanism and the complications - PMC Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity - PMC Weight Loss Benefits for Arthritis Elevated Inflammatory Markers in Response to Prolonged Sleep Restriction Are Associated With Increased Pain Experience in Healthy Volunteers | — | ||||||
| 10/7/25 | ![]() Creatine For Brain Health: Does It Boost Memory and Cognitive Function? | Discover the Surprising Cognitive Benefits of Creatine Supplementation Can creatine improve your brain power? While creatine is famous for building muscle and enhancing athletic performance, emerging research suggests this popular supplement may also boost cognitive function, improve memory, and protect against age-related mental decline. What You'll Learn About Creatine and The Brain in This Episode: How creatine works in the brain - Understanding ATP energy, the blood-brain barrier, and brain metabolism Clinical research on creatine and cognition - What studies reveal about memory, focus, and mental performance Who benefits most from creatine - Sleep-deprived individuals, vegetarians, vegans, and older adults Optimal creatine dosage for brain health - The difference between 5g and 25g daily doses Safety and side effects - Long-term considerations and what the research shows Creatine for aging and mental fatigue - Can it keep your brain sharp as you get older? Is Creatine the Ultimate Brain-Boosting Supplement? I cut through the hype and examine the real science behind creatine supplementation for cognitive enhancement. From ATP energy production to neuroprotection, learn whether creatine deserves a place in your supplement stack for brain health. This Episode On How Creatine Effects The Brain Is Perfect For: Fitness enthusiasts curious about cognitive benefits Anyone interested in nootropics and brain supplements Vegetarians and vegans looking to optimise mental performance Older adults seeking natural ways to support brain health Biohackers exploring science-backed supplements Quality Creatine Supplements I Use I use WeightWorld creatine supplements. They produce great value, quality products and I've been very pleased with the results. Creatine Monohydrate Powder (simply mix with water and drink): https://tracking.comfortclick.eu/SHOFA Creatine Monohydrate Tablets (super convenient if you're on the move): https://tracking.comfortclick.eu/SHOFC Creatine Monohydrate Gummies (super convenient and a tasty treat): https://tracking.comfortclick.eu/SHOFD (I may be affiliated with these brands and receive a small commission if you buy via my link. This doesn't cost you more and anything I earn helps me to devote more time to researching and producing this podcast.) Creatine and The Brain Research Sources - Effects of Creatine Supplementation on Brain Function and Health - PMC - Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation | Scientific Reports - Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials - Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review - ScienceDirect - Benefits of Creatine Supplementation for Vegetarians Compared to Omnivorous Athletes: A Systematic Review - PMC Connect With Me X: https://x.com/TimQuin0 | — | ||||||
| 9/30/25 | ![]() Vitamin K2: The Quiet Nutrient Protecting Hearts & Strengthening Bones | Vitamin K2 might just be the most important nutrient you've never heard of. In this episode of Quest Biohacking, we uncover this quiet powerhouse, a vitamin that helps direct calcium to our bones and teeth and away from our arteries, helping prevent dangerous plaque buildup. We'll dive into the science showing how it supports heart health, bone strength, and even plays a role in metabolism and emerging cancer research. And with modern diets leaving most of us deficient, we'll explore how adding more vitamin K2 could be a simple, powerful step toward healthier aging. Connect With Me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Vitamin K2 Research Sources Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study The Role of Vitamin K2 in Bone and Cardiovascular Health Vitamin K2 – a neglected player in cardiovascular health: a narrative review Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study Six months supplementation with vitamin K may slow progression of arterial stiffness but has no effect on calcification in healthy postmenopausal women Vitamin K supplementation and bone health in postmenopausal women—a randomized controlled trial Vitamin K and Bone Health: A Review Vitamin K2 Therapy for Postmenopausal Osteoporosis Vitamin K and bone health: A review of the evidence in the context of chronic kidney disease Vitamin K Intake and Periodontal Attachment Loss in the US Elderly Population: Data from NHANES 1999–2004 Vitamin K2 Level in Serum and its Association with Periodontitis: A Cross-sectional Study The Impact of Nutrition on Periodontal Health Association between Vitamin K Intake and Periodontitis in Elderly US Adults: NHANES 2009–2014 Food composition and vitamin K: A comprehensive analysis of vitamin K1 and K2 vitamers in Australian foods | — | ||||||
| 9/26/25 | ![]() Walking: The Easiest Way To Enhance Your Health, Happiness & Lifespan | Walking is one of the most powerful yet simplest biohacks for improving health and lifespan. In this episode, we explore how something as simple as putting one foot in front of the other can lower the risk of heart disease, diabetes, cancer, and dementia—while also boosting mood, memory, creativity, and sleep. Learn why walking after eating is good for you and why walking makes us feel happy. From reducing stress hormones to protecting our cells against aging, walking is something we should all be doing more of if we want to live longer, healthier and happier. Discover how many steps really matter, why pace counts, and easy ways to weave more walking into daily life. Connect With Me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Research Sources association between daily step count and all-cause and cardiovascular mortality: a meta-analysis | European Journal of Preventive Cardiology | Oxford Academic Does Physical Activity Increase Life Expectancy? A Review of the Literature - Reimers - 2012 - Journal of Aging Research The Effects of Postprandial Walking on the Glucose Response after Meals with Different Characteristics - PMC Impact of post-meal and one-time daily exercise in patient with type 2 diabetes mellitus: a randomized crossover study | Diabetology & Metabolic Syndrome Exercising to Relax - Harvard Health Publishing Stanford study finds walking improves creativity Low-intensity daily walking activity is associated with hippocampal volume in older adults - PMC Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis - The Lancet Public Health Walk faster, live longer: How just 15 minutes a day can boost lifespan | ScienceDaily Daily Step Count and Depression in Adults: A Systematic Review and Meta-Analysis | Public Health | JAMA Network Open Can brisk walking reduce your biological age? - BHF The relationship between mitochondrial function and walking performance in older adults with a wide range of physical function - PMC Telomeres and Mitochondrial Metabolism: Implications for Cellular Senescence and Age-related Diseases - PMC | — | ||||||
| 9/10/25 | ![]() Are Cold Plunges & Cold Showers Good For You? | Do cold plunges and cold showers live up to all the hype? Can they really improve your health and potentially help you live longer? In this episode I explore the reported physical and mental benefits of cold exposure and the evidence backing them up. Plus, I'll share some practical tips for safely starting your cold therapy journey. Connect with me Facebook: https://www.facebook.com/QuestBiohacking Instagram: https://www.instagram.com/timquin0/ Research Sources Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes https://pmc.ncbi.nlm.nih.gov/articles/PMC10191861/ Repeated stress exposure results in a survival–reproduction trade-off in Drosophila melanogaster https://pmc.ncbi.nlm.nih.gov/articles/PMC2842730/#s3 Chill Your Stress Away: Exploring Vagus Nerve Cold Water Therapy for Anxiety Relief https://urbanicetribe.com/chill-your-stress-away-exploring-vagus-nerve-cold-water-therapy-for-anxiety-relief/ Cold Water Therapy and Skin Health: A Refreshing Path to Dermatological Wellness https://www.news-medical.net/health/Cold-Water-Therapy-and-Skin-Health-A-Refreshing-Path-to-Dermatological-Wellness.aspx What Are the Health Benefits of Cold Showers? https://health.clevelandclinic.org/are-cold-showers-good-for-you Cold Showers Lead to Fewer Sick Days https://hbr.org/2018/03/cold-showers-lead-to-fewer-sick-days A Sample Of Cold Plunge Options (no endorsement or affiliation) Three Degree Club https://threedegreeclub.co.uk/collections/all Polar https://polar-recovery.com/collections/ice-baths Myo Master https://myomaster.com/collections/ice-baths B&Q https://www.diy.com/departments/ice-bath-tub-spa-for-cold-water-therapy-recovery-plunge-pool-with-lid/5057102015109_BQ.prd?srsltid=AfmBOoqgGbNxe05ocTf1k81mhOytsCJ4NAWtQfK_aY0ZgmqEhBfv9zUAqXU | — | ||||||
| 9/4/25 | ![]() Is Coffee Good For You? | Is coffee good for your health? I explore coffee's impact on your body, discovering what it actually does to your system, whether caffeine is truly addictive, and the surprising health benefits of moderate coffee consumption. I examine the research on coffee and how it can help prevent disease and help us live longer. Learn why coffee is classified as a drug and why so many people are choosing to quit caffeine, despite the potential health benefits ☕ Coffee & Caffeine Q&A Guide I've tried to answer all of your questions about coffee in this guide. Please take a look 👇 https://newsletter.questbiohacking.com/p/coffee-and-caffeine-q-and-a-guide Research Sources How Caffeine Improves Exercise Performance https://www.healthline.com/nutrition/caffeine-and-exercise 9 Reasons Why (the Right Amount of) Coffee Is Good for You https://www.hopkinsmedicine.org/health/wellness-and-prevention/9-reasons-why-the-right-amount-of-coffee-is-good-for-you Adenosine, caffeine, and sleep–wake regulation: state of the science and perspectives https://pmc.ncbi.nlm.nih.gov/articles/PMC9541543/ Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism https://pmc.ncbi.nlm.nih.gov/articles/PMC6143111/ | — | ||||||
| 8/22/25 | ![]() Intermittent Fasting: What is it, how does it work and is it right for you? | Intermittent fasting is a powerful eating pattern that can promote some hugely beneficial changes in your body. This science-backed approach could help you lose weight, lower your risk of diabetes, enhance brain function, reduce inflammation, and even extend your life. I cover how intermittent fasting works and how to get started if it's something you'd like to try. I also include some useful tips and hacks for beginners, to make the transition to intermittent fasting a little easier. Research Sources Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even Without Weight Loss in Men with Prediabetes https://pmc.ncbi.nlm.nih.gov/articles/PMC5990470/ The link between intermittent fasting and insulin resistance https://simple.life/blog/intermittent-fasting-and-insulin/ Intermittent fasting and weight loss https://pmc.ncbi.nlm.nih.gov/articles/PMC7021351/ INTERMITTENT FASTING AND HUMAN METABOLIC HEALTH https://pmc.ncbi.nlm.nih.gov/articles/PMC4516560/ Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting https://pmc.ncbi.nlm.nih.gov/articles/PMC5783752/ The Effect of Fasting on Human Metabolism and Psychological Health https://pmc.ncbi.nlm.nih.gov/articles/PMC8754590/ Insulin resistance reduction, intermittent fasting, and human growth hormone: secondary analysis of a randomized trial https://www.nature.com/articles/s44324-024-00025-2#:~:text=Prolonged%20water%2Donly%20fasting%20induces,conserves%20lean%20muscle12%2C13. Water-only fasting boosts human growth hormone without weight loss https://www.news-medical.net/news/20250225/Water-only-fasting-boosts-human-growth-hormone-without-weight-loss.aspx#:~:text=The%20study%20also%20found%20that,on%20baseline%20HGH%20level%20groups. Human Growth Hormone (HGH) https://my.clevelandclinic.org/health/articles/23309-human-growth-hormone-hgh Intermittent fasting and cognitive performance – Targeting BDNF as potential strategy to optimise brain health https://www.sciencedirect.com/science/article/abs/pii/S009130222100073X#:~:text=Highlights,pre%2Dclinical%20and%20human%20studies. Autophagy: What You Need to Know https://www.healthline.com/health/autophagy The Effects of Intermittent Fasting on Brain and Cognitive Function https://pmc.ncbi.nlm.nih.gov/articles/PMC8470960/ Scientists identify how fasting may protect against inflammation https://www.cam.ac.uk/research/news/scientists-identify-how-fasting-may-protect-against-inflammation | — | ||||||
| 8/17/25 | ![]() Magnesium: What Does It Do & Should You Take a Supplement? | Magnesium is an essential mineral that quietly supports over 300 processes in the body, yet so many of us aren't getting enough. From steady heart rhythms and relaxed muscles to deeper sleep, calmer moods, and better digestion, magnesium is a true unsung hero of health. We'll explore the different forms of magnesium and discuss how to know if you might benefit from taking a supplement. You'll also learn the best ways to take magnesium, how much is safe, and simple food sources that can naturally boost your intake. Whether you're curious about sleep hacks, muscle recovery, or heart health, this episode gives you practical, science-backed information about magnesium and magnesium supplements. Research Sources Magnesium https://www.webmd.com/diet/supplement-guide-magnesium Magnesium https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ Challenges in the Diagnosis of Magnesium Status https://pmc.ncbi.nlm.nih.gov/articles/PMC6163803/ Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis https://pmc.ncbi.nlm.nih.gov/articles/PMC5786912/ Magnesium - Uses, Side Effects, and More https://www.webmd.com/vitamins/ai/ingredientmono-998/magnesium#overview Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies https://pmc.ncbi.nlm.nih.gov/articles/PMC5852744/#:~:text=Higher%20levels%20of%20circulating%20Mg,disease%20and%20coronary%20heart%20disease. Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration https://pubmed.ncbi.nlm.nih.gov/27178134/ Dirt Poor: Have Fruits and Vegetables Become Less Nutritious? https://www.scientificamerican.com/article/soil-depletion-and-nutrition-loss/ Changes in USDA food composition data for 43 garden crops, 1950 to 1999 https://pubmed.ncbi.nlm.nih.gov/15637215/ | — | ||||||
| 8/10/25 | ![]() Eggs: Are They Good Or Bad & How Many is Too Many? | Eggs have been called both a superfood and a health risk – so what's the truth? In this episode, we crack open the science on cholesterol, nutrients, and daily limits, separating myth from fact to help us decide whether eggs deserve a place on our plate… and how many. Research Sources Eggs: Are they good or bad for my cholesterol? https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/expert-answers/cholesterol/faq-20058468 Association between Egg Consumption and Cholesterol Concentration: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://pmc.ncbi.nlm.nih.gov/articles/PMC7400894/ Eggs and cholesterol https://www.bhf.org.uk/what-we-do/news-from-the-bhf/news-archive/2015/may/eggs-and-cholesterol Does eating eggs increase my risk of heart disease? https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/eggs-and-heart-disease | — | ||||||
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