The Normals | Episode 1

The Normals | Episode 1

From Science Magazine Podcast by Science Magazine

April 7, 2026 · 24 min

About this episode

The episode explores the NIH's unprecedented study of normal humans in the 1950s and the experiments conducted on them.

How do we know what's normal in a person? In the early 1950s, the National Institutes of Health (NIH) set out to do something unprecedented. It wanted to start studying normal humans on a grand scale. It had pretty much everything in place: It had the building, it had recruited all of these amazing researchers—it was the healthy human bodies NIH didn't have. How do we know what’s normal in a person? In the early 1950s, the U.S. National Institutes of Health (NIH) set out to do something unprecedented. It wanted to start to study normal humans on a grand scale. It had pretty much everything in place: It had the building, it had recruited all of these amazing researchers—it was the healthy human bodies NIH didn’t have. When the healthy subjects arrived, experimenters tested LSD, sleep devrivation, rice-only diets, and more risky intervetions on them. Where it found those volunteers and what happened next is the story of The Normals. Starting on 7 April, the Science Podcast will be releasing a new three-part limited series called The Normals. We'll hear from some of the original “Normals,” follow the program through the decades, and see what's happening with healthy human subject…

People in this episode

Host: Sarah Crespi

Guests: Laura Stark, Dale Horst, Shirley Burry Geissinger

Topics covered

  • normalcy
  • human research
  • NIH studies
  • historical research
  • LSD experiments
  • healthy subjects

Keywords

  • normal humans
  • NIH
  • LSD
  • sleep deprivation
  • healthy subjects
  • historical research
  • The Normals

Mentioned in this episode

Organizations: National Institutes of Health, Science Podcast, Center for Medicine, Health, and Society

More episodes of Science Magazine Podcast

Explore listener stats, chart rankings, contacts and more on the Science Magazine Podcast podcast page.