Untapped Potential

Untapped Potential

From Skyline Drive: How to Live Forever by iHeartPodcasts and Kaleidoscope

July 21, 2026 · 60 min · Season 2 · Episode 6

About this episode

Mangesh explores the impact of colonialism on South Asian epigenetics and longevity research while navigating personal family reflections and modern health practices.

Because the vast majority of longevity research is based on white people, Mangesh asks the question, what about HIS body? He talks with a Yale researcher from Delhi who explains how centuries of colonialism have shaped South Asian epigenetics, leading to stark inequalities—and more big questions. And then, Mangesh heads to India, where he subjects himself to high-tech services at a biohacking lab and visits a traditional ayurvedic clinic. Back home in New York, his mom reflects on life after loss, and how much longer she really wants to live. Plus: Mangesh’s teenage son explains looksmaxxing and rates his dad’s face. Learn more about Raghav Sehgal’s longevity research Check out Reverse Infinity and Shree Shanti Wellness in Goa Try a recipe for pani puri   Listen to the BBC audio documentary 3 Million , about the Bengal famine Special thanks to Azadi Records and Bliss Samsa for their beautiful tracks, and Botany for the score.  Episode collage art by Vahini Shori . See omnystudio.com/listener for privacy information.

People in this episode

Host: Mangesh

Guest: Raghav Sehgal

Topics covered

  • longevity research
  • South Asian epigenetics
  • colonialism
  • biohacking
  • ayurvedic medicine
  • family dynamics
  • looksmaxxing

Keywords

  • longevity
  • epigenetics
  • biohacking
  • ayurveda
  • colonialism
  • family
  • health
  • looksmaxxing
  • India
  • New York

Mentioned in this episode

Organizations: Yale, Reverse Infinity, Shree Shanti Wellness, Azadi Records, Bliss Samsa, Botany

Books & works: 3 Million

Places: Delhi, India, New York

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