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On the show
From 18 epsHost
Recent guests
Recent episodes
How to Lose Weight and Fix Your Metabolism in 2026 | Dr Mauricio Gonzalez
Jun 22, 2026
1h 29m 53s
Evidence-Based Exercise in Pregnancy and Postpartum | Dr Margie Davenport
Jun 15, 2026
1h 33m 07s
Nutrition for satiety and weight loss | Dr Federica Amati
Jun 9, 2026
1h 33m 33s
The Surgeon Defending Statins, GLP-1s, and Ancel Keys | Dr Terry Simpson
Jun 1, 2026
1h 42m 31s
Has Optimisation Culture Gone Too Far? | Sarah Ann Macklin
May 28, 2026
1h 10m 48s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 6/22/26 |  How to Lose Weight and Fix Your Metabolism in 2026 | Dr Mauricio Gonzalez | For decades we have treated the number on the scale as the goal of metabolic health. Dr Mauricio Gonzalez, a triple board-certified physician and endocrinology fellow practising in New York, makes the case that we have been measuring the wrong thing. In this conversation we explore why liver fat, not body weight, is becoming the real target, what the latest weight-loss medications can and cannot do, and how to cut through the hype and dogma that surround this field. What we cover: Why isolated blood tests and blood pressure readings tell you very little The myth that GLP-1 medications are "the easy way out" Why liver fat may matter more than body weight How diabetes clinics now remove medications instead of adding them Which supplements earn their place, and which Mauricio has cooled on The minimum effective dose for exercise, and knowing when "enough" is enough A grounded, practical conversation with a doctor who meets people where they are. If you enjoy the show, please take a moment to rate and review The Proof on Apple Podcasts or Spotify, it genuinely helps more people find these conversations. To connect with Dr Mauricio Gonzalez, follow him on Instagram, X, and YouTube, or visit his website at drmauriciogonzalez.com. Intro (00:00) Minimum Effective Dose for Exercise (01:38) Why Continuity of Care Reduces Mortality (07:09) How Type 2 Diabetes Silently Develops Over 12 Years (09:23) Statin vs. PCSK9 Inhibitor: How Doctors Choose (12:45) How GLP-1 Drugs Transformed the Diabetes Clinic (21:46) Why Doctors Now Measure Organ Fat, Not Body Weight (30:25) How Fatty Liver Disease Is Diagnosed (34:05) How Liver Fat Drives Insulin Resistance (40:47) Wegovy vs. Zepbound: How to Choose a GLP-1 (48:18) Should Lean People Use GLP-1s for Metabolic Health? (51:53) Why Patients Feel Guilty Taking GLP-1s (54:13) How Mauricio’s Nutrition Advice Has Evolved Over a Decade (01:04:35) Supplements on GLP-1s: What's Worth Taking (01:09:42) Minimum Effective Dose for Resistance Training (01:16:52) When Health Optimization Becomes Counterproductive (01:21:20) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand. SwimClub SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Use code THEPROOF at eightsleep.com/theproof for up to $500 off. The 4th of July sale ends July 12, and you get 30 days to try it at home and return it if you don't love it. Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland. Truemed Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars. ProLon ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF. ProLon ships within the United States. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan. | 1h 29m 53s | ||||||
| 6/15/26 |  Evidence-Based Exercise in Pregnancy and Postpartum | Dr Margie Davenport | In this episode, exercise physiologist Dr Margie Davenport walks me through what the evidence actually shows about exercise during pregnancy and the postpartum period. Margie chaired the 2019 Canadian Guideline for Physical Activity throughout Pregnancy, the 2025 Canadian postpartum guideline, and the upcoming International Olympic Committee consensus statement on athletes through pregnancy and postpartum. We cover where the 140 bpm rule came from, the scale of the benefits at the population level, what direct fetal monitoring during HIIT and heavy lifting really shows, the new postpartum data, and why so many of the historical prohibitions do not survive contact with the data. What we cover: Where the 1985 "stay below 140 bpm" rule came from, and why it has long outlived its evidence Around 40 percent fewer cases of preeclampsia and gestational diabetes, and around 67 percent fewer cases of depression during pregnancy HIIT, heavy resistance training, and what fetal monitoring shows The 51 percent reduction in complications among women who kept lifting heavy Postpartum: the six-week myth, breastfeeding and injury risk, and a 45 percent reduction in postpartum depression The short list of actual "don'ts": scuba diving, and a few situational cautions The paradigm shift from prohibition to shared decision-making If this episode is useful, please leave a rating and review on Apple Podcasts or Spotify, and share it with someone in your life who is trying to make sense of conflicting advice. To connect with Dr Margie Davenport, visit exerciseandpregnancy.ca, follow her on Instagram at @DrMargieDavenport, or find her on LinkedIn and YouTube. Intro (00:00) Why Pregnancy Exercise Advice Feels So Confusing (01:15) The Most Damaging Myth About Exercise In Pregnancy (03:08) How Exercise Cuts Pregnancy Complications By 40% (05:05) Why Pregnant Women Were Excluded From Research (07:46) Can You Do High Intensity Workouts While Pregnant (12:49) How Exercise Lowers Preeclampsia And Diabetes Risk (16:43) How Much Exercise Is Safe During Pregnancy (27:03) Is Heavy Lifting Safe During Pregnancy (32:10) What You Should Never Do While Pregnant (40:41) Pelvic Floor Exercises Every Pregnant Woman Needs (47:41) How To Know If You're Overexerting While Pregnant (56:12) Does Exercise Affect Fertility And Conception (1:00:42) Why The 140 BPM Myth Still Exists (1:04:52) How Exercise Improves Postpartum Mental Health And Sleep (1:09:28) The Truth About The 6 Week Postpartum Rule (1:11:32) Does Breastfeeding Increase Your Risk Of Injury (1:17:13) Why Pregnant Athletes Need Better Policy Support (1:19:56) What Future Pregnancy Exercise Research Will Reveal (1:24:50) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38TERA ships to the United States, Australia, and New Zealand. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com. Momentous ships to many countries worldwide depending on local import regulations. ProLon ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF. ProLon ships within the United States. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com. IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America. WHOOP WHOOP, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. WHOOP ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan. | 1h 33m 07s | ||||||
| 6/9/26 |  Nutrition for satiety and weight loss | Dr Federica Amati✨ | GLP-1 medicationsappetite and satiety+4 | Dr Federica Amati | ZOEThe Appetite Reset | — | GLP-1appetite+7 | — | 1h 33m 33s | |
| 6/1/26 |  The Surgeon Defending Statins, GLP-1s, and Ancel Keys | Dr Terry Simpson✨ | health misinformationGLP-1 medications+4 | Dr Terry Simpson | The Unfiltered MDFDA+3 | — | GLP-1statins+6 | — | 1h 42m 31s | |
| 5/28/26 |  Has Optimisation Culture Gone Too Far? | Sarah Ann Macklin✨ | wellness cultureself-compassion+4 | Sarah Ann Macklin | Healthy Shouldn’t Be This Hard | — | wellness cultureself-esteem+5 | — | 1h 10m 48s | |
| 5/26/26 |  What the Headlines Get Wrong About the Future of Meat | Bruce Friedrich✨ | meat consumptionindustrial animal agriculture+5 | Bruce Friedrich | Meat: How the Next Agricultural Revolution Will Transform Humanity's Favorite Food and Our FutureGood Food Institute+1 | 2026 | meatindustrial agriculture+5 | — | 1h 47m 40s | |
| 5/18/26 |  Improving cholesterol and blood pressure with diet | A Masterclass✨ | cholesterolblood pressure+4 | Dr Walter WillettMichelle Routhenstein+1 | Harvard | — | cholesterolblood pressure+6 | — | 1h 57m 16s | |
| 5/11/26 |  The Peptides Quietly Accelerating Aging | Dr Valter Longo✨ | peptideslongevity+5 | Dr Valter Longo | USC Longevity InstituteHarvard | — | peptidesGLP-1+8 | — | 1h 47m 36s | |
| 5/4/26 |  The Diet That Lowers Cholesterol Like a Statin | Dr Andrea Glenn✨ | plant-based nutritioncholesterol+4 | Dr Andrea Glenn | NYUHarvard T.H. Chan School of Public Health+2 | — | cholesterolplant-based diet+6 | — | 1h 35m 09s | |
| 4/28/26 |  Food Labels, Fibre, and Ultra-Processed Foods: What Really Matters | Rhiannon Lambert✨ | ultra-processed foodsnutrition+4 | Rhiannon Lambert | The Unprocessed PlateThe Fibre Formula+5 | — | ultra-processed foodsNOVA system+5 | — | 58m 32s | |
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| 4/21/26 |  The Peptide Lie: What a Drug Developer Reveals About the Compounds Everyone Is Injecting | Dr Leigh Baxt✨ | peptidesdrug development+3 | Dr Leigh Baxt | Unbiased Science | — | peptidesdrug development+5 | — | 45m 42s | |
| 4/13/26 |  Preventing and reversing osteoporosis | Dr Belinda Beck✨ | osteoporosisbone health+4 | Dr Belinda Beck | The Bone ClinicONERO | — | osteoporosisbone strength+7 | — | 1h 24m 18s | |
| 4/6/26 |  New microbiome science | Dr Tim Spector✨ | microbiome sciencefermented foods+5 | Dr Tim Spector | ZOENature | — | microbiomefermentation+7 | — | 1h 25m 47s | |
| 3/30/26 |  Food and weight loss | Dr Kevin Hall✨ | ultra-processed foodsenergy balance+4 | Dr Kevin Hall | NIHFood Intelligence: The Science of How Food Both Nourishes and Harms Us | — | ultra-processed foodsenergy density+4 | — | 1h 56m 21s | |
| 3/23/26 |  The exercise that builds strong bones and better balance | Dr Lora Giangregorio✨ | bone healthexercise+3 | Dr Lora Giangregorio | University of Waterloo | — | bone healthfractures+3 | — | 2h 37m 18s | |
| 3/16/26 |  The dietary guidelines great debate | Dr Christoper Gardner and Dr Ty Beal✨ | U.S. Dietary Guidelinesnutrition science+4 | Dr Christoper GardnerDr Ty Beal | Stanford Nutrition Studies Research Group | — | dietary guidelinesnutrition+5 | — | 2h 51m 16s | |
| 3/9/26 |  The sleep habit that quietly raises your risk of heart disease | Dr Kristen Knutson✨ | circadian healthmetabolism+5 | Dr Kristen Knutson | Northwestern Feinberg | — | circadian rhythmssleep health+5 | — | 1h 24m 35s | |
| 3/2/26 |  The Science of Exercise for Women 40+: What to Prioritise (And What to Ignore) | Dr Lauren Colenso-Semple and Dr Alyssa Olenick✨ | exercise for womenmidlife fitness+4 | Dr Lauren Colenso-SempleDr Alyssa Olenick | — | — | exercisewomen 40++5 | — | 2h 58m 55s | |
| 2/23/26 |  Building muscle for longevity | Dr Brad Schoenfeld and Alan Aragon✨ | muscle buildingprotein requirements+3 | Dr Brad SchoenfeldAlan Aragon | fitadvancement.com | — | muscle retentionprotein targets+3 | 38TERA | 3h 30m 14s | |
| 2/16/26 |  The good and the bad of the new US dietary guidelines | Dr David Katz✨ | US dietary guidelinesnutrition science+5 | Dr David Katz | Dietary Guidelines Advisory CommitteeTrue Health Initiative+1 | — | dietary guidelinesnutrition+6 | — | 1h 31m 18s | |
| 2/10/26 |  Reversing atherosclerosis with diet | Simon Hill, Msc | Can diet really reverse atherosclerosis, or is that an overpromise? Since sharing my own coronary CT angiogram results, this question has come up almost daily. In this episode, I revisit the best clinical trials to see what the evidence actually says. I break down six randomised controlled trials and explain how different dietary patterns influence plaque progression, plaque stability, and cardiovascular events. What we cover What atherosclerosis is and how it develops over time The tools used to measure plaque and artery health Evidence from six major randomised controlled trials on diet and atherosclerosis What Mediterranean and low fat diets actually achieve in practice Whether diet still matters if you are already on medication Key takeaways for prevention, progression, and long term heart health Diet cannot do everything, but the evidence shows it can meaningfully change the trajectory of atherosclerosis and reduce cardiovascular risk. Intro (00:00) What is Atherosclerosis? Understanding Plaque Buildup (02:06) 4 Ways to Measure Plaque: CAC, IMT, CTA, and QCA (05:35) The Gold Standard: 6 Randomized Controlled Trials (RCTs) (09:36) The 1990 Lifestyle Heart Trial (Dean Ornish) (12:20) The STARS Trial: Omega-3s & Fiber for Plaque Reversal (19:17) The SCRIP Trial: Stacking Lifestyle and Medication (23:36) PREDIMED Study: The Power of the Mediterranean Diet (26:53) CORDIOPREV Results: Secondary Prevention of Heart Disease (32:53) DISCO CT Trial: Modern AI Imaging of Plaque Changes (39:24) Summary of Clinical Evidence: What Actually Shrinks Plaque? (43:53) 3 Critical Takeaways for Managing Your Heart Health (46:25) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com. IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America. Pique Tea Pique’s Pu’er Tea Duo brings ancient fermentation into a simple daily ritual, delivering living nutrients that support digestion, metabolism, and sustained energy from the inside out. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON. Pique ships within the U.S. and to Australia, Canada, and select EU countries. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill | 53m 52s | ||||||
| 2/2/26 |  How body fat affects your metabolic health and risk of metabolic disease | Dr Robert Eckel | I’m joined by Dr Robert Eckel to unpack why obesity is far more complex than a BMI number and why insulin resistance plays such a central role in cardiometabolic disease. We discuss preclinical versus clinical obesity, fat distribution, metabolic risk, and what actually improves health outcomes beyond weight loss alone. What We Cover Why BMI is only a starting point Preclinical versus clinical obesity explained Why visceral fat matters more than total fat How insulin resistance develops with excess body fat Who may benefit most from weight loss interventions GLP-1 therapies, benefits and open questions A practical, evidence-based conversation that reframes how we think about obesity, risk and long term health. Introduction (00:00) Clinical vs Preclinical Obesity: How Should Obesity Be Defined? (05:21) Why Is Obesity Difficult to Diagnose and Treat in Practice? (08:06) How Genetics and Environment Influence Body Fat Gain (20:27) What Is Insulin Resistance and Metabolic Syndrome? (32:23) How Insulin Sensitivity Relates to Clinical Obesity (55:26) Why Insulin Resistance Begins in Adipose Tissue (59:49) Physiological vs Pathological Insulin Resistance Explained (01:04:47) How Physical Activity Improves Insulin Sensitivity (01:10:46) Family History, Genetics, and Cardiometabolic Risk (01:12:30) Individualised Obesity Treatment Guidelines in Clinical Care (01:15:40) How GLP-1 Receptor Agonists Are Used in Obesity Management (01:16:12) What Is the Obesity Paradox in Cardiometabolic Disease? (01:22:01) Future Projections for Obesity and Cardiometabolic Health (01:30:07) Public Health Challenges in Preventing Excess Adiposity (01:40:23) Practical Clinical Takeaways and Final Thoughts (01:44:15) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan. | 1h 53m 01s | ||||||
| 1/26/26 |  The science of fertility: Hormones, inflammation, and what you can control | Dr Natalie Crawford | Fertility is not just about timing ovulation. In this episode, Dr Natalie Crawford explains how sleep, stress, insulin resistance, diet, toxins, supplements, and lifestyle choices influence egg and sperm quality, miscarriage risk, and fertility outcomes. We cover fertility myths, evidence-based nutrition, supplements that matter, and when medical treatments like IVF or egg freezing make sense. What We Cover Sleep, inflammation, and hormone signalling Insulin resistance and reproductive health Strength training, stress, and metabolic resilience Fertility nutrition and soy myths Supplements that support fertility Sex, ovulation timing, and common misconceptions Fertility treatments and realistic expectations A practical, compassionate, and science-driven conversation for anyone planning a pregnancy or struggling to conceive. You can learn more from Dr Natalie Crawford by preordering her book The Fertility Formula at nataliecrawfordmd.com/book. You can also follow her on Instagram for ongoing fertility education, and listen to her podcast As a Woman. Intro (00:00) How Personal Loss Changed Medical Practice (03:34) Infertility, Isolation, and the Power of Support Systems (11:32) Fertility Is Not Luck: How Empowered Choices Shape Outcomes (16:03) Common Fertility Myths and Misconceptions (21:31) Sperm Health, Lifestyle, and Testosterone Risks (32:59) Chronic Inflammation and Its Impact on Reproductive Health (42:50) Egg Quality vs Age: What Really Drives Infertility (50:55) Hidden Signs of Chronic Inflammation You Shouldn’t Ignore (01:01:22) Tracking Your Menstrual Cycle as a Vital Health Sign (01:10:34) Birth Control and Fertility Awareness (01:19:17) Lifestyle Changes That Can Improve Natural Fertility (01:28:33) Why Sleep Is Critical for Hormones, Fertility, and Metabolic Health (01:34:13) Muscle Mass, Insulin Resistance, and Fertility Health (01:43:48) How Food Influences Inflammation (01:53:33) Supplements That Support Fertility and Egg Quality (02:05:56) Fertility Supplement Red Flags (02:15:55) Everyday Behavioral Toxins That Harm Fertility (02:29:46) Common Fertility Myths Explained (02:36:19) When to Consider Medical Interventions for Infertility (02:42:43) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. ProLon Just in time for the new year, ProLon’s 5-Day Fasting Mimicking Diet offers a science-backed way to support metabolic health while still allowing you to eat. ProLon is offering The Proof listeners 15% off their 5-day nutrition program at ProLonLife.com. Caraway Caraway’s cookware set is a favourite for a reason. It can save you up to $190 compared to buying items individually, and The Proof listeners can take an additional 10% off at CarawayHome.com or by using code THEPROOF at checkout. Caraway. Non-toxic cookware made modern. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill | 3h 06m 44s | ||||||
| 1/19/26 |  Why some people gain weight eating the same food | Dr Karen Corbin | Could your gut microbiome influence how many calories you absorb from the same food? Karen Corbin explains the science behind energy absorption, faecal calorie loss, and why feeding your microbes may support metabolic health. We also cover practical diet upgrades, the reality on probiotics, and where microbiome research is heading next, including metabolite signatures and gut–brain links. What We Cover How the microbiome may change calorie absorption and energy balance Why fibre and resistant starch matter, and how to increase them Where “lost” calories go, and what microbial biomass could mean Probiotics vs prebiotics: what is worth your time and money How fast microbiome changes can happen with diet The future: metabolites, objective diet measures, and brain health research Thanks for listening. If you enjoyed it, share the episode and subscribe for more evidence-based conversations. You can keep up with Dr Karen Corbin’s latest research by connecting with her on LinkedIn and exploring her profile at the AdventHealth Research Institute. Intro (00:00) Can the Gut Microbiome Increase or Reduce Calorie Absorption? (01:02) Karen Corbin’s Microbiome Research Journey in Nutrition Science (04:17) New Microbiome Experiments That Could Change How We Eat (11:17) Energy Balance Explained: Calories, Metabolism, and Weight Gain (18:28) How Scientists Study the Gut Microbiome (29:19) Is the Gut Microbiome Causing Obesity and Metabolic Disease? (38:54) How Medications Like Metformin Affect the Gut Microbiome (43:31) Can a High-Fiber Microbiome Diet Reduce Hunger and Cravings? (45:06) Liver Fat, Type 2 Diabetes, and Metabolic Dysfunction Explained (50:44) Best Diet and Nutrition Strategies for Fatty Liver Disease (56:01) How Diet Changes the Gut Microbiome and Metabolism (1:02:27) Probiotics vs Prebiotics: What Actually Improves Gut Health? (1:07:08) GLP-1 Weight Loss Drugs and Their Effects on the Microbiome (1:13:07) Gut Microbiome Metabolites and How They Impact Health (1:16:28) Gut-Brain Connection: How the Microbiome Affects the Brain (1:21:57) Future of Gut Microbiome Research and Personalized Nutrition (1:30:24) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com. | 1h 42m 57s | ||||||
| 1/12/26 |  Protein, increasing bone mineral density, saturated fat and more reflections | Drew Harrisberg | In this episode, Drew Harrisberg and I go deep on life beyond macros and metrics. We talk about gratitude, regret, ageing, and how constant optimisation can quietly pull us away from what actually matters. We also cover living with type 1 diabetes, health tech, social sport, future wellness trends, and why simplicity, connection, and play may be the real foundations of long-term wellbeing. What We Cover Optimisation culture versus presence and joy Regret, legacy, and end-of-life reflections Health data, CGMs, and the mental load of tracking Type 1 diabetes and daily decision fatigue Paddle, play, and the power of social movement Where wellness trends may be heading next A thoughtful, wide-ranging conversation on health, meaning, and living well. To connect with Drew, you can reach him via his Instagram or website, Drew’s Daily Dose, where you can also find his training program. To hear more from Drew, check out his previous episodes on The Proof. Intro (00:00) Dietary Changes and Reflections (03:18) Insulin Sensitivity, Dietary Fat, and Metabolic Health (10:25) Bone Health and Exercise in Older Adults (14:56) Protein Intake, Leucine, and Muscle Protein Synthesis (32:15) Controlled Studies vs. Real-World Results (38:24) How Older Adults Should Optimize Protein Intake (45:13) Ethical and Environmental Trade-Offs of Plant-Based Diets (57:10) Reflecting on Life, Priorities, & Regrets (01:10:15) The Ideal Self vs the “Ought” Self (01:17:27) Struggles with Distraction and Presence (01:24:50) The Future of Longevity Retreats (01:37:44) The Over-Optimization Trap in Health and Life (01:45:08) Why Upcoming Dietary Guidelines May Spark Controversy (01:48:46) Will America’s Obesity Rates Finally Decline? (01:58:30) Music, Creativity, and Personal Challenges (02:04:31) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Momentous My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan. | 2h 16m 17s | ||||||
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