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On the show
Recent episodes
023 - GLP-1 Agonists and Addiction: Surprise!
Mar 18, 2026
23m 07s
022 - A 10 Minute Treatment for Depression : DMT in a Phase 2a Study
Mar 3, 2026
22m 59s
021 - Ethics Roundtable: Prescribing Controlled Substances in a Terminally Ill Patient With Suspected Substance Abuse Disorder and Opioid Agreement Violations
Jan 27, 2026
17m 22s
ACHPN Board Exam Review Part 6: Leadership
Aug 12, 2025
35m 15s
020 - The Surrogate vs the Advance Care Plan
Aug 8, 2025
17m 45s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 3/18/26 |  023 - GLP-1 Agonists and Addiction: Surprise!✨ | GLP-1 AgonistsAddiction+3 | — | GLP-1 receptor agonistssemaglutide+1 | — | GLP-1agonists+6 | — | 23m 07s | |
| 3/3/26 | 022 - A 10 Minute Treatment for Depression : DMT in a Phase 2a Study | Questions? Comments? Send us a message! We discuss a Phase 2a clinical trial investigating the use of intravenous DMT (SPL026) as a fast-acting treatment for major depressive disorder. The research demonstrates that a single dose, paired with psychotherapeutic support, leads to a rapid and significant reduction in symptoms that can last up to three months. Unlike traditional antidepressants that take weeks to work, this short-acting psychedelic provides an immediate effect and was found to b... | 22m 59s | ||||||
| 1/27/26 | 021 - Ethics Roundtable: Prescribing Controlled Substances in a Terminally Ill Patient With Suspected Substance Abuse Disorder and Opioid Agreement Violations | Questions? Comments? Send us a message! This is an interdisciplinary ethics roundtable centered on a terminal lung cancer patient suspected of diverting methadone and violating his controlled substance agreement. Various experts, including physicians, a lawyer, a chaplain, and a psychologist, evaluate the conflict between the duty to relieve suffering and the necessity of maintaining legal and professional boundaries. The contributors suggest strategies ranging from stricter monitoring and l... | 17m 22s | ||||||
| 8/12/25 | ACHPN Board Exam Review Part 6: Leadership | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: The final installment of the prep series focuses on professional issues and leadership. It discusses the "Advocate" role of the ACHPN, quality improvement processes, and staying current with clinical practice guidelines to ensure high-qual... | 35m 15s | ||||||
| 8/8/25 | 020 - The Surrogate vs the Advance Care Plan | Questions? Comments? Send us a message! This episode presents an "Ethics Roundtable" discussion, focusing on the complex case of a 68-year-old female veteran, LK, whose advanced directive conflicts with her family's wishes regarding life-sustaining treatment. The source explores this ethical dilemma from multiple professional viewpoints, including a trauma surgeon, ethicist, spiritual care provider, physician, lawyer, and social worker. Each perspective offers insights into the challenges of... | 17m 45s | ||||||
| 8/8/25 | 019 - DPD Deficiency: To Screen or Not To Screen? | Questions? Comments? Send us a message! This academic article explores the complexities surrounding dihydropyrimidine dehydrogenase (DPD) deficiency screening in patients receiving 5-fluorouracil (5-FU) based chemotherapy. The authors present a case study of a fatal reaction to capecitabine, a prodrug of 5-FU, to illustrate the severe, potentially life-threatening toxicity that can occur in DPD-deficient individuals. The text analyzes various methods of DPD testing, highlighting their limita... | 16m 33s | ||||||
| 8/5/25 | ACHPN Board Exam Review Part 5: Ethics and the Law | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: This episode focuses on the ethical and legal components of palliative care. It reviews key concepts such as advance directives, surrogate decision-making, autonomy, beneficence, and the legal frameworks that govern hospice care in the Uni... | 33m 33s | ||||||
| 8/1/25 | 018 - Is there a role for Cuirass Ventilation (e.g., Iron Lung) in palliative medicine? | Questions? Comments? Send us a message! Cuirass Ventilation: An Alternative Home-Based Modality for Chronic Respiratory Failure" explores biphasic cuirass ventilation (BCV), a portable, non-invasive "forgotten" mode of respiratory support. This article highlights BCV's potential as a comfortable, home-based alternative for patients with chronic respiratory failure, particularly in palliative care settings Onweni C, Rashid S, Goswami R, Treece J, Shipley LC, De Souza R, et al. Cuirass Venti... | 17m 02s | ||||||
| 7/29/25 | ACHPN Board Exam Review Part 4: Psych/Social/Spiritual | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: Part 4 covers the psychological, social, and spiritual aspects of care. The discussion highlights techniques for effective communication, supporting grieving families, and addressing the diverse cultural needs of patients during the end-of... | 20m 37s | ||||||
| 7/22/25 | ACHPN Board Exam Review Part 3: Pain and Symptom Management | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: This session focuses on pain management, a critical component of the board exam. Topics include the assessment of different types of pain, opioid titration, managing side effects, and understanding the "total pain" concept which incorporat... | 34m 45s | ||||||
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| 7/15/25 | ACHPN Board Exam Review Part 2: Clinical Assessment and Physical Symptom Management | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: Part 2 dives into clinical assessment and physical symptom management. The episode breaks down the pathophysiology of common end-of-life symptoms and discusses evidence-based pharmacological and non-pharmacological interventions necessary ... | 24m 34s | ||||||
| 7/8/25 | ACHPN Board Exam Review Part 1: Core Principles | Questions? Comments? Send us a message! The ACHPN Prep (Advanced Certified Hospice and Palliative Nurse) series on the Topics in Palliative Medicine podcast consists of several parts designed to help clinicians prepare for board certification. Description: This introductory episode kicks off the board review series, focusing on the core principles of hospice and palliative nursing. It covers essential domains, including the field's history, the role of the interdisciplinary team, and the fou... | 21m 40s | ||||||
| 6/17/25 | 017 - Suzetrigine - a non-opioid, non-NSAID sodium channel blocker for pain | Questions? Comments? Send us a message! In this episode we discuss suzetrigine, a novel, non-opioid pain medication that specifically targets the NaV1.8 sodium channel to manage acute pain. The document explores its pharmacological mechanisms, highlighting how it blocks pain signals without causing the addictive or severe side effects associated with traditional opioids like respiratory depression or sedation. It reviews preclinical findings and clinical trial results, showcasing suzetr... | 16m 23s | ||||||
| 6/17/25 | 016 - Hypertrophic Pulmonary Osteoarthropathy in Palliative Medicine | Questions? Comments? Send us a message! This episode examines Hypertrophic Pulmonary Osteoarthropathy (HPO), a rare syndrome often associated with underlying pulmonary malignancies. It outlines HPO's clinical presentation, which includes digital clubbing and painful, swollen joints, emphasizing the importance of differentiating it from metastatic bone pain due to its bilateral and symmetrical nature on bone scans. The text further explores the proposed pathophysiological mechanisms, particul... | 19m 29s | ||||||
| 3/10/25 | 015 - Ethics: A Mother in Jeopardy: The Ethics of Pregnancy and Chemotherapy | Questions? Comments? Send us a message! In this episode, we discuss a complex ethical dilemma concerning a pregnant woman diagnosed with advanced ovarian cancer who refuses recommended termination and chemotherapy due to prior fertility struggles. Several experts in medicine, ethics, law, spiritual care, and social work provide differing perspectives on the case. The medical oncology perspective discusses the individualized management of cancer during pregnancy, while the ethics perspective ... | 17m 17s | ||||||
| 2/25/25 | 014 - Symptom Management: Botulinum Toxin for Post Thoracotomy Pain Syndrome | Questions? Comments? Send us a message! This case report explores the use of botulinum toxin type A (BTX-A) injections for treating post-thoracotomy pain syndrome (PTPS), a chronic neuropathic condition affecting many patients after thoracotomy. The study highlights that traditional treatments often fail to provide adequate relief, prompting investigation into alternative therapies. BTX-A's mechanism, which involves reducing inflammation and peripheral neurotransmitters, suggests a potential... | 19m 06s | ||||||
| 2/11/25 | 013 - Symptom Management: Dronabinol for Neuropathic Pain | Questions? Comments? Send us a message! I. Introduction This briefing document synthesizes key findings from several sources exploring the potential of cannabinoids in managing neuropathic pain. The sources include pre-clinical investigations, clinical trial reviews, and decision analysis models, offering a multifaceted view of the topic. We will examine the potential of Cannabidiolic Acid Methyl Ester (CBDA-ME), the effectiveness of cannabis-based medicines, and compare these to traditional... | 18m 22s | ||||||
| 1/28/25 | 012 - Symptom Management: Gabapentin for Intractable Hiccups | Questions? Comments? Send us a message! Hiccups, while often seen as a minor inconvenience, can become a significant health issue when they are persistent or intractable. This episode explores the science behind hiccups, their potential medical causes, and treatment options, particularly the use of gabapentin as an off-label solution. • Discussion of the three types of hiccups: acute, persistent, and intractable • Explanation of the hiccup reflex arc and its neurological basis • Overview of... | 15m 32s | ||||||
| 1/20/25 | 011 - Diagnostics: Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) - An easily missed diagnosis in palliative medicine | Questions? Comments? Send us a message! This case report details a patient with chronic lymphocytic leukemia whose initially misdiagnosed joint pain was ultimately attributed to the rare syndrome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE). The report discusses RS3PE's characteristics, often overlooked due to its rarity and lack of definitive diagnostic criteria, emphasizing the importance of recognizing it in palliative care settings. The paper explores RS3PE'... | 10m 15s | ||||||
| 1/13/25 | 010 - Data: Palliative Medicine Consultation and Hospital Readmissions | Questions? Comments? Send us a message! This retrospective study from a 21-hospital system analyzed the effect of palliative medicine consultations on 30-day hospital readmission rates for patients with six diagnoses (heart failure, sepsis, pneumonia, COPD, AMI, and stroke). The research found statistically significant reductions in readmissions for heart failure, sepsis, and pneumonia patients who received consultations. While reductions were observed in other groups (stroke, AMI, COPD), th... | 12m 03s | ||||||
| 1/9/25 | 009 - Ethics: Life Support after Brain Death | Questions? Comments? Send us a message! This article presents an ethics case study concerning a 52-year-old male declared brain dead, whose family refuses to remove life support. Multiple perspectives—medical, nursing, chaplain, social work, legal, and ethical—are offered, exploring the conflict between the family's emotional denial of death and the medical team's obligation to uphold accepted medical standards. The case highlights the complexities of defining death in the modern era, the im... | 21m 02s | ||||||
| 1/6/25 | 008 - Diagnostics: Post-radiation Lichen Planus | Questions? Comments? Send us a message! This case report details a rare instance of post-radiation lichen planus in a 64-year-old male, following radiation therapy for squamous cell carcinoma. The report examines the patient's medical history, clinical presentation, and treatment response to topical triamcinolone. The authors review existing literature on lichen planus, emphasizing its T-cell mediated inflammatory nature and its rare association with radiation therapy. The study highlights t... | 14m 44s | ||||||
| 1/3/25 | 007 - Diagnostics: Posterior Reversible Encephalopathy Syndrome (PRES) - Don't Miss This Diagnosis! | Questions? Comments? Send us a message! This case report and accompanying discussion detail Posterior Reversible Encephalopathy Syndrome (PRES), a neurological condition presenting with seizures, visual disturbances, and altered mental status. Often misdiagnosed as more severe conditions like intracranial hemorrhage, PRES demonstrates reversible brain swelling on MRI. The case highlights a patient initially suspected of intracerebral hemorrhage whose diagnosis was revised to PRES, leading to... | 13m 49s | ||||||
| 1/2/25 | 006 - Symptom Management: BJR Method for Methadone Conversion | Questions? Comments? Send us a message! The BJR method is a novel mathematical approach to methadone conversion that aims to improve upon existing methods by providing a smoother, less discontinuous, and less linear output for a reasonable and safe methadone dose. Here's how it improves upon existing conversion approaches: Addresses Limitations of the Plonk Method: The Plonk method uses a linear equation to calculate methadone dosage, which assumes a linear relationship between methadone and... | 16m 05s | ||||||
| 12/31/24 | 005 - Cultural: The Therapeutic Baptism : A Case of Missed Cultural Cues in a Terminally Ill Patient | Questions? Comments? Send us a message! The case study underscores the potential for misinterpreting spiritual distress as psychiatric illness, resulting in inappropriate treatment. Clinicians should learn several key lessons from the case of Mr. G, primarily emphasizing the importance of addressing patients' spiritual needs alongside their physical ailments. Open communication: Clinicians should initiate open-ended questions about a patient's spiritual beliefs as part of a routine as... | 27m 27s | ||||||
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