Matt Kaeberlein: 11 aging supplements, reviewed

Matt Kaeberlein: 11 aging supplements, reviewed

From AGING with STRENGTH® by Paul von Zielbauer

November 11, 2025 · 23 min · Season 2 · Episode 2

About this episode

Dr. Matt Kaeberlein discusses aging supplements and the integrity of longevity research.

This is a free preview of a paid episode. To hear more, visit www.agingwithstrength.com Dr. Matt Kaeberlein is a biologist and one of the leading authorities in the space known as longevity medicine. He’s also one of the few leading scientists willing to call out his peers who are, in the vernacular, full of crap . He’s also CEO of health tech company OptiSpan. In this conversation, we discuss Kaeberlein’s dislike of the phrase “longevity medicine,” his willingness to call out longevity chiselers like Harvard’s David Sinclair and why almost all other senior scientists stay silent when their peers lie about or overstate their research. We then go into Kaeberlein’s personal fitness and nutrition routines before ending with his review (for paying subscribers) of 11 popular longevity supplements and a few others that the science shows are most effective. Timestamps 01:32 — Is there any drug, supplement or treatment that can reverse aging in humans? 02:30 — The problem of scientists who mislead the public about longevity research. 04:05 — Exhibit A: David Sinclair, Harvard’s tenured longevity charlatan. “He lied.” 05:38 — Academic scientists who sell supplements through deceptive…

People in this episode

Host: Paul von Zielbauer

Guest: Matt Kaeberlein

Topics covered

  • longevity medicine
  • aging supplements
  • scientific integrity
  • fitness routines
  • nutrition

Keywords

  • aging
  • longevity
  • supplements
  • fitness
  • nutrition
  • scientific integrity
  • biologist

Mentioned in this episode

Organizations: OptiSpan

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