The Brain-Hormone Conversation

The Brain-Hormone Conversation

From Functional Wellness with Dr. Alison by Dr. Alison DiBarto Goggin

May 18, 2026 · 37 min

About this episode

Dr. Alison explores the intricate connections between hormones and brain health, focusing on estrogen, progesterone, and thyroid function.

The Brain-Hormone Conversation Estrogen, Progesterone, Thyroid, the Estrobolome, and the Woman in the Middle of It All If your labs are normal but your brain is anything but, this episode is for you. Dr. Alison goes deep on the hormone-brain connection in Episode 3 of the May brain health series. Estrogen as a brain hormone. Progesterone as the brain’s calming hormone through allopregnanolone and the GABA system. Thyroid as the metabolic gas pedal, and why standard TSH testing misses most of the picture. And the estrobolome, the gut microbiome system that actively recycles and regulates your estrogen from inside your intestines. Includes the labs to actually ask for, why bioidentical progesterone is not the same as synthetic progestins, and why perimenopausal brain symptoms often start years before cycles change. Topics covered: estradiol and neurotransmitters, perimenopausal brain imaging, glucose regulation in the brain, progesterone and allopregnanolone, GABA, bioidentical hormone replacement, full thyroid panels, Hashimoto’s thyroiditis, the estrobolome, beta-glucuronidase, gut-hormone axis, DUTCH testing. The Mama Brain Reset Doors close Sunday May 24 at midnight. The 30-day…

People in this episode

Host: Dr. Alison DiBarto Goggin

Topics covered

  • hormone-brain connection
  • perimenopausal brain health
  • gut-hormone axis
  • bioidentical hormone replacement
  • thyroid health
  • estrobolome

Keywords

  • brain health
  • hormones
  • perimenopause
  • estrobolome
  • bioidentical hormones
  • thyroid testing
  • GABA
  • neurotransmitters

Mentioned in this episode

Organizations: The Mama Brain Reset, Feminine Medicine Class

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