The Estrobolome: Why Your Gut Bacteria Control Your Perimenopause Hormones

About this episode

This episode explores how gut bacteria influence hormone balance during perimenopause, focusing on the estrobolome and its impact on estrogen metabolism.

Struggling with weight gain, hot flashes, mood swings, or brain fog during perimenopause? The answer might be in your gut. In this episode of Functional Wellness with Dr. Alison, we explore the estrobolome—the collection of gut bacteria that directly regulate how your body processes estrogen. Dr. Alison DiBarto Goggin, a functional medicine physician specializing in perimenopause and women's hormones, breaks down the science behind beta-glucuronidase, the enzyme that determines whether estrogen leaves your body or gets recycled back into circulation. You'll learn why you can experience symptoms of estrogen dominance even when blood tests show low estrogen, and what you can do about it. In this 30-minute episode, you'll discover: • What the estrobolome is and how it controls hormone balance during perimenopause • How beta-glucuronidase activity affects estrogen metabolism and drives common symptoms • Why the GI Map stool test is essential for understanding your gut-hormone connection • What disrupts the estrobolome (antibiotics, diet, stress, toxins, inflammation) • Evidence-based strategies to support healthy estrogen metabolism through fiber and probiotics • Specific probiotic…

People in this episode

Hosts: Alison DiBarto Goggin, Alison

Topics covered

• estrobolome
• gut bacteria
• perimenopause
• hormone balance
• beta-glucuronidase
• estrogen metabolism
• GI Map stool test
• probiotics
• liver detox
• fiber

Keywords

• weight gain
• hot flashes
• mood swings
• brain fog
• estrogen dominance
• healthy estrogen metabolism

Mentioned in this episode

Products: RevitaZen, doTERRA PB Restore, doTERRA RevitaZen, doTERRA's PB Restore probiotics

Books & works: Functional Wellness with Dr. Alison

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• Estrogen and Cholesterol · April 29, 2026 · 32 min
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• Perimenopause 101: Why It's Starting Earlier & What You Can Do About It · March 9, 2026 · 19 min