JAMA Clinical Reviews

Nonspecific low back pain is a leading cause of disability, with most cases lacking a clear anatomic cause. This episode reviews risk factors, diagnosis, and current evidence-based treatments for acute and chronic low back pain. JAMA Deputy Editor Mary M. McDermott, MD, interviews author James McAuley, PhD, of the University of New South Wales. Related Content: Low Back Pain What Is Low Back Pain?

Community-acquired pneumonia (CAP) accounts for 1.4 million emergency department visits and 740 000 hospitalizations annually in the US. Author Andre Kumar, MD, MEd, of Stanford University School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the use of point-of-care ultrasound for diagnosis of CAP. Related Content: Point-of-Care Ultrasound for the Diagnosis of Pneumonia Bedside Lung Ultrasound in Emergency (BLUE) for Evaluation of Dyspnea

The GLP-1 receptor agonists reduce appetite and greatly facilitate weight loss. Robert Kushner, MD, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss appropriate diet and exercise recommendations for patients receiving GLP-1 receptor agonists for weight loss. Related Content: Lifestyle Modification and Incretin-Based Therapy for Obesity The Conundrum of Exercise for Weight Management in the GLP-1 Receptor Agonist Era

Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lok, MD, from the University of Michigan discusses HBV transmission, screening, and treatment with JAMA Associate Editor Beverly Forsyth, MD. Related Content: Hepatitis B Hepatitis B Virus Treatment Gaps in the US Tenofovir and Hepatitis B Virus Transmission During Pregnancy US Newborn Hepatitis B Virus Vaccination Rates

In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and ob-gyns Kylie Cooper, MD, and Daniel Breitkopf, MD, both from the Mayo Clinic, discuss ways to reduce maternal morbidity and mortality and improve neonatal outcomes with JAMA Senior Editor Karen Lasser, MD, MPH. Related Content: Prepregnancy Care and Counseling

Explore evidence-based clinical signs, diagnostic accuracy, and practical assessment strategies to optimize care with an in-depth look at the latest information on pediatric concussion. JAMA Review author Sonal N. Shah, MD, MPH, of Boston Children's Hospital, discusses this and more with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Child Have a Concussion? Even Mild Concussions Tied to Worse Cognition Later in Life Vestibular/Ocular Motor Screening (VOMS) in Suspected Concussion Balance and Gait Assessment Including Modified BESS Cervical Spine Examination in Suspected Concussion

Interview with Thomas Ibounig, MD, author of Incidental Rotator Cuff Abnormalities on Magnetic Resonance Imaging and Brian T. Feeley, MD, author of Magnetic Resonance Imaging Abnormalities and Incidental Age-Related Changes. Hosted by Eve Rittenberg, MD. Related Content: Incidental Rotator Cuff Abnormalities on Magnetic Resonance Imaging Magnetic Resonance Imaging Abnormalities and Incidental Age-Related Changes

Peanut allergy affects about 2% of people in the US and most commonly develops in early childhood. Peanut introduction during infancy has led to decreased prevalence of peanut allergy. Author Elissa Abrams, MD, MPH, of the University of Manitoba joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the clinical presentation and methods to diagnose, treat, and decrease the risk of peanut allergy. Related Content: Peanut Allergy

Chronic noninfectious diarrhea affects approximately 6% to 7% of adults in the US and significantly impairs quality of life. Author William Chey, MD, of the University of Michigan joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss strategies for diagnosis and treatment of chronic, noninfectious diarrhea. Related Content: Chronic, Noninfectious Diarrhea

Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the University of Florida joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of type 1 diabetes. Related Content: Type 1 Diabetes

Opioid use disorder is the third most prevalent substance use disorder worldwide. Author Alexander Walley, MB, MSc, of Boston Medical Center and Boston University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the efficacy, safety, and practical considerations of treating patients with medications for opioid use disorder, opioid withdrawal, and opioid overdose. Related Content: Medications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose

IgA nephropathy is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, which often causes kidney failure within 10 to 20 years. Author Michelle Marie O'Shaughnessy, MB, BCh, BAO, MS, of Galway University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, treatment, and prognosis of IgA nephropathy in adults. Related Content: IgA Nephropathy in Adults

Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and politics, with controversy over its legal status and regulation by the US Food and Drug Administration (FDA). Author G. Caleb Alexander, MD, MS, from Johns Hopkins discusses this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS. Related Content: The US Food and Drug Administration's Regulation of Mifepristone Politics, Science, and the Future of FDA Drug Regulation