Too Many Questions

About this episode

Mangesh explores aging through various scientific perspectives, including a suit that simulates being elderly and research on longevity.

Mangesh hops a train to Boston, where he tries on a special suit that turns him into an 80-year-old, discovers the connection between elderly worms and high-end longevity supplements, and meets a scientist who’s growing brains in petri dishes (when she’s not throwing dance parties for mice). Plus: What really happened to Ted Williams’ frozen head? Learn more about AGNES and Joe Coughlin’s work at the MIT AgeLab Learn more about William Mair’s work with the Harvard Healthy Aging Initiative   Read Lenny Guarante’s research on SIR2 and the mechanisms of aging Watch Li-Huei Tsai’s TED Talk about treating Alzheimer’s with light and sound, and learn more about the MIT Aging Brain Initiative   Special thanks to Azadi Records and Bliss Samsa for their beautiful tracks, and Botany for the score.  Episode collage art by Vahini Shori . CORRECTION FOR THIS WEEK: Lenny was contacted by Sequoia, and a then-Sequoia partner is the co-founder and CEO of Elysium, but Sequoia is not an Elysium investor. The company is backed by other venture capital firms. See omnystudio.com/listener for privacy information.

People in this episode

Host: Mangesh

Topics covered

• aging
• longevity
• science
• health
• technology
• research

Keywords

• aging
• longevity supplements
• brain research
• Ted Williams
• Alzheimer's
• MIT
• dance parties
• scientific research

Mentioned in this episode

Organizations: MIT AgeLab, Harvard Healthy Aging Initiative, MIT Aging Brain Initiative, Azadi Records, Bliss Samsa, Botany, Sequoia, Elysium

More episodes of Skyline Drive: How to Live Forever

• Untapped Potential · July 21, 2026 · 60 min
• Organ Trail · July 14, 2026 · 1h 0m
• What Are Blue Zones? · July 7, 2026 · 28 min
• Heal Thyself · June 30, 2026 · 58 min
• Myth Education · June 23, 2026 · 57 min
• The Longevinauts · June 9, 2026 · 51 min