Retatrutide - My Experience

Retatrutide - My Experience

From The Dose with Paddy and Belinda by Green Room Studios

April 22, 2026 · 1h 41m · Season 3 · Episode 17

About this episode

Mimi shares her extraordinary experience in a clinical trial for Retatrutide, detailing her weight loss journey and the challenges faced during the process.

She lost 37% of her body weight. In nine months. On a drug that doesn't officially exist yet in the real world. In this episode, Paddy & Belinda down with Mimi , an Australian nurse and stroke survivor who became one of a handful of people worldwide to trial Retatrutide, Eli Lilly's next-generation triple receptor GLP-1 agonist, as part of a landmark cardiovascular clinical trial. Mimi pulls back the curtain on what it's really like to be inside a pharmaceutical trial, from being forced to dose-escalate to 12mg within months regardless of how her body was responding, to surviving a cold turkey stop after 20 months with zero tapering support. She shares the unfiltered truth about what extreme appetite suppression actually feels like, how she rebuilt her nutrition from scratch when she couldn't keep liquids down, and the moment her DEXA scan revealed how much body fat she actually lost. She also talks about the mental health reality nobody warned her about, the terrifying return of hunger after nearly two years of silence, why her blood pressure medication had to be stopped just four months in, and how she went from qualifying for a trial to now maintaining a nine stone weight on…

People in this episode

Hosts: Paddy, Belinda

Guest: Mimi

Topics covered

  • weight loss
  • pharmaceutical trials
  • mental health
  • appetite suppression
  • cardiovascular health
  • nutrition

Keywords

  • Retatrutide
  • weight loss
  • clinical trial
  • appetite suppression
  • mental health
  • Eli Lilly
  • nutrition
  • cardiovascular health

Mentioned in this episode

Organizations: Eli Lilly, Green Room Studios

Products: Retatrutide, Wegovy

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