The Empowering Neurologist Podcast

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter's newsletter at:⁠ www.drperlmutter.com⁠. ✉️ 🌱EVY - Go to⁠ https://www.optoceutics.com/perlmutter⁠ to get 10% off & free shipping (90 days risk-free).Memory Air - Go to⁠ www.memoryair.com⁠ and use code PERLMUTTER for 15% off, free shipping and a 60-day money back guarantee.====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at ⁠https:/www.braindefenders.com⁠.====Your food contains far more than protein, carbohydrates, fat, vitamins, and minerals. Researchers have identified more than 100,000 molecules in food, and most of them never appear on a nutrition label.In this episode of The Empowering Neurologist, Dr. David Perlmutter sits down with his son, Dr. Austin Perlmutter, to explore the "dark matter" of nutrition: thousands of plant compounds called polyphenols.They discuss how these nutrients may influence the gut microbiome, the immune system, inflammation, blood flow, metabolism, and gene expression, and what high-polyphenol diets may mean for memory and the aging brain.Dr. Austin also shares his research on Himalayan Tartary buckwheat and what an early study suggests about epigenetics, cognition, and healthy aging. He offers practical ways to find more polyphenols in everyday foods like coffee, tea, dark chocolate, berries, legumes, and extra virgin olive oil, plus simple tips for identifying better options at the grocery store.You don't need an expensive supplement plan to begin. Adding more natural colors and bitter flavors to your plate can be a meaningful first step.https://bttcorp.com/contact/ for inquiries about Dr. Abreu's work.00:00 — Cold Open: Why Food Matters for Brain Health00:55 — What Are Polyphenols, and Why Do They Matter?02:15 — Food as a Predictor of Long-Term Brain Health04:23 — The “Dark Matter” Hidden in Our Food08:04 — Why Have These Nutrients Been Overlooked?11:06 — What Polyphenols Actually Do in the Body17:32 — How Food Can Change Gene Expression22:08 — Polyphenols Are More Than Antioxidants27:57 — Himalayan Tartary Buckwheat: Putting “Food as Medicine” to the Test32:16 — The 850-Person Study on Food and Cognition36:14 — Where Are We Getting Our Polyphenols?39:19 — Are Polyphenols Actually Beneficial Stressors?41:58 — Nrf2, mTOR, and the Cellular Effects of Polyphenols44:45 — The Practical Takeaway: Eat the Rainbow46:43 — Do the New Dietary Guidelines Get Polyphenols Right?50:25 — The Hidden Brain-Healthy Ingredient in Coffee50:52 — How to Spot a Polyphenol-Rich Olive Oil51:39 — Dark Chocolate vs. Milk Chocolate52:59 — The Best-Studied “Longevity Strategy” Is Surprisingly Basic====Dr. Austin Perlmutter, MD, is a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, and entrepreneur. He earned his medical degree from the University of Miami Miller School of Medicine and completed his internal medicine residency at Oregon Health and Science University. His work examines how food, sleep, environmental exposure, and chronic inflammation can change brain function, mental health, and daily choices. He is the co-author of the New York Times bestseller Brain Wash, written with his father, Dr. David Perlmutter. He serves as Managing Director at Big Bold Health, CEO of Lichen Air, and a research consultant at the Helfgott Research Institute.Website: https://www.austinperlmutter.com Instagram: https://www.instagram.com/draustinperlmutterFacebook: https://www.facebook.com/draustinperlmutterYouTube: https://www.youtube.com/channel/UCQOgwRDnA_vpvW9nnUh9KBgInstagram: /davidperlmutterWebsite: https://www.drperlmutter.com/Subscribe to our channel: /@davidperlmuttermdThis podcast is produced by DrTalks.com⁠http://drtalks.com/channel-growth

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Thank you to our sponsors:EVY - Go to https://www.optoceutics.com/perlmutter to get 10% off & free shipping (90 days risk-free).Memory Air - Go to www.memoryair.com and use code PERLMUTTER for 15% off, free shipping and a 60-day money back guarantee.====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at https:/www.braindefenders.com.====Recent headlines surrounding a reported case of ALS reversal have captured global attention and raised profound questions about what may be possible in the treatment of neurodegenerative disease.In this episode of The Empowering Neurologist, Dr. David Perlmutter examines the work of Dr. M. Marc Abreu, founder and chief medical officer of the BTT Medical Institute. Trained in medicine, biomedical engineering, and medical physics, Dr. Abreu’s work sits at the intersection of neurology, thermodynamics, and computational biology. During his time at Yale, he identified the brain thermoregulatory tunnel, an insight that helped lay the foundation for his current research into brain temperature and neurological disease.Dr. Abreu’s recently published case report describes a patient with documented, progressive ALS who reportedly experienced a dramatic clinical and electrophysiological reversal following a novel, AI-guided, brain-directed thermofebrile intervention.The implications are extraordinary, but so is the need for careful scientific scrutiny. A single case report cannot establish that a treatment is effective, much less prove a cure. What it can do is raise important questions and potentially point researchers toward biological mechanisms worthy of further investigation.00:00 — Can ALS Really Be Reversed?02:32 — A Bold Claim: Treating ALS With Brain Hyperthermia03:42 — Dr. Marc Abreu’s Remarkable Medical Journey10:00 — The Brain’s Language Is Thermodynamics11:54 — The 100-Year-Old Treatment That Inspired a New Approach13:36 — TDP-43 and the Molecular Signature of ALS15:46 — Why the Fever Cycle May Be the Key16:41 — How Brain Temperature Technology Was Developed20:04 — The ALS Patient Who Underwent the Treatment20:57 — Kent’s ALS Diagnosis and Rapid Decline24:31 — 12 Hyperthermia Treatments: What Happened?26:00 — Measuring the Results: Did His Symptoms Improve?28:32 — A Neurologist Witnesses Kent’s Recovery29:49 — How Kent Found Dr. Abreu’s Treatment32:42 — A Mayo Clinic ALS Case and the Evidence37:48 — Could ALS Ever Resolve Spontaneously?39:39 — Are Other ALS Patients Seeing Similar Results?40:13 — Why Is Mainstream Neurology Skeptical?43:51 — Kent on Living With an ALS “Death Sentence”46:56 — From Struggling to Functioning Again47:37 — What Would It Take to Change Neurology?49:57 — How to Learn More About the Treatment51:27 — The Mosquito, Malaria, and the Brain52:26 — Could This Have Implications Beyond ALS?54:22 — What This Could Mean for the Future of Neurodegeneration56:31 — EndDr. M. Marc Abreu is a physician and physicist specializing in brain thermodynamics, thermoregulation, and neurological health. He is the Medical Director of the BTT Medical Institute and is internationally recognized for his discovery of the Brain Thermal Tunnel (BTT), a thermophysical pathway connecting the eyelids to the hypothalamus.Instagram: davidperlmutterWebsite: https://www.drperlmutter.com/Subscribe to our channel: @davidperlmuttermd