132: I Tested a Fasting Supplement for a Year — Here's What It Did to My Biological Age | Chris Rhodes, CEO of Mimio Health
From The Primal Shift by Michael Kummer
March 25, 2026 · 59 min · Season 2 · Episode 132
About this episode
Dr. Chris Rhodes discusses the benefits of fasting and the impact of the Mimio supplement on biological age.
Your body already knows how to live to 120 in perfect health. It's just not doing it. That realization is what sent Dr. Chris Rhodes down the fasting research path during his PhD in nutritional biochemistry at UC Davis. His argument? Most people doing 16:8 intermittent fasting aren't getting nearly the benefits they think they are. The body doesn't flip into fasting mode until glycogen stores are depleted, which typically takes 20 to 24 hours. Autophagy, stem cell regeneration, and the real anti-inflammatory benefits don't peak until around 72 hours. In this episode, Dr. Rhodes, creator of Mimio – the world's first fasting mimetic supplement – explains what his team discovered when they tracked metabolites during 36-hour fasts in healthy subjects, as well as how they isolated four synergistic molecules that recreate fasting benefits at the cellular level. We also dig into something personal. Almost a year ago, I started supplementing with Mimio and tracked my biological age using TrueAge epigenetic testing before, during, and after. The result? My pace of aging slowed to 0.85 – meaning that for every calendar year, I'm only aging about 10 months biologically. Rhodes walks me…
People in this episode
Host: Michael Kummer
Guest: Chris Rhodes
Topics covered
- fasting
- biological age
- nutritional biochemistry
- health benefits
- epigenetic testing
Keywords
- fasting
- biological age
- Mimio
- epigenetic testing
- nutritional biochemistry
Mentioned in this episode
Organizations: Mimio Health, UC Davis
Products: Mimio
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