
The episode discusses the role of carbohydrates in endurance performance and challenges the notion that fatigue is solely due to glycogen depletion.
A thoughtful response to the recent Noakes et al. review questioning the role of carbohydrates in endurance performance. We explore why fatigue isn’t caused by running out of muscle glycogen, why blood glucose protection is critical, and why that still doesn’t explain elite fueling strategies. Using recent research and real-world endurance racing, we explain how carbohydrate availability supports mitochondrial throughput, late-race durability, and sustained power — even when glycogen isn’t spared.
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