The School of Greatness

Dr. Gabrielle Lyon, fellowship-trained geriatrician and founder of muscle-centric medicine, mentored for two decades by protein researcher Dr. Donald Layman of the University of Illinois, explains why skeletal muscle, not body fat, governs glucose disposal, metabolic health, and longevity. Covers the leucine meal threshold, anabolic resistance, sarcopenia, myokines including interleukin-6 and BDNF, the WWII nitrogen-balance origins of the 0.8g/kg protein RDA, and the GRADE-system red meat analysis published in Annals of Internal Medicine.

Dr. Lisa Miller, Columbia University professor and author of The Spiritual Child: The New Science of Parenting for Health and Lifelong Thriving, draws on 10 years of MRI research and a global study of 270,000 children to explain the three circuits of the awakened brain (bonding network, ventral attention network, parietal network). Covers the 4 P's framework (Practice, People, Purpose, Path), achieving vs. awakened relationships, spiritual injury, post-traumatic spiritual growth, and findings showing a strong spiritual life is 80% protective against addiction onset and 82% protective against completed teen suicide.

George Kamel, #1 national bestselling author of Breaking Free from Broke and co-host of The Ramsey Show, reveals the Baby Steps framework, debt snowball method, and SMART Spender framework (Self-awareness, Motive, Affordability, Research, Timing). Covers financial infidelity, lifestyle creep, the doom loop of emotional spending (Dr. Arthur Brooks), buy now pay later dangers (Klarna, 40% cart size increase), prediction markets, the Goldman Sachs finding that 40% of $500K+ earners live paycheck to paycheck, and Ramsey Solutions EveryDollar app.

Emmanuel Acho, former NFL linebacker, Fox Sports television host, bestselling author of Illogical: Saying Yes to a Life Without Limits, and the only person outside of Oprah to publish multiple books under the Oprah Winfrey imprint, joins Lewis Howes to discuss reframing failure, releasing goal-setting in favor of objectives, navigating public criticism, building self-love through success, and the mindset shifts required to break through limits others cannot yet see.

David Epstein, investigative journalist, science writer, and bestselling author of Range and Inside the Box: How Constraints Make Us Better, joins Lewis Howes to explore how strategic constraints unlock creativity, focus, and performance. The conversation covers the BCS Press Release framework, kind vs. wicked learning environments, the 10,000-hour rule myth, the Harvard Study of Adult Development, satisficing rules, the subtractive neglect bias, and research from MIT, Northwestern, and the Census Bureau on founder age and startup success.

Dr. Michael J. Breus, board-certified sleep specialist, clinical psychologist, and bestselling author, shares his five-step framework for transforming sleep quality through circadian rhythm alignment and chronotype optimization. Topics include adenosine and sleep drive, the 4-7-8 breathing technique developed by Dr. Andrew Weil, the Napa Latte protocol, non-sleep deep rest (Yoga Nidra), melatonin misconceptions, the Time Shifter jet lag app, thermoregulatory sleep pads, chrono longevity, PTSD and nightmare therapy, and how timing of caffeine, exercise, and alcohol impacts restorative sleep.

Dr. Mindy Pelz, fasting expert, functional health practitioner, and bestselling author of Fast Like a Girl, joins Lewis Howes to discuss intermittent fasting, the hormonal hierarchy, the menstrual fasting cycle, ketogenic energy systems, cortisol, oxytocin, the effects of birth control on the gut microbiome, the Power Sync 60 fitness program, and how fasting timing affects fat loss, libido, and hormone balance for both men and women.

Three-time New York Times bestselling author and high performance coach Brendon Burchard joins Lewis Howes to introduce his FREE framework (Feeling, Responsibility, Expression, Expansion) and the "complexity ceiling" concept from High Performance Habits. They cover imposter syndrome after success, generating internal state on purpose, and building a dialogue with your future self.

Anita Moorjani spent decades living in fear of cancer, people-pleasing her way through life, and shrinking herself to fit others' expectations - until the disease she feared most put her in a coma with organs shutting down. You'll discover why the real illness was never the cancer, and how facing death finally taught her to love herself enough to come back and live.

At 95, Dr. Edith Eger -- a Holocaust survivor, psychologist, and bestselling author -- sits down just days after losing her sister to share the lessons that carried her from the gas chambers of Auschwitz to a life overflowing with joy, meaning, and freedom. You will walk away knowing the one shift that separates people who heal from those who stay trapped forever.

Ryan Leak has spent his career pulling people's lives off the floor, and in this conversation, he gets radically honest about what it actually takes to deal with difficult people, set boundaries on your friendships, and trust something bigger than yourself when others let you down. You will walk away with a framework for handling the hardest relationships in your life without losing who you are in the process.

At 19, Amy Purdy lost both legs, a kidney, her spleen, and the hearing in her left ear overnight, and she made a choice in that operating room that changed everything. This conversation will show you how to stop seeing your hardest moments as detours and start using them as the path to a life you never could have planned.

Michael Pollan, the bestselling author who changed how we think about food, reveals why the healthiest-sounding foods on your grocery shelf are actually making you sick. You'll discover the simple seven-word mantra that transforms your relationship with eating and finally breaks free from processed food cravings.