
Feeling Stuck on Antidepressants in Midlife? How to Taper Off Safely with Mark Horowitz, PhD
From BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause by Dr. Stephanie Estima, Perimenopause & Women's Fitness Expert
March 23, 2026 · 1h 26m
About this episode
Dr. Mark Horowitz discusses the long-term effects of antidepressants and how to taper off safely.
56 million Americans are on antidepressants — and 25 million have been for more than five years. Psychiatry researcher and de-prescribing expert Dr. Mark Horowitz unpacks what antidepressants are actually doing to your brain and body over the long term, including effects on mood, weight, sleep, memory, and sexual function. Watch the full episode at https://youtu.be/30Y9eMEqltA
People in this episode
Host: Dr. Stephanie Estima
Guest: Mark Horowitz
Topics covered
- antidepressants
- mental health
- de-prescribing
- midlife
- psychiatry
- brain health
Keywords
- antidepressants
- tapering off
- mental health
- midlife
- de-prescribing
- psychiatry
- brain
- mood
- sleep
- memory
Mentioned in this episode
Organizations: YouTube
More episodes of BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause
- How Nitric Oxide Controls Blood Flow, Energy & Hormone Function with Cathy Eason, MS, BCHN · September 7, 2026 · 1h 17m
- Your Brain on AI: How to Build Your Memory Muscle Before You Borrow It with Jim Kwik · August 31, 2026 · 56 min
- Pilates Girls, You're Losing Bone. The Exercise Science of Building Bone After 40 with Prof Belinda Beck · August 24, 2026 · 1h 14m
- Frozen Shoulder, Aching Hips & Just Aging: Midlife Joint Pain with Dr. Tom Walters · August 17, 2026 · 1h 25m
- Spiritual Fitness: Letting Go vs. Giving Up with Danielle LaPorte · August 10, 2026 · 1h 22m
- Why Your Body Composition Isn't Changing (And It's Not What You Think) · August 3, 2026 · 42 min
Explore listener stats, chart rankings, contacts and more on the BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause podcast page.