
Feeling Stuck on Antidepressants in Midlife? How to Taper Off Safely with Mark Horowitz, PhD
From BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause by Dr. Stephanie Estima, Perimenopause & Women's Fitness Expert
March 23, 2026 · 1h 26m
About this episode
Dr. Mark Horowitz discusses the long-term effects of antidepressants and how to taper off safely.
56 million Americans are on antidepressants — and 25 million have been for more than five years. Psychiatry researcher and de-prescribing expert Dr. Mark Horowitz unpacks what antidepressants are actually doing to your brain and body over the long term, including effects on mood, weight, sleep, memory, and sexual function. Watch the full episode at https://youtu.be/30Y9eMEqltA
People in this episode
Host: Dr. Stephanie Estima
Guest: Mark Horowitz
Topics covered
- antidepressants
- mental health
- de-prescribing
- midlife
- psychiatry
- brain health
Keywords
- antidepressants
- tapering off
- mental health
- midlife
- de-prescribing
- psychiatry
- brain
- mood
- sleep
- memory
Mentioned in this episode
Organizations: YouTube
More episodes of BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause
- Is Muscle Soreness Progress? Dial in Your Exercise Intensity & Recovery with Dani Coleman · July 20, 2026 · 53 min
- Don't Love the Stairmaster: Try Passive Cardio with Infrared Sauna with Connie Zack · July 13, 2026 · 1h 8m
- Look. Feel. Perform. Why Muscle Is the Answer to All Three After 40 with Andy Galpin, PhD · July 6, 2026 · 1h 7m
- HRT Can’t Fix Your Ligaments: The Diabolical Role of Estrogen on Connective Tissue · June 29, 2026 · 52 min
- Stop Trying to Feel Better — Get Better at Feeling: Heal Anxiety from the Body Up with Dr. Russell Kennedy · June 22, 2026 · 1h 21m
- More Cardio, Less Food, Still Gaining: Your Midlife Fitness Do-over with Natalie Jill · June 15, 2026 · 1h 8m
Explore listener stats, chart rankings, contacts and more on the BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause podcast page.