The Truth About GLP-1 Weight Loss and Muscle Loss | Ep. 358

About this episode

Nikkiey discusses the effects of GLP-1 medications on weight loss and the risk of muscle loss.

In this episode of The Macro Hour, Nikkiey breaks down the truth about GLP-1 medications and their impact on body composition—especially the often-overlooked risk of muscle loss. While these medications can be effective for weight loss, Nikkiey explains why the number on the scale doesn’t tell the full story. Losing muscle can slow your metabolism, impact long-term results, and make weight regain more likely—especially for women in midlife. She also shares the non-negotiables for protecting y...

People in this episode

Host: Nikkiey Stott

Topics covered

• GLP-1 medications
• weight loss
• muscle loss
• body composition
• metabolism
• women's health

Keywords

• GLP-1
• weight loss
• muscle loss
• body composition
• metabolism
• women in midlife

Mentioned in this episode

Products: GLP-1 medications

Places: midlife

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• Why Women Over 40 Keep Restarting Their Fat Loss Every January (And How To Stop It) | Ep. 393 · September 4, 2026 · 28 min
• Switching Programs Is Why You're Not Building Muscle After 40 | Ep. 392 · August 31, 2026 · 22 min
• The #1 Excuse Keeping Women Over 40 Out of Shape | Ep. 391 · August 28, 2026 · 26 min
• Eating Less Is Why You're Not Losing Fat After 40 (Here's Why) | Ep. 390 · August 24, 2026 · 30 min