Modern Thyroid and Wellness

What if insulin resistance is quietly driving inflammation, weight gain, and thyroid dysfunction years before blood sugar ever looks abnormal?In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with endocrinologist Dr. Alessia Roehnelt for an in-depth conversation about insulin resistance and why it can be such an important marker of long-term metabolic health.Dr. Roehnelt explains how insulin functions in the body, what happens when insulin resistance develops, and why chronically elevated insulin can contribute to inflammation, weight gain, metabolic dysfunction, and disease progression.They also explore the bidirectional relationship between insulin resistance and hypothyroidism, including how thyroid dysfunction can worsen metabolic health and how insulin resistance can complicate thyroid function and treatment.🔑 In This Episode:What insulin resistance is and how it developsWhy insulin resistance may appear before prediabetes or type 2 diabetesCommon physical and metabolic signs of insulin resistanceAcanthosis nigricans, carb sensitivity, and rapid weight fluctuationsThe relationship between insulin resistance and hypothyroidismHow insulin resistance may affect thyroid hormone absorption and conversionWhy fasting insulin can provide useful information beyond A1c alone“Normal” vs. optimal fasting glucose, insulin, and A1c valuesWhy population-based lab ranges do not always reflect optimal healthThe role of vitamin D in metabolic and hormonal healthFatty liver markers including AST and ALT🏃‍♀️ Improving Insulin SensitivityDr. Roehnelt and McCall discuss foundational strategies including:Consistent, restorative sleepStrength and resistance trainingReducing refined carbohydratesPairing carbohydrates with protein and fatUsing continuous glucose monitors to better understand personal responsesStrategic intermittent fasting when appropriate💊 Medications DiscussedMetforminImproves insulin sensitivityHas a long history of clinical useCan be a cost-effective early interventionGLP-1 receptor agonistsReduce appetite and slow gastric emptyingLower liver glucose productionImprove insulin signalingMay help reduce inflammation in appropriate patients🌿 Key TakeawaysInsulin resistance can often be improved when identified early.“Normal” lab values do not always tell the entire story, and weight gain is far more complex than calories in versus calories out.One of the biggest themes in this episode is that inflammation connects metabolic dysfunction, thyroid disease, and autoimmunity, making individualized, whole-body evaluation incredibly important. 📖 Pre-Order Take Back Your Thyroid + Get a Free BonusPre-order McCall McPherson’s new book, Take Back Your Thyroid, and choose one free bonus:🎓 Thyroid Empowered Course — a $399 valueOR🩺 $150 off a new patient visit at Modern Thyroid Clinic👉 https://book.modernthyroidclinic.com/📍 Connect with Dr. Alessia RoehneltWebsite & Practice:https://www.endohealthdoc.comInstagram:https://www.instagram.com/endohealthdoc/Facebook:https://www.facebook.com/alessia.roehnelt📲 Follow McCall McPherson & Modern Thyroid and WellnessModern Thyroid Clinic:https://modernthyroidclinic.com/McCall McPherson:https://www.mccallmcpherson.com/Instagram:https://www.instagram.com/mccallmcphersonpa/YouTube:https://www.youtube.com/channel/UC0_JyQdBAJwYT3rMDsvyriwFacebook:https://www.facebook.com/McCallMcPhersonPAC/X / Twitter:https://x.com/thyroidexpert

What happens when you’re doing everything “right” for your health but still don’t feel like yourself?In this episode of Modern Thyroid & Wellness, McCall McPherson sits down with Nicole Peterson Doran, co-founder of PUR-FORM, Humanaut Health franchisee, and host of The Healthspan Collective Podcast, to talk about her decades-long journey through PCOS, hypothyroidism, inflammation, fertility concerns, long COVID, mast cell activation symptoms, and ultimately finding a more personalized approach to health.Nicole’s story began at just 16 years old when she rapidly gained weight, developed facial hair, experienced irregular periods, severe fatigue, and intense brain fog. She was diagnosed with PCOS and later hypothyroidism, but traditional treatment did little to resolve how she actually felt.That experience eventually led her into integrative medicine, whole-food nutrition, mindfulness, and the concept of bio-individuality—the idea that what works for one person may not work for another.In This Episode:Nicole’s experience with PCOS and hypothyroidism beginning in her teensWhy whole foods and lifestyle changes became a turning pointThe importance of bio-individuality in thyroid and hormone healthWhy there is no single “best” diet, medication, or wellness plan for everyoneHow Nicole prepared her body for pregnancy after years of PCOSThe supplements and lifestyle changes she personally used while preparing for fertilityHer long-COVID journey and mast cell activation symptomsHer personal experience with microdosed tirzepatideThymosin alpha-1 and larazotideWhy gut health became an important piece of her recoveryWhat EBO2 is and how PUR-FORM uses regenerative therapiesThe evolution from struggling patient to health entrepreneurFertility After PCOSNicole shares how being told as a teenager that getting pregnant could be difficult stayed with her for years.When she decided she wanted to conceive, she worked intentionally with her practitioners, focused on reducing inflammation, prioritized rest, limited travel, reduced alcohol and sugar, and used supplements including CoQ10 and fish oil.She became pregnant after approximately three months, while emphasizing that fertility is deeply individual and there is still an element of uncertainty that cannot always be controlled.Long COVID, MCAS & Finding New ToolsAfter COVID, Nicole experienced months of intense histamine-type symptoms, inflammation, brain fog, irritability, and weight changes.She describes working with practitioners and personally using several tools during her recovery, including microdosed tirzepatide, thymosin alpha-1, larazotide, nutritional support, and regenerative therapies. These are shared as Nicole’s personal experience and are not recommendations for every listener.About Nicole Peterson DoranNicole Peterson Doran is a co-founder of PUR-FORM, a comprehensive health optimization clinic in Boca Raton, Florida. She is also involved with Humanaut Health and hosts The Healthspan Collective Podcast.Her work focuses on personalized health, metabolic and hormonal wellness, regenerative medicine, and helping people find answers when conventional approaches have not been enough.Connect with NicoleInstagram:https://www.instagram.com/nicolejdoran/LinkedIn:https://www.linkedin.com/in/nicolejpeterson/PUR-FORM:https://purformhealth.com/Humanaut Health:https://humanauthealth.com/This episode is for educational purposes only and does not replace individualized medical advice.📖 Pre-Order Take Back Your Thyroid + Get a Free BonusPre-order McCall McPherson’s new book, Take Back Your Thyroid, and choose one free bonus:🎓 Thyroid Empowered Course, a $399 valueOR🩺 $150 off a new patient visit at Modern Thyroid ClinicPre-Order & Claim Your Free Bonus📲 Follow McCall McPherson & Modern Thyroid and Wellness💻 Website: modernthyroidclinic.com🐦 X / Twitter: @thyroidexpert🌐 Host Website: mccallmcpherson.com📺 YouTube: McCall McPherson Channel📘 Facebook: McCall McPherson PAC📸 Instagram: @mccallmcphersonpa

Could a simple neck self-check help you notice a thyroid concern earlier?September is Thyroid Cancer Awareness Month, and in this episode of Modern Thyroid & Wellness, McCall McPherson sits down with Dr. Rashmi Roy, a fellowship-trained, board-certified endocrine surgeon specializing in thyroid and parathyroid disorders.Dr. Roy practices at the Hospital for Endocrine Surgery in Tampa and has performed thousands of thyroid and parathyroid procedures. Together, McCall and Dr. Roy have an important conversation about thyroid cancer risk, early detection, diagnosis, thyroid nodules, surgery, Hashimoto’s, and how patients can make more informed decisions about their thyroid health.They discuss how to perform a neck self-check, potential signs and risk factors to be aware of, and when thyroid ultrasound or additional evaluation may be appropriate.Dr. Roy also explains what patients should know before thyroid surgery, including common misconceptions, potential complications, and why the experience of your thyroid surgeon can matter when evaluating surgical options.The conversation also explores Hashimoto’s thyroiditis, its relationship to overall thyroid health and thyroid cancer risk, evolving approaches to treatment and post-surgical management, and why learning to ask better questions can help you become a stronger advocate for your own care.Whether you are navigating a thyroid nodule, Hashimoto’s, a possible thyroid cancer diagnosis, or an upcoming thyroid surgery, this episode offers practical information to help you approach the next step with greater clarity.🔑 In This Episode:How to perform a neck self-checkSigns, symptoms, and risk factors associated with thyroid cancerWhen thyroid ultrasound or additional screening may be consideredWhat patients should know about thyroid nodulesWhy surgeon experience matters when choosing a thyroid surgeonCommon myths about thyroid surgeryPotential risks and complications of thyroid surgeryHashimoto’s and its relationship to thyroid health and thyroid cancer riskNew and emerging approaches to treatment and post-surgical managementHow to advocate for yourself and ask better questions about your care👩‍⚕️ About Dr. Rashmi RoyDr. Rashmi Roy is a fellowship-trained, board-certified endocrine surgeon specializing in thyroid and parathyroid disorders. She practices at the Hospital for Endocrine Surgery in Tampa and has performed thousands of thyroid and parathyroid procedures.Her extensive surgical experience gives her a valuable perspective on thyroid cancer diagnosis, surgical decision-making, potential complications, and what patients should consider when selecting a thyroid surgeon.If you know someone navigating thyroid nodules, thyroid cancer, Hashimoto’s, or an upcoming thyroid surgery, share this episode with them during Thyroid Cancer Awareness Month.📘 Pre-Order Take Back Your ThyroidMcCall McPherson’s new book, Take Back Your Thyroid, is available for pre-order now.Pre-order and receive FREE access to the Thyroid Empowered Course — a $399 value.👉 Pre-order here:https://book.modernthyroidclinic.com/📲 Connect with McCall & Modern Thyroid ClinicMcCall McPherson, PA-CInstagram: @mccallmcphersonpa https://www.instagram.com/mccallmcphersonpa/Modern Thyroid ClinicInstagram: @modernthyroid https://www.instagram.com/modernthyroid/Learn more about Modern Thyroid Clinic:https://www.modernthyroidclinic.com/This content is for educational purposes only and is not intended to diagnose, treat, or replace individualized medical care.#ThyroidCancerAwarenessMonth #ThyroidCancer #ThyroidHealth #ThyroidCancerAwareness #ThyroidSurgery #ThyroidNodules #Hashimotos #HashimotosDisease #Hypothyroidism #ThyroidDisease #EndocrineHealth #WomensHealth #ModernThyroidClinic #McCallMcPherson #TakeBackYourThyroid