The Energy Blueprint Podcast

In this episode, I am speaking with Dr. Eric Gordon, MD, who has spent the last 40 years helping his patients overcome chronic complex illnesses by focusing on mitochondria and cellular communication. We will discuss the Cell Danger Response, mitochondria, lifestyle, and much, much more.

What if some people diagnosed with chronic fatigue, fibromyalgia, autoimmune disease, anxiety, or even early Alzheimer's are actually dealing with an underlying infection that was never properly identified? Today, I'm sharing my conversation with Dr. Richard Horowitz, a board-certified internist who has treated more than 13,000 patients with Lyme and tick-borne disease over the last four decades, many of whom had already seen countless doctors and collected diagnoses like chronic fatigue syndrome, fibromyalgia, depression, anxiety, multiple sclerosis, and early dementia before discovering Lyme may have been part of the picture. Dr. Horowitz calls Lyme "the great imitator" because its symptoms can overlap with so many other conditions, and since 2016, Dr. Horowitz has published 11 papers on treatment approaches. In one of his latest studies, he and his colleagues explored a possible connection between Lyme disease and Alzheimer's biomarkers, reporting major improvements in certain inflammatory and cognitive-related markers after treatment. We discuss his broader "MSIDS" model, which looks at chronic illness through a much wider lens. Instead of looking for one single cause, the model examines multiple overlapping factors that may contribute to illness, including infections, toxins, gut dysfunction, nutrient deficiencies, sleep issues, immune imbalance, and inflammation. In this podcast, Dr. Horowitz and I discuss: Why Lyme disease is called "the great imitator" and how it can resemble chronic fatigue syndrome, fibromyalgia, multiple sclerosis, anxiety, depression, and Alzheimer's disease The often-overlooked migratory pain that is one of the hallmark symptoms of chronic Lyme The Lyme symptom questionnaire, which he developed and validated on 6,400 patients How research from Johns Hopkins and other universities changed our understanding of Lyme as a persistent infection Why Dr. Horowitz began using drugs like dapsone and rifampin in Lyme treatment protocols His published research on dapsone combination therapy and the improvements he has observed in patients His recent findings on Lyme disease and Alzheimer's biomarkers, including reductions in tau217 levels Dr. Horowitz's unique MSIDS model and the many overlapping factors that may drive chronic illness Why chronic illness rates continue rising and what conventional medicine may still be missing Why Dr. Horowitz believes recovery is possible, even for patients who have been sick for years

Most people think fatigue is simple. You're tired because you didn't sleep enough. Or you're stressed. Or maybe you just need more caffeine. But what if you've addressed all those factors and are still fatigued? Today, I'm joined by Dr. Evan Hirsch, a physician who has helped thousands of people recover from chronic fatigue after experiencing it himself. And according to Dr. Hirsch, fatigue is rarely caused by one singular thing. When you look deeper, a pattern emerges. Hidden infections, environmental toxins, nutrient deficiencies, poor sleep quality, and nervous system dysfunction often show up together. Once you start connecting these dots, fatigue stops looking like a simple problem and starts looking like a signal. In this episode, Dr. Hirsch and I break down the real drivers of low energy and what it actually takes to fix them, not just manage symptoms. This episode was first released in June 2017 In this podcast, Dr. Hirsch and I discuss: Why fatigue is often driven by multiple root causes, not just lack of sleep, stress, or an isolated virus How toxins, mold, and environmental exposures can silently drain your energy, and why they need to be addressed slowly versus "hard and heavy" Why poor sleep quality, not just sleep duration, is often the real issue Why many people wake up at night (and what it really means) How hidden infections, yeast, or even parasites may contribute to fatigue and long-term brain health Why morning habits can improve sleep and energy more than nighttime routines The three supplements Dr. Hirsch leans on the most when working with chronic fatigue patients How addressing root causes can lead to lasting improvements in energy

My guest today, Dr. Wendie Trubow, went to France in 2019 for the trip of a lifetime. But when she came home, her hair started falling out, she gained weight, and had a rash all over her face. She tested her thyroid (perfect), hormones (perfect), and gut (great). Ultimately, she realized that when Notre Dame burned, it released 500 tons of lead into the air and soil, and she had slogged through that dust for a week. Testing showed that her lead levels were incredibly high. Her biggest insight was that all the modern medical issues she treated as a functional MD—obesity, diabetes, cancer, insomnia, endocrine dysfunction, gut dysfunction—could be tracked back to toxic exposures, creating a state of inflammation. Dr. Trubow believes your particular "soup" (genetics, lifestyle, early childhood, antibiotic use, diet, sleep, stress, relationships, self-talk, movement) determines how inflammation manifests in you. Wendie's story is really incredible, and I think you'll love this podcast. This episode was first released in Jan 2023 In this podcast, Dr. Trubow and I discuss: How toxins are related to stubborn weight: they get stored in fatty tissue when you exceed your body's ability to excrete them Studies show that levels of persistent organic pollutants ("forever chemicals") in the bloodstream during weight loss predict weight regain! Alcohol is an acute toxin that takes priority in the liver—your body stops all other detox behavior (hormone processing, pesticide excretion) to focus exclusively on processing alcohol By the time most women leave the house, they've put over 200 chemicals on their bodies, from shampoo, conditioner, face products, makeup, moisturizers, and perfumes Your bed is a hidden toxin if it contains flame retardants—these are endocrine disruptors, mess up your thyroid and female hormones, and raise your risk of estrogen-dependent cancers Never ask "What-if?" questions…ruminating about uncontrollable situations sends your body into fight-flight-freeze and shuts down detox New cars contain over 300 chemicals, and even new clothes are sprayed with chemicals—wash clothes before you wear them, and shop consciously It's more expensive to react to disease than prevent it…if you could avoid cancer by spending $10 extra a day, it would be the right financial move; cancer costs most people over $100,000 per year to treat

Dr. Gabrielle Lyon argues we've been focusing on the wrong idea for 50 years…the problem isn't that we're over-fat, it's that we're under-muscled. Skeletal muscle makes up 40% or more of your body and is an underrecognized endocrine organ that secretes myokines (signaling molecules) when contracted, impacting the brain, liver, pancreas, and truly every body system. Yet skeletal muscle wasn't even considered an organ system until about 25 years ago! The diseases we think of as obesity-related—type 2 diabetes, Alzheimer's, cardiovascular disease—are actually diseases of skeletal muscle first, decades before symptoms appear. When Dr. Lyon asked a PCOS expert what body fat percentage contributes to infertility, the answer shocked her: "It has nothing to do with body fat percentage—it has everything to do with the fat infiltrated into the muscle, the intermuscular adipose tissue (IMAT)." The new US Dietary Guidelines (which Dr. Lyon witnessed being announced on stage) recommend 1.2 to 1.6 grams of protein per kg for the first time in history, a tremendous change based on randomized controlled trials instead of epidemiology. Her mentor, Dr. Donald Layman, wrote the protein portion of the guidelines, and 90% of those guidelines are reflected in her new book, Forever Strong Playbook, released on January 27th of this year.

In this episode, I am speaking with Dr. Loretta Breuning, who is the founder of the Inner Mammal Institute. She's the author of many personal development books, including the one that I have read of hers, which I highly recommend, and found fascinating, called Habits of a Happy Brain.

In this podcast, I am speaking with Dr. Reef Karim, a leading expert in human behavior, who has dedicated his life to educating, entertaining, and helping people understand themselves better. Dr. Karim is a double board certified psychiatrist, addiction medicine physician, relationship expert, writer, speaker (with recurring appearances on Oprah, Dr. Oz, CNN, Larry King Live, Dr. Phil, Anderson Cooper, and many others), comedic host, and media personality. We will discuss the "victim mindset" and how it appears to be rapidly spreading in the younger generations across the Western world, the difference between victimhood and vulnerability, conformism vs. authenticity/courage, healing from trauma, self-sabotaging behavior, and how to grow into the fullest expression of your own capacities and authentic self.

Dr. Izabella Wentz is a renowned pharmacist focused on thyroid health. In this episode, she reveals a shocking pattern: about 90% of people with Hashimoto's have alterations in how much cortisol they release throughout the day. They struggle with brain fog, chronic fatigue, and sleep issues—tired all day, wired at night—even when they're on thyroid medications. She's discovered something fascinating about "adrenal fatigue" that challenges both the old naturopathic model and the skeptics. Your adrenals aren't damaged or lazy…they're perfectly capable of producing hormones. "Adrenal fatigue" is an intelligent adaptive response where your body down-regulates cortisol production to protect itself from chronic stress, essentially saying, "This is unrealistic, we can't pump out high amounts of cortisol all the time." After being forced to find solutions during years of severe sleep deprivation with her son, Dr. Wentz developed a 4-week protocol that has now helped thousands of people. By week two, people report their anxiety dropping from an 8 to a 2. By week four, their libido returns and they feel transformed, all without hormones, complicated testing, or bags full of supplements.