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20 Fat Loss Compounds Ranked Worst to Best (No GLP-1s)
May 5, 2026
Unknown duration
Saturday Morning Coffee Talk 5/2/26
May 2, 2026
2h 14m 32s
LDN | The Force Multiplier for Peptides and HRT
May 1, 2026
Unknown duration
April 2026 Solo Q&A — Every Question Answered | Hunter Williams
Apr 28, 2026
Unknown duration
Reader Mailbag 2 — Autoimmune, Fertility, Cancer & More | Hunter & Taylor Williams
Apr 24, 2026
Unknown duration
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 5/5/26 |  20 Fat Loss Compounds Ranked Worst to Best (No GLP-1s) | 👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksGLP-1s like retatrutide are the kings of fat loss. No argument there. But what do you actually do when you're cycling off, when GLP-1s aren't on the table, or when you want to stack something alongside your GLP-1 so you don't have to escalate the dose?In this video I rank 20 non-GLP-1 fat loss compounds from F-tier to S-tier. Most are peptides. A few are small molecules. Some I use all the time. Some I would never touch.I cover the mechanisms, the dosing protocols I actually run, the side effects I've personally experienced, and where each one fits in a real fat loss program. You'll get my honest take on adipotide, AOD-9604, sermorelin, setmelanotide, tesofensine, SS-31, cagrilintide, IGF-1 LR3, cardarine, CJC/ipamorelin, MOTS-c, 5-amino-1MQ, BAM15, SLU-PP-332, ATX-304, mirabegron, albuterol, HGH, and tesamorelin.Hormones and lifestyle come first. Always. But once those are dialed in, these are the tools worth knowing about.If you want my peptide cheat sheet and links to everything I use, check the description below. And if you want to ask me questions directly, come hang out in the Axion Collective. | — | ||||||
| 5/2/26 | Saturday Morning Coffee Talk 5/2/26✨ | coffee talkhealth+3 | — | hunterwilliamshealth.com | — | coffeehealth+3 | — | 2h 14m 32s | |
| 5/1/26 | LDN | The Force Multiplier for Peptides and HRT | 👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksLow-dose naltrexone is one of my favorite compounds out there, and in this updated 2026 episode I'm breaking down why it deserves a spot in your protocol. I cover the four mechanisms that make LDN work: the endorphin rebound, the OGF/OGFR axis, TLR4 antagonism, and broad anti-inflammatory signaling. Then I get into where LDN actually shines clinically. Autoimmune conditions like Hashimoto's and Crohn's. Chronic pain and fibromyalgia. Depression. PCOS and fertility. Even skin issues like acne, which I've personally dealt with for years.But the part I'm most excited about is how LDN stacks with hormones and peptides. I walk through why it pairs so well with TRT, estrogen, and thyroid optimization, and then I get into specific peptide combos including BPC-157, TB-500, thymosin alpha-1, KPV, SS-31, and GLP-1 agonists. I also share why LDN might let you stay at lower GLP-1 doses for longer.I cover dosing, titration, side effects, and my own experience cycling versus staying on continuously. If you're already optimizing with peptides and hormones, LDN might be that last five to ten percent that makes everything else work better.00:00 – Intro and why LDN deserves an updated episode02:22 – Why LDN belongs in your protocol (40-year safety record, broad benefits)03:44 – The history of LDN and Dr. Bernard Bihari's HIV discovery05:42 – The four mechanisms of action explained06:30 – The OGF/OGFR axis and cancer applications07:30 – TLR4 antagonism and the immune benefits09:24 – Where LDN shines: autoimmune, pain, gut, depression, PCOS, skin13:14 – Dosing, titration, and timing (night vs morning)15:06 – Side effects, contraindications, and safety16:14 – LDN and hormone replacement therapy synergy18:34 – LDN for men on TRT, sexual function, and cortisol20:48 – LDN stacked with peptides (BPC-157, TB-500, KPV, SS-31, GLP-1s, TA-1)28:38 – My personal take on cycling vs daily use30:16 – Closing thoughtsTimestamps | — | ||||||
| 4/28/26 | April 2026 Solo Q&A — Every Question Answered | Hunter Williams | Every question that came in over the last month. No filters, no shortcuts. This is the April 2026 edition of the solo Q&A and Hunter covers everything from women's hormone optimization and PCOS to vasectomy impacts on men's health, peptides for neurological conditions, bioregulator cycling protocols, and everything in between.For research and entertainment purposes only.0:00 — Intro & How Hunter Organizes Q&A Questions1:21 — Email List & Axion Collective2:17 — Category: Women's Health & Hormones2:21 — Kisspeptin Added to TRT — Does It Help Libido & Muscle for Women?3:43 — Free Testosterone Doubled on GHK-Cu But Feeling Nothing — Reduce HRT?4:39 — What Are Truly Optimal Estrogen & Testosterone Levels for Women?5:58 — Peptides for Women Focused on Health Optimization & Longevity6:41 — Deep Dive on PCOS for Women in Their Late Teens & Early Twenties7:44 — Can Peptides Help Bring Up a Low White Blood Cell Count?8:18 — No-Sting Reconstitution Water & GHK-Cu — Buccal Strips vs Injections11:03 — Category: Men's Health11:03 — Vasectomy Impact on Men's Health & Bioregulators Before & After12:05 — Hit a Plateau on Testosterone — What to Look at Next?12:28 — Best Peptides for Post Cycle Therapy13:33 — PEG-MGF for Real World Use as a Healing Peptide14:41 — Category: Specific Disease States14:50 — Peptide Protocol for Hepatitis C15:23 — Peptides That Help With High Blood Pressure16:28 — Myelin Regeneration & Protection for MS17:10 — FND Diagnosis After Ischemic Stroke — What Peptides Might Help?17:58 — Kidney Transplant & Anti-Rejection Meds — Peptides Worth Exploring?18:57 — Dihexa for Alzheimer's Protocols & Stacks19:35 — Urolithin A & P-21 for an 87-Year-Old With Neurodegenerative Issues20:25 — Amidated vs Non-Amidated P-21 — Does It Matter & How to Dose?21:27 — Does Retatrutide Count Toward the 15mg Weekly Tirzepatide Max?22:17 — Is Metformin Still the Best Longevity Compound?23:10 — Category: Performance & Mitochondrial Health23:15 — Are There People Who Don't Respond to MOTS-C?24:31 — L-Carnitine Timing Around Thyroid Meds & Does Glutathione Cause Gray Hair?25:53 — Had Great Results on 250mcg SLU — Go Higher or Diminishing Returns?26:51 — BAM-15 & SLU Dosing, Cycling & Peptide Refrigeration Shelf Life28:22 — Category: Growth Hormone Peptides28:30 — Optimal Tesamorelin Dose for Non-HIV Use, Stacking With Ipamorelin & Storage30:59 — MK-677 Deep Dive — Using It on Breaks From CJC & Ipamorelin32:05 — Anaphylactic Reactions to Sermorelin After a Year of Use — What Causes This?33:38 — GHK & AHK for Hair Loss, Gray Hair Reversal & Skincare34:32 — Category: Stacking Protocols34:38 — Guidelines for Introducing & Stacking Peptides — Protocol or Symptom Based?36:01 — SLU-PP-332 Pills vs Injection — Which Is Better?36:24 — Best Practice for Reconstituting Ara-290 for Chronic Neuropathy37:20 — Could Thymosin Alpha-1 Trigger a Negative Immune Response & Spike CRP?38:33 — Yearly Bioregulator Cycling Protocol Document40:51 — Closing Thoughts & Thank You👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links | — | ||||||
| 4/24/26 | Reader Mailbag 2 — Autoimmune, Fertility, Cancer & More | Hunter & Taylor Williams | Hunter and Taylor are back for another Reader Mailbag — six questions, real answers, no shortcuts.This week: building a peptide protocol for autoimmune disease in women, Hunter and Taylor's personal fertility journey on TRT, how to think about peptides and cancer risk, optimizing health for seniors stuck on statins, muscle preservation for perimenopausal women on GLPs, and everything you need to know about reconstitution, mixing peptides, and nasal sprays.Submit your questions for the next episode at the link in the show notes.For research and entertainment purposes only.👇 START HERE📋 Free Peptide Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheet👥 Join the Axion Collective: https://theaxioncollective.manus.space/📖 Get My Book: https://a.co/d/avbaV48🌐 Website: https://hunterwilliamshealth.com/💊 Supplement Sources: https://hunterwilliamssupplements.carrd.co/🛒 Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA🎙️ Submit a Video Topic: https://hunterwilliamsvideotopic.carrd.co/📱 Instagram: https://www.instagram.com/hunterwilliamscoaching/Follow Taylor: https://www.youtube.com/channel/UCdVIB4TuAfycl0CmaaExSXwhttps://www.instagram.com/taylorwilliamscoaching | — | ||||||
| 4/21/26 | Is C02 Therapy The Ultimate Biohack? | In today's episode, we're taking a detour from our usual peptide discussions to dive into one of my absolute favorite biohacking devices: the carbon dioxide therapy inhaler from CarboGenetics. I know what you're thinking—why would we want to inhale CO2 when we usually focus on getting more oxygen? It all comes down to a fascinating physiological mechanism called the Bohr effect. I'll break down the science of how inhaling small amounts of carbon dioxide actually forces your hemoglobin to release more oxygen into your tissues, significantly boosting cerebral blood flow, accelerating wound healing, and enhancing exercise performance. We'll explore the history of CO2 therapy, from ancient volcanic vents to modern clinical studies showing impressive results in tumor oxygenation and hearing recovery. I'll also share my personal routine for using the device, including the optimal concentrations and timing for morning wakefulness, pre-workout endurance, and afternoon brain energy. Whether you're a hard-charging entrepreneur looking to regulate your nervous system or an athlete wanting an edge in the gym, this affordable biohack might just be the missing piece in your wellness routine. Tune in to learn how to harness the power of the carbonated body!Buy Carbogenetics Here(code HUNTERW for 15% off): https://carbogenetics.com/co2inhaler/The Carbonated Body Book: https://thecarbonatedbody.com/Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 4/18/26 | Saturday Morning Coffee Talk 4/18/26 | Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 4/17/26 | The FDA Just Changed Everything for Peptides | My Honest Take | Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Today I'm breaking down something that's been blowing up in the peptide world. The FDA just made a major announcement about moving 19 popular peptides from Category 2 to Category 1. And I want to share my honest thoughts on what this actually means for you.First I walk through how we got here. The Biden administration's original scheduling decision. The rise of the research peptide market. And why roughly four out of five peptides consumed in the US today come from research companies.Then I get into what the FDA is actually proposing. The July hearing. The February 2027 timeline. And what Category 1 status would mean for compounding pharmacies and telehealth clinics.But here's where it gets interesting. I share my prediction on where prices are headed and why I think we'll eventually see price parity between prescribed and research peptides. I also dig into what I think is a quiet quid pro quo happening between Big Pharma and the FDA around GLP-1s.This is speculation on my part. I'm not a doctor or a lawyer. But I wanted to give you my honest read on where this is all going. Let me know your thoughts in the comments.Timestamps00:00 — Intro and disclaimers (not a doctor, not a lawyer)01:40 — History: How the Biden FDA scheduled 19 peptides as Category 202:44 — The rise of the research peptide gray market (4 out of 5 peptides)04:18 — RFK on Joe Rogan and the FDA's Category 1 plans04:58 — What Category 1 actually means (Sermorelin example)05:42 — The July hearing and February 2027 final say timeline07:18 — FDA cracking down on GLP-1s from research companies08:42 — More compounding pharmacies and telehealth clinics entering the space09:08 — The Metformin analogy and future price parity13:20 — The rug pull theory: FDA and Big Pharma quid pro quo on GLP-1s14:04 — Why Eli Lilly is protecting retatrutide (projected $50B/year product)17:04 — Final thoughts and the golden age of peptides | — | ||||||
| 4/10/26 | Hunter & Taylor Answer Your Most Pressing Health Questions | Reader Mailbag Episode 1 | Hunter and Taylor Williams sit down for their first ever Reader Mailbag episode — a brand new deep dive Q&A format where they take the questions that need more than 60 seconds and actually break them down together.Most Q&As are rapid fire. This one isn't. Hunter and Taylor go deep on some of the most common but most underanswered questions they receive — covering women's hormones, reproductive health, peptides, detox protocols, pre-workout stacks, and whether teens should ever be using peptides at all.This week's questions:Should a 33-year-old female with low hormones start one hormone at a time — and if so, which one first? Hunter and Taylor break down why progesterone is the first building block, how to dose it by symptom relief rather than blood work numbers, and why more women in their 20s and 30s are candidates for testosterone than most people realize. They also get into why injectable testosterone beats cream for most women, how birth control is blocking natural hormone production, and what's really causing the epidemic of low mood, no libido, anxiety, and irregular periods in younger women.Can peptides help treat ovarian cysts without surgery? Hunter and Taylor discuss why PCOS is really a metabolic condition — not a testosterone problem — and why metformin plus a GLP-1 may be more effective than a $20,000 surgery. They also break down how often lifestyle modification is skipped in favor of the operating table.If a woman is already on TRT, can Kisspeptin further help with libido and muscle gain? They cover the difference between Kisspeptin 10 and Kisspeptin 54, the brain study showing Kisspeptin's direct effect on libido, and why it's not a replacement for hormone therapy but can be a useful add-on.What are the anti-aging benefits of Melanotan beyond tanning? Taylor shares her experience with Melanotan's cognitive and vision benefits, how it amplifies even limited sun exposure in the winter months, its immune system benefits, and what it actually does to hair pigmentation.What does Hunter's pre-workout stack actually look like? Injectable DADA, L-carnitine, choline, ATP, and phosphocreatine — plus the DIY powder formula he used to make from bulk supplements including beta alanine, citrulline malate, creatine, taurine, and EAAs. Taylor also shares why she can't stomach most commercial pre-workouts and what she uses instead.Beyond weekly glutathione, what else can you do to protect your body from environmental toxins and pesticides? Taylor's fruit and vegetable cleaning protocol, sauna, zeolite, activated charcoal, spirulina, and ion cleanse foot detox baths — plus a conversation about roundup in the air and why everyone should be detoxing regardless of how healthy they are.Should teens ever use peptides — for acne, weight loss, ADHD, or sports injuries? Hunter and Taylor break down which peptides they think are appropriate in context, why BPC-157 and TB-500 for a teen athlete with an injury makes more sense than doxycycline for acne, and why the hard and fast rule of "never until 18" doesn't hold up when teens are already being prescribed antibiotics and birth control.Submit your questions for future Reader Mailbag episodes at the link in the show notes.⚠️ For research and entertainment purposes only. ⚠️👇 START HERE📋 Free Peptide Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheet👥 Join the Axion Collective: https://theaxioncollective.manus.space/📖 Get My Book: https://a.co/d/avbaV48🌐 My Website: https://hunterwilliamshealth.com/💊 Supplement Sources: https://hunterwilliamssupplements.carrd.co/🛒 Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA🎙️ Submit a Video Topic: https://hunterwilliamsvideotopic.carrd.co/📱 Instagram: https://www.instagram.com/hunterwilliamscoaching/ | — | ||||||
| 4/7/26 | The 5 Most Overrated Peptides (And What I'd Use Instead) | Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/One of the most common questions I get is which peptides I actually hate. And honestly, it's a fair thing to ask. You're spending real money on these compounds, so you deserve to know which ones might not be worth it.In this episode, I break down my five most overrated peptides. None of these are dangerous. Most have legitimate research behind them. They've just been surpassed by better compounds that cost about the same and work significantly better.I cover AOD-9604 and why the clinical trials underwhelmed, GHRP-2 and GHRP-6 and the cortisol and hunger problems they create, HGH Frag 176-191 and why it's somehow worse than AOD, Sermorelin and why I think it persists despite better options being available, and oral 5-Amino-1MQ capsules versus the injectable form.For each one, I share what I'd use instead. Tesamorelin, GLP-1 agonists, Ipamorelin with CJC-1295, and the injectable version of 5-Amino are all on the table.This isn't a hit piece. Every peptide on this list works for someone. I just don't think most people are getting their money's worth. Take it as one peer's honest opinion and test things for yourself. | — | ||||||
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| 4/3/26 | March 2026 Q&A | GLP-1s, GH Peptides, Healing, Autoimmune & More | Hunter Williams | Hunter Williams answers your March 2026 submitted questions across six categories — GLP-1s, growth hormone secretagogues, healing & injury recovery, metabolic peptides, men's health, and autoimmune support.Topics covered in this episode:Tirzepatide at max dose (15mg) — what to do when you've plateaued and how to transition to retatrutide safelyRetatrutide side effects — nausea, gut shutdown, sensitivity after restarting, and dose adjustmentsStacking tirzepatide and retatrutide — why it's not dangerous and the strategic reason to combine themCagrilintide + tirzepatide for appetite suppression and A1C managementGLP-1 non-responders — why some people don't respond and what to use insteadJardiance (SGLT2) alongside retatrutide — red blood cell considerations and cyclingBest peptide stacks for muscle building and body recomp on GLP-1sTesamorelin vs CJC-1295/Ipamorelin for belly fat and visceral fat reductionHGH vs peptide secretagogues for women 55+ — longevity, muscle, and brain healthGH secretagogues for female athletes with RED-S and absent menstrual cycleBPC-157 and anhedonia — dopamine effects and alternatives (TB-500, Cardilax, PEG-MGF, GHK)Pre and post-op peptide protocols for faster surgical recoveryMOTS-c, methylation mutations (MTHFR/COMT), and why some people feel more fatigued5-Amino-1MQ stacked with retatrutide — dosing caution and injectable vs oralMethylene blue, 9-ME-BC, Adamax, and Semax as nootropicsPeptides for hypothalamus and pituitary repair after brain tumor removalSelank, Noopept, and oxytocin for social anxiety and confidenceThymosin Alpha-1 for autoimmune disorders like lupusPost-prostatectomy libido restoration — testosterone, DHT, estradiol, and provironUrolithin-A and spermidine dosing for mitophagy and autophagyJoin the Axion Collective for live coaching calls every Thursday at 8PM Eastern. Submit your questions for next month's Q&A via the link in the description.Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 3/31/26 | Survodutide & Mazdutide | The GLP-1/Glucagon Duo That Could Rival Reta | Join My Private Group: https://theaxioncollective.manus.space/Website: https://hunterwilliamshealth.com/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I'm breaking down two peptides that I think are about to blow up: mazdutide and survodutide. Both are GLP-1 and glucagon dual agonists. Think of them like retatrutide minus the GIP component. And that glucagon piece is what makes them special.I go through the trial data for both compounds. We're talking up to 21% weight loss with mazdutide and 80% liver fat reduction. Survodutide earned FDA breakthrough therapy designation for MASH based on a 62% resolution rate. These are serious numbers.Here's what most people don't realize. These two peptides are NOT the same. Mazdutide runs close to a 50/50 split between GLP-1 and glucagon agonism. Survodutide is roughly 8 to 1 in favor of GLP-1. That changes everything about tolerability, appetite suppression, and how much metabolic burn you're actually getting.I also cover practical use cases. Cycling off reta without losing momentum. Choosing between the two based on whether you need more appetite control or more energy expenditure. Dosing guidance for people just starting out. And why escalating too fast is still the number one mistake people make with GLP-1 peptides. | — | ||||||
| 3/28/26 | Saturday Morning Coffee Talk 3/28/26 | www.hunterwilliamshealth.comwww.axioncollective.manus.space | — | ||||||
| 3/27/26 | Peptides & Longevity Medicine Explained by a Real Cardiologist | Dr. Abid Husain, MD | Dr. Abid Husain is a triple board-certified cardiologist in cardiology, internal medicine, and functional medicine. After years in the traditional hospital system in New Jersey, he walked away to focus on what actually prevents disease — and now practices at the Boulder Longevity Institute, combining conventional medicine with peptides, HRT, and longevity protocols.This is one of the most important conversations we've had on the podcast. If you're using hormones, peptides, or GLPs — or you're thinking about it — you need to hear what a real cardiologist has to say about all of it.In this episode, Hunter and Dr. Abid cover why cholesterol alone is a terrible predictor of heart disease, what APOB and particle size actually tell you, and why the AI-powered cardiac imaging most people have never heard of is the real state of the art. They break down the testosterone and heart disease myth — fully debunked — along with hematocrit, blood clots, and what's actually dangerous on TRT. They cover the Women's Health Initiative, why bioidentical and synthetic hormones are not the same thing, and what women of any age need to know about HRT.Then the conversation shifts to peptides — how BPC-157, TB-500, and Thymosin Alpha-1 benefit the cardiovascular system, what the SELECT trial proved about GLPs and heart health, why synthetic growth hormone and secretagogues are completely different, and how to think about cancer risk before starting GH protocols. They close with SS-31, Humanin, MOTS-C, and why the order you use mitochondrial peptides in actually matters — plus a deep dive into SGLT2 inhibitors, the most underrated longevity drug almost nobody in this space is talking about.Episode 3 of The Hunter Williams Podcast.https://hunterwilliamshealth.com/Podcast───────────────────────────CONNECT WITH DR. ABID HUSAIN───────────────────────────📱 https://www.instagram.com/dr_abidhusain/🌐 https://boulderlongevity.com/▶️ https://www.youtube.com/@DoctorAbidHusain───────────────────────────CONNECT WITH HUNTER WILLIAMS───────────────────────────🌐 https://hunterwilliamshealth.com/📱 https://www.instagram.com/hunterwilliamscoaching/DISCLAIMERThis podcast is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any new health protocol. | — | ||||||
| 3/24/26 | Dihexa Deep Dive | Dosing, Safety, and Why I Keep Coming Back to It | Join My Private Group: https://theaxioncollective.manus.space/Website: https://hunterwilliamshealth.com/https://hunterwilliamshealth.com/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I'm doing a full deep dive on Dihexa. A synthetic peptide and nootropic that I think hits the perfect sweet spot for cognitive enhancement.I break down what Dihexa actually is. How it was developed at Washington State University. And how it works in the brain through the HGF/c-MET pathway to drive synaptogenesis.I also cover the scandal. The PhD revocation, the retracted papers, and the $14 million in settlements from the biotech company that tried to bring a Dihexa pro-drug to market. Spoiler. The pro-drug didn't really work, but Dihexa itself is a different story.I walk through the animal studies, the limited human trial data, and what we actually know about safety. Including the cancer pathway concern and why cycling matters.Then I get into practical dosing. Oral, sublingual, injection, intranasal. What I personally take (10mg oral, three times a week) and why I pair it with Alpha GPC on off days.If you're curious about nootropics but don't want something that turns you into a robot, this one's for you. I share my honest perspective on where Dihexa fits in the toolkit alongside compounds like Cerebrolysin and P-21. | — | ||||||
| 3/20/26 | The Next Big Things in Biohacking | EMF, Peptides, and Superhuman Performance with Alex Kikel | Hunter and Taylor sit down in person with Alex Kikel — biohacker, performance coach, and one of the most forward-thinking minds in the peptide and longevity space — for one of the most information-dense conversations the podcast has ever had.In this episode, they go deep on the science of coherent vs. non-coherent EMF and why it matters more than most people realize, structured water and how your environment is either working for or against your biology, and the cutting-edge peptide molecules Alex believes will define the next era of human optimization — including KLP-1, VD-11, and FoxO3.They also cover GLP-1s and where the conversation is really headed, fertility and pregnancy optimization for couples on hormone therapy, postpartum recovery protocols, non-androgenic muscle building strategies, PBO walks and active manifestation, and Alex's vision for what a true "super molecule" could mean for human evolution.Whether you're deep in the biohacking world or just getting started, this episode will challenge how you think about your health, your environment, and what's actually possible.Watch on Youtube: https://youtu.be/tYscWLLPkDE | — | ||||||
| 3/17/26 | Spermidine for Longevity | Join My Private Group: https://theaxioncollective.manus.space/Website: https://hunterwilliamshealth.com/https://hunterwilliamshealth.com/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 3/14/26 | Saturday Morning Coffee Talk 3/14/26 | www.hunterwlliamshealth.com | — | ||||||
| 3/13/26 | Peptide Secrets Revealed: BPC-157, TB-500, GLP Microdosing & Hormones with Sarah Morgan | Peptide foundations, GLP micro-dosing, hormone optimization, and the peptides most people are using wrong — Hunter Williams and Taylor sit down with Sarah Morgan, nutritional biochemist and founder of Amino Academy, for one of the most educational peptide conversations on the internet.Sarah comes from a family of cardiologists, holds a Master's in Nutrition from the University of Bridgeport, and has 20 years of clinical practice. She's one of the sharpest voices in the peptide space — and this is the inaugural episode recorded in Hunter & Taylor's brand new studio.In this episode:The real difference between Thymosin Beta-4 and TB-500 — and when to use eachWhy you should NEVER combine BPC-157, TB-500, GHK, and KPV in the same vialCycling peptides vs. staying on them — the receptor resistance conversation no one is havingGLP microdosing explained: what it actually means, who it's for, and why it's NOT about weight lossWhy peptides won't work if your hormones and inflammation aren't addressed firstThe mast cell / histamine connection to secretagogue reactions (and what to do about it)Mitochondrial peptide stacking: MOTS-c, SS-31, Humanin — order mattersNAD: powerful tool or overused crutch?Thymosin Alpha-1 — the most underrated peptide in the spaceDihexa, Epitalon, Glutathione, and the future of peptide delivery formatsHair loss on GLPs — what's actually happeningHormones as the foundation: why estrogen is a hero for women AND menThe metabolic aging events at age 44 and 60 — how to get ahead of themSarah's Amino Academy course — what's in it and who it's forWant to go deeper on everything Sarah covered in this episode? Amino Academy is the most comprehensive peptide education course available — built for anyone who wants to actually understand the science, not just follow trends.https://aminoacademy.com/home?am_id=hunterCODE: HUNTER20 for 20% off course Connect with Sarah Morgan https://www.sarahmorgan.co https://www.instagram.com/sarahmorgan.coConnect with Hunter Williams https://hunterwilliamshealth.com/ https://www.instagram.com/hunterwilliamscoaching/Connect with Taylor Williams https://www.instagram.com/taylorwilliamscoaching/ https://www.youtube.com/@taylorwilliamscoachingThe Hunter Williams Podcast explores peptides, hormones, biohacking, and optimizing human performance. New episodes drop weekly. | — | ||||||
| 3/10/26 | Hematocrit on TRT Explained | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/A lot of guys get on TRT, see their hematocrit go up, and immediately get told they need to start donating blood or doing routine phlebotomy. In this episode, I break down why that conversation is usually way more nuanced than most people realize. I walk through what hematocrit actually is, why testosterone raises it, and why a higher number on paper does not automatically mean something is dangerous. We talk about how hydration status, sauna use, cardio, lab timing, sleep apnea, insulin resistance, inflammation, and metabolic health all change what that number really means in the real world. I also explain why I think routine blood donation is often overused in men on TRT and how it can create its own problems by driving down iron and ferritin. Most importantly, I give you a practical framework for when I think hematocrit is usually a non-issue, when it deserves more attention, and what I would adjust before ever jumping straight to phlebotomy. This is a deeper dive into one of the most misunderstood topics in testosterone therapy, and my goal is to help you think about it with a much better framework. | — | ||||||
| 3/6/26 | DADA Deep Dive | My Updated Take on an Underrated Performance Enhancer | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I’m revisiting DADA, a compound I first talked about a couple years ago, and giving you my updated thoughts now that I’ve personally used it for a long time. I break down what DADA actually is, how it works as a metabolic modulator, and why I view it as one of the most underrated performance-enhancing tools in this category. To me, it feels very similar to MOTS-c in practice, but in some cases it may even give a stronger performance edge.I walk through the mechanism behind DADA, including how it affects PDK and PDH to improve mitochondrial energy production, glucose oxidation, ATP output, and metabolic flexibility. I also explain why I think many people notice better training endurance, better pumps, improved cardio capacity, and the ability to push harder before hitting that wall of fatigue and lactate buildup.I also cover the human data we do have, especially around liver health, fatty liver disease, and lipid markers, along with how I personally think about dosing, why I prefer injectable use for performance, and where people need to be careful not to overdo it. This is an updated, practical breakdown of why DADA has become a staple in my own routine. | — | ||||||
| 2/28/26 | Saturday Morning Coffee Talk 2/28/26 | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 2/27/26 | Peptides & Mast Cell Activation | What You Need to Know + How To Fix It | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I’m diving deep into Mast Cell Activation Syndrome, or MCAS, and why it’s such a big topic in the peptide world. If you’ve been around peptides long enough, you’ve probably seen it — certain people react strongly to compounds like CJC, ipamorelin, or other common peptides, and suddenly they’re dealing with flushing, hives, GI distress, tachycardia, or brain fog.I break down what MCAS actually is, why some people are genetically predisposed, and why others develop it from environmental triggers, infections, autoimmune issues, or nervous system dysregulation. I also explain why traditional antihistamines often fall short — because they treat symptoms, not the upstream immune imbalance.Then I walk through my comprehensive MCAS stack: LDN, Thymosin Alpha-1, Thymalin, KPV, VIP, PEA, and even GLP-1 receptor agonists. I explain the mechanisms, dosing strategies, when to introduce each one, and how to think about this in phases instead of expecting a magic bullet.This isn’t a cure-all, but it’s what I’ve seen work coaching hundreds of people. If you’re sensitive to peptides or trying to get back to baseline after reactions, this episode will give you a structured roadmap. | — | ||||||
| 2/20/26 | February 2026 Q&A | GLPs for Pain, Mast Cell Fixes, Microdosing Reta & More! | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ | — | ||||||
| 2/13/26 | FOXO4-DRI | The Senolytic “Tune-Up” Peptide for Healthy Aging | Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I’m breaking down one of the most misunderstood longevity peptides out there, FOXO4-DRI. It’s a senolytic, meaning it’s designed to help clear senescent “zombie cells” that accumulate over time from stress, aging, inflammation, and environmental load. Think of it like a tune-up for the body. It’s not a peptide you run for fat loss or acute injury healing. This is the kind of compound you may use once or twice per year to help keep the internal ecosystem cleaner, less inflamed, and functioning at a higher level.I walk you through what FOXO4-DRI is, where it came from, and the core mechanism that makes it interesting. Specifically, how it disrupts the FOXO4–p53 interaction inside senescent cells, triggers apoptosis, and largely spares healthy tissue. Then I cover what the animal data actually shows, what we can realistically expect in humans, and why the effects can feel “cumulative” over a few weeks, similar to how some people describe SS-31.I also share my personal reason for using it right now in the context of fertility and overall health optimization, plus the dosing strategies I’ve seen online versus the protocol I personally prefer.Want more direct access? Join my email list and check out Axion Collective for live Thursday night coaching calls. | — | ||||||
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