The Dr. Hyman Show

If we're wired for joy, why do so many successful people feel exhausted, disconnected, or emotionally flat? On this episode of The Dr. Hyman Show, I sit down with psychiatrist, researcher, and author Dr. Judith Joseph, whose team conducted the first peer-reviewed clinical study on high-functioning depression. We talk about why feeling "fine" on the outside doesn't always reflect what's happening beneath the surface—and why so many people struggle to feel fully alive. You’ll learn: Why achievement and productivity don't always lead to fulfillment How to tell whether you're burned out—or struggling with high-functioning depression The surprising connection between unresolved trauma, people-pleasing, and chronic stress What your phone, social media habits, and screen time may be doing to your mood How to start reclaiming joy when life feels flat, exhausting, or unfulfilling Like many people, I've spent periods of my life focused on achievement and productivity, believing fulfillment would follow. I've learned that the most important work isn't always doing more—it's understanding what's keeping us from fully experiencing joy in the first place. Want to explore this further? Dr. Judith Joseph offers several self-assessments under the "Quiz" tab on her website, including tools for anhedonia, high-functioning depression, and trauma. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Big Bold Health, BIOptimizers, Rho, Sunlighten, Paleovalley, and Pique. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Visit sunlighten.com and use code HYMAN to save up to $2100 today. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. (0:00) High functioning depression, burnout, and Dr. Hyman's personal experience (2:37) Introduction Dr. Judith Joseph (5:13) Depression among medical professionals and defining anhedonia (7:04) Joy as part of our DNA and identifying high functioning depression (13:23) Biological causes, biomarkers, and differences between burnout and high functioning depression (18:18) Avoiding trauma processing by staying busy; hedonism and anhedonia (22:14) Identifying roots of trauma, childhood patterns, and using transitional objects (25:51) Finding points of joy amidst depression and people pleasing in high-functioning individuals (30:39) Neurological shifts, lack of joy, and the biopsychosocial model of depression (36:56) Digital depression, reducing screen time, and healthy tech relationships (49:09) Women's hormones, midlife shifts, and distinguishing hormonal from psychiatric conditions (58:30) Reclaiming joy, the five v's, and processing emotions (1:01:21) The significance of venting, emotional boundaries, and healthy outlets (1:05:28) Defining values, mind-body connection, and social relationships (1:09:05) Planning and scheduling future joy and connection (1:13:22) The evolution of psychiatry, spirituality, and Gen Z's spiritual study (1:18:03) Finding meaning, purpose, and learning more about high functioning depression

Depression is often treated as a single condition. But two people with the same diagnosis can have completely different underlying causes. On this episode of The Dr. Hyman Show, I’m rejoined by Dr. James Greenblatt to explore why depression may be less of a disease and more of a signal that something deeper is going on. We discuss how a root-cause approach can uncover what’s driving symptoms and why finding what’s beneath them matters. Watch the full conversation on YouTube or listen wherever you get your podcasts. We discuss: Could nutrient deficiencies, inflammation, or gut issues be contributing to symptoms of depression What tests can help uncover the biological factors that may be affecting mood and mental health Why can two people with depression have different root causes—and require different solutions How do blood sugar imbalances, hormone changes, and metabolic health influence the brain What should you know about antidepressants, tapering, and addressing the factors that may affect recovery Hope doesn't come from ignoring symptoms—it comes from understanding them. Sometimes the most important question isn't "What's wrong with me?" but "What might my body be trying to tell me?" One of the key themes in this conversation is that mental health is deeply connected to what's happening throughout the body. In my Brainshaping Academy, you'll learn how to support the biological systems that shape cognitive, emotional, and mental well-being. View Show Notes From This Episode Depression symptoms aren’t always just “in your head.” Dr. Hyman’s Brainshaping Academy shows how your gut, immune system, and nutrient levels may be responsible—and what you can do about it. → https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Made In Cookware, Perfect Amino, BON CHARGE, and Big Bold Health.Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.Visit madeincookware.com and use code HYMAN10 for 10% off your order.Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.Head to boncharge.com/hyman and use code HYMAN for 15% off.Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. (0:00) Antidepressants, Cooking at Home, and Introducing the Brain Shaping Academy (3:14) Prevalence of Depression and Personal Stories (4:27) Exploring Root Causes of Depression (5:07) Influential Figures and Orthomolecular Psychiatry (12:29) Gut Health, Gluten Sensitivity, and Brain Inflammation (20:22) Neuroinflammation and Root Causes of Depression (22:10) Biomarkers, Hormonal Imbalances, and Insulin Resistance (25:34) The Role of Toxins and Diagnostic Testing (31:15) Case Studies and Patient Stories (34:29) Challenges in the Mental Health System (37:05) Effectiveness of Antidepressants and Patient Resistance (43:17) Role and Need for Nutritional Lithium (45:00) Sponsor: Big Bold Health (46:00) Identifying Nutritional Lithium Need (47:13) Integrating Modalities and Supplements vs. Medications (48:04) Psychotherapy Methods and Addressing Root Causes (49:34) Dr. Greenblatt's Book and the Finding a Living Platform (51:03) Systematic Approach and Global Impact of Depression (52:39) Sharing, Disclaimer, and Closing Remarks

For far too long, many women have been told their symptoms were normal, exaggerated, or simply something they had to live with—treated as isolated problems instead of part of a much larger hormonal transition happening inside the body. On this episode of The Dr. Hyman Show, I’m joined by Dr. Sharon Malone, host of The Second Opinion podcast and Chief Medical Advisor at Alloy Women’s Health. We discuss how menopause and hormone therapy became so misunderstood, the real story behind the Women’s Health Initiative study, and why a more individualized, prevention-focused approach to women’s health is long overdue. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We explore: Why so many women enter perimenopause completely unprepared—and how symptoms can begin years before menopause officially starts What the Women’s Health Initiative actually found, and how one medical narrative reshaped women’s healthcare for decades How menopause affects far more than reproduction, including the brain, heart, sleep, metabolism, and bone health What you should know about hormone therapy today, including timing, individualized treatment, and understanding risk in context The daily habits that still matter most for healthy aging, whether or not you choose hormone therapy Midlife health should never be reduced to “just deal with it.” The more women understand what’s happening inside their bodies, the earlier they can take steps to protect their long-term health and quality of life. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - ⁠Click Here⁠ Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Paleovalley, Pique, Perfect Amino, Rho, Sunlighten and BIOptimizers. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. (0:00) Introduction, survey on hormone use, and Dr. Sharon Malone’s expertise (4:04) Importance of women's health research and historical neglect (5:35) Lack of education and preparation for menopause (6:28) Societal and historical biases in women's health (9:05) Observational studies vs. randomized controlled trials (13:30) Life cycles, hormonal changes, and stages in women (19:26) Detailed stages of hormonal changes and perimenopause (23:00) Misdiagnosis and definition of menopause (25:02) The term "postmenopausal" and its significance (26:34) Impact of menopause on organ systems and major symptoms (31:19) Lifestyle factors and hormone therapy options (39:25) Black box warning, Women’s Health Initiative, and therapy timing (45:00) Women's Health Initiative findings and breast cancer risk (47:57) Reinterpreting breast cancer risk and black box warning (53:21) Personalized hormone therapy and clinical diagnosis (59:55) Importance of estrogen and bioidentical vs. synthetic hormones (1:03:35) Addressing sexual health and testosterone use for women (1:08:05) FDA-approved peptides for women’s arousal disorder (1:09:57) Long-term benefits of hormone therapy (1:12:43) Early menopause, hormone therapy, and health impacts (1:15:07) Estrogen’s role in brain health and dementia prevention (1:16:22) Alzheimer’s risk in women and hormonal

We’re surrounded by plastics and environmental chemicals every day, but only recently have scientists begun to understand how deeply they may be affecting human health. On this episode of The Dr. Hyman Show, I sit down with Dr. Shanna Swan to explore what the latest science reveals about plastics, fertility, hormone health, and the everyday habits that may be shaping our biology more than we realize. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We Examine: • Why scientists are increasingly concerned about declining sperm counts, fertility, and hormone health • What microplastics, phthalates, BPA, and PFAS actually do inside your body • Why heating food in plastic can dramatically increase exposure to endocrine-disrupting chemicals • The practical changes that may help you reduce exposure and support long-term health This conversation isn’t about fear, rather it’s about understanding how everyday exposures shape our health and where small, practical changes can make a meaningful difference. If this episode has left you thinking differently about everyday exposure and you want to learn more, here are a few great places to start: • Watch The Plastic Detox • Explore Dr. Swan’s work through the Action Science Initiative • Visit UnplasticYourLife.com for practical ways to reduce exposure at home View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Big Bold Health, Timeline, BON CHARGE, Sulighten and BIOptimizers. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of new starting price of $79. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. (0:00) Microplastics in the human body and their sources (0:56) Introduction to Dr. Shanna Swan (3:34) The Plastic Detox documentary and endocrine disruptors (5:21) Dr. Swan's research journey and phthalates (6:29) Decline in sperm count and reproductive impacts (8:45) Early research and phthalate syndrome in humans (11:03) Sources and broader impact of endocrine-disrupting chemicals (19:38) Classes of hormone-altering chemicals and health impacts (22:51) Health impacts beyond reproduction (24:20) Personal and clinical experiences with microplastics (27:02) Measuring microplastics and routes of human exposure (29:29) Methods to reduce microplastic exposure (31:14) Biological and regulatory aspects of microplastics (35:02) Plastic Detox movie findings and intervention results (41:16) Chemicals in microplastics and their effects (47:21) Legislation and consumer protection against toxic chemicals (50:54) Diagnostic testing for toxic exposure: importance and costs (53:09) Practical steps to reduce chemical exposures (55:35) Avoiding plastic and toxic exposures in daily life (58:10) Skincare, fragrance, and chemical exposure (1:01:19) Rapid-fire questions on health and environmental practices (1:09:06) Resources for testing and exposure reduction

Most health and fitness advice for women is based on research done in men. That’s something we need to rethink. On this episode of The Dr. Hyman Show, I sit down with Dr. Stacy Sims, an exercise physiologist and leading researcher in women’s health. Her work has focused on how female physiology actually changes over time—and how training and nutrition need to change with it. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We explore: • Why eating less and doing more cardio can make fat loss harder • What actually changes in your metabolism in your 30s and 40s • How to train for strength—and why it matters for long-term health • Why most workouts aren’t building muscle (and what to do instead) • How to eat and time protein to support recovery, energy, and better sleep A lot of the advice women have been given doesn’t account for how the body actually changes. Adjusting how you train and eat can make a meaningful difference in your energy, strength, and long-term health. If you’re interested in learning more, Dr. Stacy Sims is offering my listeners 15% off her online courses with the code DRSTACYSIMS15OFF. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Rho, Pique, Perfect Amino, Sunlighten, Korrus and Made In Cookware. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Visit madeincookware.com and use code HYMAN10 for 10% off your order (0:00) Women’s unique health needs, fitness, and nutrition mistakes (0:56) Introduction of Dr. Stacy Sims (3:34) Women’s health and fitness through life stages (5:39) Navigating diet, exercise, and cognitive health for women (24:00) Benefits and misconceptions of heavy weight lifting for women (30:55) Understanding anovulatory cycles and high intensity interval training (HIIT) (35:47) Reducing inflammation and proper high intensity exercise (39:11) How to properly perform HIIT (46:06) Overcoming gym intimidation and starting strength training (50:12) Importance of community, support, and lifestyle on longevity (55:01) Optimizing nutrition: circadian rhythm, time-restricted eating, and protein (1:02:44) Post-exercise nutrition and fasted vs fed workouts (1:08:01) Common nutrition mistakes for women (1:12:17) Scheduling self-care and wellness meetings (1:13:43) Quick fire questions on women’s health and fitness (1:17:40) Benefits of creatine and favorite workout snacks (1:18:23) Morning vs evening workouts and advice for younger self (1:19:28) Where to learn more about Dr. Stacy Sims and Collective X Health (1:20:20) Closing remarks, sharing, and social media (1:21:15) Disclaimer, importance of healthcare practitioners, and sponsor gratitude

Pregnancy is often filled with anticipation, excitement, and a lot of questions. But biologically, it’s also a powerful window when a baby’s metabolism and long-term health begin to take shape. On this episode of The Dr. Hyman Show, I talk with biochemist and bestselling author Jessie Inchauspé about how nutrition during pregnancy can influence a baby’s development and long-term health. Her new book, 9 Months That Count Forever, takes a closer look at the science behind these connections. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We discuss: • Why pregnancy may be one of the most important windows for shaping lifelong health • Why balancing blood sugar during pregnancy matters—and simple ways to reduce glucose spikes • The nutrients that matter most during pregnancy, from choline and protein to omega-3s • How to make healthier choices during pregnancy without added stress or confusion This isn’t about being perfect. It’s about understanding what matters most and making small, consistent choices that support both you and your baby. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Sunlighten, Qualia, Korrus, Paleovalley and BIOptimizers. Receive 20% off a subscription at timeline.com/drhyman. Visit sunlighten.com and use code HYMAN to save up to $1400. Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off. Upgrade your lighting. Enjoy 15% off at korrus.com/drhyman. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. (0:00) Impact of diet on baby's genetic plan and catching up with Jessie Inchauspé (2:08) Influence of pregnancy on new book and personal story of miscarriage (5:32) The importance of diet and placenta's role in pregnancy (9:02) Explanation and importance of epigenetics in pregnancy (12:12) Blood sugar management and pregnancy nutrition pillars (20:12) The impact of glucose on pregnancy and neurodevelopment (26:32) Managing blood sugar and gestational diabetes risks (33:50) Interpreting symptoms and the importance of protein during pregnancy (37:50) Practical dietary advice for pregnant women (41:50) The role of omega-3 fatty acids and supplementation advice (50:17) Dr. Hyman's experiences in patient care and epigenetic implications (53:52) Jessie Inchauspé's book and social media details (54:27) Closing remarks and podcast information

Falling in love can be easy. Staying connected when conflict and stress show up is where the real work begins. On this episode of The Dr. Hyman Show, I sit down with relationship repair expert Baya Voce to explore why healthy relationships aren’t defined by the absence of conflict, but by the ability to repair and reconnect—and why repair depends as much on nervous system regulation as communication. Watch the full conversation on YouTube or listen wherever you get your podcasts. Here’s what we unpack: • Why conflict isn’t the real problem in relationships—and what actually keeps couples connected • What happens in the body during arguments, and why nervous system regulation matters more than the “right” words • How past relationship wounds and attachment patterns shape the way we react during conflict • Practical ways couples can repair after conflict and reconnect more quickly When couples learn how to repair after conflict, even difficult moments can become opportunities for deeper connection and growth. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by PerfectAmino, BON CHARGE, Timeline, BIOptimizers, Maui Nui and Made In Cookware. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Upgrade your routine. Head to boncharge.com/hyman and use code HYMAN for 15% off. Receive 20% off a subscription at timeline.com/drhyman. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman. Head to madeincookware.com and use the code DRHYMAN for 10% off your order. (0:00) Falling in love vs. staying in love (0:31) Healthy conflict and relationship dynamics (1:22) Introduction to Baya Voce and modern relationship evolution (3:15) High expectations and the virtual culture's impact on relationships (8:25) The importance of relationship models and repair mechanisms (10:12) Exploring the stages of a relationship (18:17) Dealing with past relationship baggage (24:08) Training the nervous system for conflict resolution (28:26) Recognizing physiological cues in relationships (31:05) Breathwork and physiological regulation techniques (32:39) Psychedelic therapy's influence on relationships (34:20) Effective listening and differentiation in partnerships (38:10) The power of repair and accepting influence (41:49) Fostering curiosity and perspective in understanding partners (47:20) Setting boundaries for healthy relationships (51:24) Embracing subjective truths within relationships (54:42) Relationships as a means for personal growth (57:06) Navigating the stages of relationships (1:00:22) Exercises for building resilience in partnerships (1:01:51) The role of honesty and weekly practices for relationship health (1:03:25) Communication techniques for relationship maintenance (1:04:00) Reframing relationships through growth and evolution (1:04:56) Psychedelic-assisted couples therapy and MDMA research (1:09:38) Enhancing relationships with meditation and psychedelics (1:11:08) Introduction to The Repair Lab web app